A DNA damage checkpoint response in telomere-initiated senescence FA Fagagna, PM Reaper, L Clay-Farrace, H Fiegler, P Carr, ... Nature 426 (6963), 194-198, 2003 | 3204 | 2003 |
Oxidative stress shortens telomeres T Von Zglinicki Trends in biochemical sciences 27 (7), 339-344, 2002 | 2946 | 2002 |
Cellular senescence: defining a path forward V Gorgoulis, PD Adams, A Alimonti, DC Bennett, O Bischof, C Bishop, ... Cell 179 (4), 813-827, 2019 | 2074 | 2019 |
Fat tissue, aging, and cellular senescence T Tchkonia, DE Morbeck, T Von Zglinicki, J Van Deursen, J Lustgarten, ... Aging cell 9 (5), 667-684, 2010 | 1281 | 2010 |
Mild hyperoxia shortens telomeres and inhibits proliferation of fibroblasts: a model for senescence? T von Zglinicki, G Saretzki, W Döcke, C Lotze Experimental cell research 220 (1), 186-193, 1995 | 1109 | 1995 |
Feedback between p21 and reactive oxygen production is necessary for cell senescence JF Passos, G Nelson, C Wang, T Richter, C Simillion, CJ Proctor, S Miwa, ... Molecular systems biology 6 (1), 347, 2010 | 1027 | 2010 |
Cellular and molecular mechanisms of stress-induced premature senescence (SIPS) of human diploid fibroblasts and melanocytes O Toussaint, EE Medrano, T von Zglinicki Experimental gerontology 35 (8), 927-945, 2000 | 857 | 2000 |
Cellular senescence drives age-dependent hepatic steatosis M Ogrodnik, S Miwa, T Tchkonia, D Tiniakos, CL Wilson, A Lahat, CP Day, ... Nature communications 8 (1), 15691, 2017 | 842 | 2017 |
Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence JF Passos, G Saretzki, S Ahmed, G Nelson, T Richter, H Peters, I Wappler, ... PLoS biology 5 (5), e110, 2007 | 807 | 2007 |
A senescent cell bystander effect: senescence‐induced senescence G Nelson, J Wordsworth, C Wang, D Jurk, C Lawless, C Martin‐Ruiz, ... Aging cell 11 (2), 345-349, 2012 | 803 | 2012 |
Chronic inflammation induces telomere dysfunction and accelerates ageing in mice D Jurk, C Wilson, JF Passos, F Oakley, C Correia-Melo, L Greaves, ... Nature communications 5 (1), 4172, 2014 | 795 | 2014 |
DNA damage response and cellular senescence in tissues of aging mice C Wang, D Jurk, M Maddick, G Nelson, C Martin‐Ruiz, T Von Zglinicki Aging cell 8 (3), 311-323, 2009 | 795 | 2009 |
Accumulation of single-strand breaks is the major cause of telomere shortening in human fibroblasts T von Zglinicki, R Pilger, N Sitte Free Radical Biology and Medicine 28 (1), 64-74, 2000 | 680 | 2000 |
Mitochondria are required for pro‐ageing features of the senescent phenotype C Correia‐Melo, FDM Marques, R Anderson, G Hewitt, R Hewitt, J Cole, ... The EMBO journal 35 (7), 724-742, 2016 | 661 | 2016 |
Postmitotic neurons develop a p21‐dependent senescence‐like phenotype driven by a DNA damage response D Jurk, C Wang, S Miwa, M Maddick, V Korolchuk, A Tsolou, ES Gonos, ... Aging cell 11 (6), 996-1004, 2012 | 569 | 2012 |
Role of oxidative stress in telomere length regulation and replicative senescence T Von Zglinicki Annals of the New York Academy of Sciences 908 (1), 99-110, 2000 | 568 | 2000 |
Telomerase does not counteract telomere shortening but protects mitochondrial function under oxidative stress S Ahmed, JF Passos, MJ Birket, T Beckmann, S Brings, H Peters, ... Journal of cell science 121 (7), 1046-1053, 2008 | 553 | 2008 |
Preferential accumulation of single-stranded regions in telomeres of human fibroblasts S Petersen, G Saretzki, T von Zglinicki Experimental cell research 239 (1), 152-160, 1998 | 537 | 1998 |
Gender and telomere length: systematic review and meta-analysis M Gardner, D Bann, L Wiley, R Cooper, R Hardy, D Nitsch, C Martin-Ruiz, ... Experimental gerontology 51, 15-27, 2014 | 532 | 2014 |
Human cell senescence as a DNA damage response T Von Zglinicki, G Saretzki, J Ladhoff, FA di Fagagna, SP Jackson Mechanisms of ageing and development 126 (1), 111-117, 2005 | 527 | 2005 |