Histone H3 lysine 4 methyltransferase KMT2D E Froimchuk, Y Jang, K Ge Gene 627, 337-342, 2017 | 278 | 2017 |
Somatic mutations increase hepatic clonal fitness and regeneration in chronic liver disease M Zhu, T Lu, Y Jia, X Luo, P Gopal, L Li, M Odewole, V Renteria, ... Cell 177 (3), 608-621. e12, 2019 | 204 | 2019 |
Brd4 binds to active enhancers to control cell identity gene induction in adipogenesis and myogenesis JE Lee, YK Park, S Park, Y Jang, N Waring, A Dey, K Ozato, B Lai, ... Nature communications 8 (1), 2217, 2017 | 197 | 2017 |
MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis B Lai, JE Lee, Y Jang, L Wang, W Peng, K Ge Nucleic acids research 45 (11), 6388-6403, 2017 | 161 | 2017 |
HOXA9 reprograms the enhancer landscape to promote leukemogenesis Y Sun, B Zhou, F Mao, J Xu, H Miao, Z Zou, Y Jang, S Cai, M Witkin, ... Cancer cell 34 (4), 643-658. e5, 2018 | 114 | 2018 |
MLL4 prepares the enhancer landscape for Foxp3 induction via chromatin looping K Placek, G Hu, K Cui, D Zhang, Y Ding, JE Lee, Y Jang, C Wang, ... Nature immunology 18 (9), 1035-1045, 2017 | 78 | 2017 |
Depletion of Nsd2-mediated histone H3K36 methylation impairs adipose tissue development and function L Zhuang, Y Jang, YK Park, JE Lee, S Jain, E Froimchuk, A Broun, C Liu, ... Nature Communications 9 (1), 1796, 2018 | 71 | 2018 |
Phospholipase D1 regulates autophagic flux and clearance of α-synuclein aggregates EJ Bae, HJ Lee, YH Jang, S Michael, E Masliah, DS Min, SJ Lee Cell Death & Differentiation 21 (7), 1132-1141, 2014 | 70 | 2014 |
H3. 3K4M destabilizes enhancer H3K4 methyltransferases MLL3/MLL4 and impairs adipose tissue development Y Jang, A Broun, C Wang, YK Park, L Zhuang, JE Lee, E Froimchuk, C Liu, ... Nucleic Acids Research 47 (2), 607-620, 2019 | 62 | 2019 |
Prognostic significance and function of phosphorylated ribosomal protein S6 in esophageal squamous cell carcinoma SH Kim, YH Jang, GC Chau, S Pyo, SH Um Modern Pathology 26 (3), 327-335, 2013 | 62 | 2013 |
H3K4 methyltransferase activity is required for MLL4 protein stability Y Jang, C Wang, L Zhuang, C Liu, K Ge Journal of molecular biology 429 (13), 2046-2054, 2017 | 61 | 2017 |
Triptolide-induced suppression of phospholipase D expression inhibits proliferation of MDA-MB-231 breast cancer cells DW Kang, JY Lee, D Oh, SY Park, TM Woo, MK Kim, MH Park, YH Jang, ... Experimental & molecular medicine 41 (9), 678-685, 2009 | 56 | 2009 |
N-formyl-methionyl-leucyl-phenylalanine (fMLP) promotes osteoblast differentiation via the N-formyl peptide receptor 1-mediated signaling pathway in human mesenchymal stem … MK Shin, YH Jang, HJ Yoo, DW Kang, MH Park, MK Kim, JH Song, ... Journal of Biological Chemistry 286 (19), 17133-17143, 2011 | 47 | 2011 |
Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF Y Zhang, Y Jang, JE Lee, JW Ahn, L Xu, MR Holden, EM Cornett, ... Nature communications 10 (1), 2314, 2019 | 45 | 2019 |
Phospholipase D-mediated autophagic regulation is a potential target for cancer therapy YH Jang, KY Choi, DS Min Cell Death & Differentiation 21 (4), 533-546, 2014 | 45 | 2014 |
Cleavage of phospholipase D1 by caspase promotes apoptosis via modulation of the p53-dependent cell death pathway YH Jang, S Namkoong, YM Kim, SJ Lee, BJ Park, DS Min Cell Death & Differentiation 15 (11), 1782-1793, 2008 | 29 | 2008 |
Differential regulation of apoptosis by caspase-mediated cleavage of phospholipase D isozymes YH Jang, BH Ahn, S Namkoong, YM Kim, JK Jin, YS Kim Cellular signalling 20 (12), 2198-2207, 2008 | 22 | 2008 |
Nuclear localization of phospholipase D1 mediates the activation of nuclear protein kinase Cα and extracellular signal-regulated kinase signaling pathways YH Jang Journal of Biological Chemistry 286 (6), 4680-4689, 2011 | 20 | 2011 |
MLL3/MLL4 methyltransferase activities control early embryonic development and embryonic stem cell differentiation in a lineage-selective manner G Xie, JE Lee, AD Senft, YK Park, Y Jang, S Chakraborty, JJ Thompson, ... Nature Genetics 55 (4), 693-705, 2023 | 19 | 2023 |
MED1 is a lipogenesis coactivator required for postnatal adipose expansion Y Jang, YK Park, JE Lee, D Wan, N Tran, O Gavrilova, K Ge Genes & Development 35 (9-10), 713-728, 2021 | 18 | 2021 |