Trophoblast-specific expression of Hif-1α results in preeclampsia-like symptoms and fetal growth restriction RE Albers, MR Kaufman, BV Natale, C Keoni, K Kulkarni-Datar, S Min, ... Scientific Reports 9 (1), 2742, 2019 | 96 | 2019 |
Rosiglitazone attenuates NF-κB-mediated Nox4 upregulation in hyperglycemia-activated endothelial cells CR Williams, X Lu, RL Sutliff, CM Hart American Journal of Physiology-Cell Physiology 303 (2), C213-C223, 2012 | 75 | 2012 |
NADPH oxidase-2 mediates zinc deficiency-induced oxidative stress and kidney damage MS Li, SE Adesina, CL Ellis, JL Gooch, RS Hoover, CR Williams American Journal of Physiology-Cell Physiology, 2017 | 70 | 2017 |
Zinc deficiency induces hypertension by promoting renal Na+ reabsorption CR Williams, M Mistry, AM Cheriyan, JM Williams, MK Naraine, CL Ellis, ... American Journal of Physiology-Renal Physiology 316 (4), F646-F653, 2019 | 50 | 2019 |
Calcineurin inhibitors and immunosuppression–a tale of two isoforms CR Williams, JL Gooch Expert reviews in molecular medicine 14, e14, 2012 | 47 | 2012 |
Calcineurin Aβ regulates NADPH oxidase (Nox) expression and activity via nuclear factor of activated T cells (NFAT) in response to high glucose CR Williams, JL Gooch Journal of Biological Chemistry 289 (8), 4896-4905, 2014 | 28 | 2014 |
Calcineurin inhibitors: a double-edged sword AC Ume, TY Wenegieme, CR Williams American Journal of Physiology-Renal Physiology 320 (3), F336-F341, 2021 | 27 | 2021 |
Extracellular zinc and ATP-gated P2X receptor calcium entry channels: New zinc receptors as physiological sensors and therapeutic targets EM Schwiebert, L Liang, NL Cheng, CR Williams, D Olteanu, EA Welty, ... Purinergic Signalling 1, 299-310, 2005 | 27 | 2005 |
Intracellular cholesterol stimulates ENaC by interacting with phosphatidylinositol‑4, 5‑bisphosphate and mediates cyclosporine A-induced hypertension YJ Zhai, MM Wu, VA Linck, L Zou, Q Yue, SP Wei, C Song, S Zhang, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1865 (7 …, 2019 | 18 | 2019 |
Spinal cord injury increases pro-inflammatory cytokine expression in kidney at acute and sub-chronic stages S Parvin, CR Williams, SA Jarrett, SM Garraway Inflammation 44 (6), 2346-2361, 2021 | 17 | 2021 |
Hypoxia inhibits expression and function of mitochondrial thioredoxin 2 to promote pulmonary hypertension SE Adesina, BE Wade, KM Bijli, BY Kang, CR Williams, J Ma, YM Go, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 312 (5 …, 2017 | 16 | 2017 |
Calcineurin inhibitor (CNI)‐associated skin cancers: New insights on exploring mechanisms by which CNIs downregulate DNA repair machinery AC Ume, JM Pugh, MG Kemp, CR Williams Photodermatology, photoimmunology & photomedicine 36 (6), 433-440, 2020 | 15 | 2020 |
Zinc deficiency: A potential hidden driver of the detrimental cycle of chronic kidney disease and hypertension AC Ume, TY Wenegieme, DN Adams, SE Adesina, CR Williams Kidney360 4 (3), 398-404, 2023 | 12 | 2023 |
Compensatory renal hypertrophy following uninephrectomy is calcineurin‐independent CR Williams, BM Wynne, M Walker, RS Hoover, JL Gooch Journal of Cellular and Molecular Medicine 18 (12), 2361-2366, 2014 | 12 | 2014 |
Tacrolimus induces fibroblast-to-myofibroblast transition via a TGF-β-dependent mechanism to contribute to renal fibrosis AC Ume, TY Wenegieme, JN Shelby, CDB Paul-Onyia, AMJ Waite 3rd, ... American Journal of Physiology-Renal Physiology 324 (5), F433-F445, 2023 | 7 | 2023 |
Calcineurin A-α suppression drives nuclear factor-κB-mediated NADPH oxidase-2 upregulation AM Cheriyan, AC Ume, CE Francis, KN King, VA Linck, Y Bai, H Cai, ... American Journal of Physiology-Renal Physiology, 2021 | 7 | 2021 |
Nutritional intervention restores muscle but not kidney phenotypes in adult calcineurin Aα null mice K Madsen, RN Reddy, SR Price, CR Williams, JL Gooch Plos one 8 (4), e62503, 2013 | 5 | 2013 |
Latent transforming growth factor beta binding protein 4: A regulator of mitochondrial function in acute kidney injury K Neikirk, AC Ume, P Prasad, AG Marshall, J Rockwood, TY Wenegieme, ... Aging cell 22 (12), e14019, 2023 | 1 | 2023 |