Transfer of intestinal microbiota from lean donors increases insulin sensitivity in individuals with metabolic syndrome A Vrieze, E Van Nood, F Holleman, J Salojärvi, RS Kootte, ... Gastroenterology 143 (4), 913-916. e7, 2012 | 3031 | 2012 |
Stimulation of lipogenesis by pharmacological activation of the liver X receptor leads to production of large, triglyceride-rich very low density lipoprotein particles A Grefhorst, BM Elzinga, PJ Voshol, T Plo, T Kok, VW Bloks, ... Journal of Biological Chemistry 277 (37), 34182-34190, 2002 | 580 | 2002 |
Beyond intestinal soap—bile acids in metabolic control F Kuipers, VW Bloks, AK Groen Nature Reviews Endocrinology 10 (8), 488-498, 2014 | 443 | 2014 |
24 (S)-hydroxycholesterol participates in a liver X receptor-controlled pathway in astrocytes that regulates apolipoprotein E-mediated cholesterol efflux K Abildayeva, PJ Jansen, V Hirsch-Reinshagen, VW Bloks, AHF Bakker, ... Journal of Biological Chemistry 281 (18), 12799-12808, 2006 | 264 | 2006 |
Increased hepatobiliary and fecal cholesterol excretion upon activation of the liver X receptor is independent of ABCA1 T Plo, T Kok, VW Bloks, MJ Smit, R Havinga, G Chimini, AK Groen, ... Journal of Biological Chemistry 277 (37), 33870-33877, 2002 | 259 | 2002 |
Regulation of bile acid synthesis by the nuclear receptor Rev-erbα H Duez, JN Van Der Veen, C Duhem, B Pourcet, T Touvier, C Fontaine, ... Gastroenterology 135 (2), 689-698. e5, 2008 | 227 | 2008 |
In utero undernutrition in male mice programs liver lipid metabolism in the second-generation offspring involving altered Lxra DNA methylation D Martínez, T Pentinat, S Ribó, C Daviaud, VW Bloks, J Cebria, ... Cell metabolism 19 (6), 941-951, 2014 | 206 | 2014 |
Hepatobiliary cholesterol transport is not impaired in Abca1-null mice lacking HDL AK Groen, VW Bloks, RHJ Bandsma, R Ottenhoff, G Chimini, F Kuipers The Journal of clinical investigation 108 (6), 843-850, 2001 | 206 | 2001 |
Improved glycemic control with colesevelam treatment in patients with type 2 diabetes is not directly associated with changes in bile acid metabolism G Brufau, F Stellaard, K Prado, VW Bloks, E Jonkers, R Boverhof, ... Hepatology 52 (4), 1455-1464, 2010 | 204 | 2010 |
Impaired secretion of very low density lipoprotein-triglycerides by apolipoprotein E-deficient mouse hepatocytes. F Kuipers, MC Jong, Y Lin, M Eck, R Havinga, V Bloks, HJ Verkade, ... The Journal of clinical investigation 100 (11), 2915-2922, 1997 | 202 | 1997 |
Peroxisome proliferator-activated receptor alpha (PPARalpha)-mediated regulation of multidrug resistance 2 (Mdr2) expression and function in mice T Kok, VW Bloks, H Wolters, R Havinga, PLM Jansen, B Staels, F Kuipers Biochemical Journal 369 (3), 539-547, 2003 | 179 | 2003 |
Sitosterolemia in ABC-transporter G5-deficient mice is aggravated on activation of the liver-X receptor T Plösch, VW Bloks, Y Terasawa, S Berdy, K Siegler, F Van Der Sluijs, ... Gastroenterology 126 (1), 290-300, 2004 | 171 | 2004 |
The liver X-receptor gene promoter is hypermethylated in a mouse model of prenatal protein restriction EME van Straten, VW Bloks, NCA Huijkman, JFW Baller, H Meer, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2010 | 167 | 2010 |
Apolipoprotein E participates in the regulation of very low density lipoprotein-triglyceride secretion by the liver AR Mensenkamp, MC Jong, H van Goor, MJA van Luyn, V Bloks, ... Journal of biological chemistry 274 (50), 35711-35718, 1999 | 158 | 1999 |
Malnutrition-associated liver steatosis and ATP depletion is caused by peroxisomal and mitochondrial dysfunction T van Zutphen, J Ciapaite, VW Bloks, C Ackereley, A Gerding, ... Journal of hepatology 65 (6), 1198-1208, 2016 | 146 | 2016 |
Liver X receptor activation restores memory in aged AD mice without reducing amyloid T Vanmierlo, K Rutten, J Dederen, VW Bloks, F Kuipers, A Kiliaan, ... Neurobiology of aging 32 (7), 1262-1272, 2011 | 144 | 2011 |
Intestinal farnesoid X receptor controls transintestinal cholesterol excretion in mice JF de Boer, M Schonewille, M Boesjes, H Wolters, VW Bloks, T Bos, ... Gastroenterology 152 (5), 1126-1138. e6, 2017 | 131 | 2017 |
Transintestinal cholesterol transport is active in mice and humans and controls ezetimibe-induced fecal neutral sterol excretion L Jakulj, TH van Dijk, JF de Boer, RS Kootte, M Schonewille, Y Paalvast, ... Cell metabolism 24 (6), 783-794, 2016 | 127 | 2016 |
Statins increase hepatic cholesterol synthesis and stimulate fecal cholesterol elimination in mice M Schonewille, JF de Boer, L Mele, H Wolters, VW Bloks, JC Wolters, ... Journal of lipid research 57 (8), 1455-1464, 2016 | 119 | 2016 |
Reduction of cholesterol absorption by dietary plant sterols and stanols in mice is independent of the Abcg5/8 transporter T Plösch, JK Kruit, VW Bloks, NCA Huijkman, R Havinga, GS Duchateau, ... The Journal of nutrition 136 (8), 2135-2140, 2006 | 119 | 2006 |