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TR Hirst
TR Hirst
GPN Vaccines
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引用次数
引用次数
年份
Protein disulphide isomerase: building bridges in protein folding
RB Freedman, TR Hirst, MF Tuite
Trends in biochemical sciences 19 (8), 331-336, 1994
9451994
Membrane traffic and the cellular uptake of cholera toxin
WI Lencer, TR Hirst, RK Holmes
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1450 (3), 177-190, 1999
3301999
Targeting of cholera toxin and Escherichia coli heat labile toxin in polarized epithelia: role of COOH-terminal KDEL.
WI Lencer, C Constable, S Moe, MG Jobling, HM Webb, S Ruston, ...
The Journal of cell biology 131 (4), 951-962, 1995
2941995
Cholera toxin: a paradigm for multi-functional engagement of cellular mechanisms
L Haan, TR Hirst
Molecular membrane biology 21 (2), 77-92, 2004
2752004
Immune modulation by the cholera-like enterotoxins: from adjuvant to therapeutic
NA Williams, TR Hirst, TO Nashar
Immunology today 20 (2), 95-101, 1999
2751999
Conformation of protein secreted across bacterial outer membranes: a study of enterotoxin translocation from Vibrio cholerae.
TR Hirst, J Holmgren
Proceedings of the National Academy of Sciences 84 (21), 7418-7422, 1987
2191987
Biofilm formation by Helicobacter pylori
RM Stark, GJ Gerwig, RS Pitman, LF Potts, NA Williams, J Greenman, ...
Letters in applied microbiology 28 (2), 121-126, 1999
2111999
Mechanism of toxin secretion by Vibrio cholerae investigated in strains harboring plasmids that encode heat-labile enterotoxins of Escherichia coli.
TR Hirst, J Sanchez, JB Kaper, SJ Hardy, J Holmgren
Proceedings of the National Academy of Sciences 81 (24), 7752-7756, 1984
1941984
Potent immunogenicity of the B subunits of Escherichia coli heat-labile enterotoxin: receptor binding is essential and induces differential modulation of lymphocyte subsets.
TO Nashar, HM Webb, S Eaglestone, NA Williams, TR Hirst
Proceedings of the National Academy of Sciences 93 (1), 226-230, 1996
1901996
Coordinated assembly of multisubunit proteins: oligomerization of bacterial enterotoxins in vivo and in vitro.
SJ Hardy, J Holmgren, S Johansson, J Sanchez, TR Hirst
Proceedings of the National Academy of Sciences 85 (19), 7109-7113, 1988
1891988
Energy is Required for Maturation of Exported Proteins in Escherichia coli
HG Enequist, TR Hirst, S Harayama, SJS Hardy, LL Randall
European Journal of Biochemistry 116 (2), 227-233, 1981
1851981
A homologue of the Escherichia coli DsbA protein involved in disulphide bond formation is required for enterotoxin biogenesis in Vibrio cholerae
J Yu, H Webb, TR Hirst
Molecular microbiology 6 (14), 1949-1958, 1992
1831992
Investigations into the mechanism of action of the antibacterial agent norfloxacin
GC Crumplin, M Kenwright, T Hirst
Journal of Antimicrobial Chemotherapy 13 (suppl_B), 9-23, 1984
1791984
A mutant cholera toxin B subunit that binds GM1-ganglioside but lacks immunomodulatory or toxic activity
AT Aman, S Fraser, EA Merritt, C Rodigherio, M Kenny, M Ahn, WGJ Hol, ...
Proceedings of the National Academy of Sciences 98 (15), 8536-8541, 2001
1462001
Escherichia coli Heat-Labile Enterotoxin B Subunit Is a More Potent Mucosal Adjuvant than Its Closely Related Homologue, the B Subunit of Cholera Toxin
DG Millar, TR Hirst, DP Snider
Infection and immunity 69 (5), 3476-3482, 2001
1432001
Synthesis of a precursor to the B subunit of heat-labile enterotoxin in Escherichia coli
ET Palva, TR Hirst, SJ Hardy, J Holmgren, L Randall
Journal of Bacteriology 146 (1), 325-330, 1981
1231981
F‐actin dynamics control segregation of the TCR signaling cascade to clustered lipid rafts
S Valensin, SR Paccani, C Ulivieri, D Mercati, S Pacini, L Patrussi, T Hirst, ...
European journal of immunology 32 (2), 435-446, 2002
1222002
Transient entry of enterotoxin subunits into the periplasm occurs during their secretion from Vibrio cholerae
TR Hirst, J Holmgren
Journal of bacteriology 169 (3), 1037-1045, 1987
1221987
Structural studies of receptor binding by cholera toxin mutants
EA Merritt, S Sarfaty, WIMGJ Hol, MG Jobling, RK Holmes, T Chang, ...
Protein science 6 (7), 1516-1528, 1997
1181997
Cellular location of heat-labile enterotoxin in Escherichia coli
TR Hirst, LL Randall, SJ Hardy
Journal of bacteriology 157 (2), 637-642, 1984
1141984
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