Protein disulphide isomerase: building bridges in protein folding RB Freedman, TR Hirst, MF Tuite Trends in biochemical sciences 19 (8), 331-336, 1994 | 945 | 1994 |
Membrane traffic and the cellular uptake of cholera toxin WI Lencer, TR Hirst, RK Holmes Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1450 (3), 177-190, 1999 | 330 | 1999 |
Targeting of cholera toxin and Escherichia coli heat labile toxin in polarized epithelia: role of COOH-terminal KDEL. WI Lencer, C Constable, S Moe, MG Jobling, HM Webb, S Ruston, ... The Journal of cell biology 131 (4), 951-962, 1995 | 294 | 1995 |
Cholera toxin: a paradigm for multi-functional engagement of cellular mechanisms L Haan, TR Hirst Molecular membrane biology 21 (2), 77-92, 2004 | 275 | 2004 |
Immune modulation by the cholera-like enterotoxins: from adjuvant to therapeutic NA Williams, TR Hirst, TO Nashar Immunology today 20 (2), 95-101, 1999 | 275 | 1999 |
Conformation of protein secreted across bacterial outer membranes: a study of enterotoxin translocation from Vibrio cholerae. TR Hirst, J Holmgren Proceedings of the National Academy of Sciences 84 (21), 7418-7422, 1987 | 219 | 1987 |
Biofilm formation by Helicobacter pylori RM Stark, GJ Gerwig, RS Pitman, LF Potts, NA Williams, J Greenman, ... Letters in applied microbiology 28 (2), 121-126, 1999 | 211 | 1999 |
Mechanism of toxin secretion by Vibrio cholerae investigated in strains harboring plasmids that encode heat-labile enterotoxins of Escherichia coli. TR Hirst, J Sanchez, JB Kaper, SJ Hardy, J Holmgren Proceedings of the National Academy of Sciences 81 (24), 7752-7756, 1984 | 194 | 1984 |
Potent immunogenicity of the B subunits of Escherichia coli heat-labile enterotoxin: receptor binding is essential and induces differential modulation of lymphocyte subsets. TO Nashar, HM Webb, S Eaglestone, NA Williams, TR Hirst Proceedings of the National Academy of Sciences 93 (1), 226-230, 1996 | 190 | 1996 |
Coordinated assembly of multisubunit proteins: oligomerization of bacterial enterotoxins in vivo and in vitro. SJ Hardy, J Holmgren, S Johansson, J Sanchez, TR Hirst Proceedings of the National Academy of Sciences 85 (19), 7109-7113, 1988 | 189 | 1988 |
Energy is Required for Maturation of Exported Proteins in Escherichia coli HG Enequist, TR Hirst, S Harayama, SJS Hardy, LL Randall European Journal of Biochemistry 116 (2), 227-233, 1981 | 185 | 1981 |
A homologue of the Escherichia coli DsbA protein involved in disulphide bond formation is required for enterotoxin biogenesis in Vibrio cholerae J Yu, H Webb, TR Hirst Molecular microbiology 6 (14), 1949-1958, 1992 | 183 | 1992 |
Investigations into the mechanism of action of the antibacterial agent norfloxacin GC Crumplin, M Kenwright, T Hirst Journal of Antimicrobial Chemotherapy 13 (suppl_B), 9-23, 1984 | 179 | 1984 |
A mutant cholera toxin B subunit that binds GM1-ganglioside but lacks immunomodulatory or toxic activity AT Aman, S Fraser, EA Merritt, C Rodigherio, M Kenny, M Ahn, WGJ Hol, ... Proceedings of the National Academy of Sciences 98 (15), 8536-8541, 2001 | 146 | 2001 |
Escherichia coli Heat-Labile Enterotoxin B Subunit Is a More Potent Mucosal Adjuvant than Its Closely Related Homologue, the B Subunit of Cholera Toxin DG Millar, TR Hirst, DP Snider Infection and immunity 69 (5), 3476-3482, 2001 | 143 | 2001 |
Synthesis of a precursor to the B subunit of heat-labile enterotoxin in Escherichia coli ET Palva, TR Hirst, SJ Hardy, J Holmgren, L Randall Journal of Bacteriology 146 (1), 325-330, 1981 | 123 | 1981 |
F‐actin dynamics control segregation of the TCR signaling cascade to clustered lipid rafts S Valensin, SR Paccani, C Ulivieri, D Mercati, S Pacini, L Patrussi, T Hirst, ... European journal of immunology 32 (2), 435-446, 2002 | 122 | 2002 |
Transient entry of enterotoxin subunits into the periplasm occurs during their secretion from Vibrio cholerae TR Hirst, J Holmgren Journal of bacteriology 169 (3), 1037-1045, 1987 | 122 | 1987 |
Structural studies of receptor binding by cholera toxin mutants EA Merritt, S Sarfaty, WIMGJ Hol, MG Jobling, RK Holmes, T Chang, ... Protein science 6 (7), 1516-1528, 1997 | 118 | 1997 |
Cellular location of heat-labile enterotoxin in Escherichia coli TR Hirst, LL Randall, SJ Hardy Journal of bacteriology 157 (2), 637-642, 1984 | 114 | 1984 |