Method Gene ontology analysis for RNA-seq: accounting for selection bias MD Young, MJ Wakefield, GK Smyth, A Oshlack | 6184* | 2010 |
From RNA-seq reads to differential expression results A Oshlack, MD Robinson, MD Young Genome biology 11 (12), 220, 2010 | 959 | 2010 |
SoupX removes ambient RNA contamination from droplet-based single-cell RNA sequencing data MD Young, S Behjati Gigascience 9 (12), giaa151, 2020 | 739 | 2020 |
Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumors MD Young, TJ Mitchell, FAV Braga, MGB Tran, BJ Stewart, JR Ferdinand, ... Science 361 (6402), 594-599, 2018 | 596 | 2018 |
BBKNN: fast batch alignment of single cell transcriptomes K Polański, MD Young, Z Miao, KB Meyer, SA Teichmann, JE Park Bioinformatics 36 (3), 964-965, 2020 | 589 | 2020 |
Intra-tumour diversification in colorectal cancer at the single-cell level SF Roerink, N Sasaki, H Lee-Six, MD Young, LB Alexandrov, S Behjati, ... Nature 556 (7702), 457-462, 2018 | 485 | 2018 |
Decoding human fetal liver haematopoiesis DM Popescu, RA Botting, E Stephenson, K Green, S Webb, L Jardine, ... Nature 574 (7778), 365-371, 2019 | 465 | 2019 |
ChIP-seq analysis reveals distinct H3K27me3 profiles that correlate with transcriptional activity MD Young, TA Willson, MJ Wakefield, E Trounson, DJ Hilton, ME Blewitt, ... Nucleic Acids Research 39 (17), 7415-7427, 2011 | 342 | 2011 |
Spatiotemporal immune zonation of the human kidney BJ Stewart, JR Ferdinand, MD Young, TJ Mitchell, KW Loudon, AM Riding, ... Science 365 (6460), 1461-1466, 2019 | 328 | 2019 |
Recurrent mutation of IGF signalling genes and distinct patterns of genomic rearrangement in osteosarcoma S Behjati, PS Tarpey, K Haase, H Ye, MD Young, LB Alexandrov, ... Nature communications 8 (1), 15936, 2017 | 221 | 2017 |
goseq: Gene Ontology testing for RNA-seq datasets MD Young, MJ Wakefield, GK Smyth, A Oshlack | 192 | 2011 |
Inherent mosaicism and extensive mutation of human placentas THH Coorens, TRW Oliver, R Sanghvi, U Sovio, E Cook, R Vento-Tormo, ... Nature 592 (7852), 80-85, 2021 | 161 | 2021 |
Rearrangement bursts generate canonical gene fusions in bone and soft tissue tumors ND Anderson, R de Borja, MD Young, F Fuligni, A Rosic, ND Roberts, ... Science 361 (6405), eaam8419, 2018 | 153 | 2018 |
Global changes in the mammary epigenome are induced by hormonal cues and coordinated by Ezh2 B Pal, T Bouras, W Shi, F Vaillant, JM Sheridan, N Fu, K Breslin, K Jiang, ... Cell reports 3 (2), 411-426, 2013 | 152 | 2013 |
The driver landscape of sporadic chordoma PS Tarpey, S Behjati, MD Young, I Martincorena, LB Alexandrov, ... Nature communications 8 (1), 890, 2017 | 140 | 2017 |
Single-cell sequencing reveals clonal expansions of pro-inflammatory synovial CD8 T cells expressing tissue-homing receptors in psoriatic arthritis F Penkava, MDC Velasco-Herrera, MD Young, N Yager, LN Nwosu, ... Nature communications 11 (1), 1-11, 2020 | 129 | 2020 |
Embryonal precursors of Wilms tumor THH Coorens, TD Treger, R Al-Saadi, L Moore, MGB Tran, TJ Mitchell, ... Science 366 (6470), 1247-1251, 2019 | 128 | 2019 |
Recurrent rearrangements of FOS and FOSB define osteoblastoma MW Fittall, W Mifsud, N Pillay, H Ye, AC Strobl, A Verfaillie, ... Nature communications 9 (1), 2150, 2018 | 122 | 2018 |
Tumor to normal single-cell mRNA comparisons reveal a pan-neuroblastoma cancer cell G Kildisiute, WM Kholosy, MD Young, K Roberts, R Elmentaite, ... Science Advances 7 (6), eabd3311, 2021 | 105 | 2021 |
Single-cell atlas of the first intra-mammalian developmental stage of the human parasite Schistosoma mansoni CLD Soria, J Lee, T Chong, A Coghlan, A Tracey, MD Young, T Andrews, ... Nature Communications 11 (1), 1-16, 2020 | 67 | 2020 |