Rare Variants in APP, PSEN1 and PSEN2 Increase Risk for AD in Late-Onset Alzheimer's Disease Families C Cruchaga, S Chakraverty, K Mayo, FLM Vallania, RD Mitra, K Faber, ... PloS one 7 (2), e31039, 2012 | 391 | 2012 |
Single-cell chromatin modification profiling reveals increased epigenetic variations with aging P Cheung, F Vallania, HC Warsinske, M Donato, S Schaffert, SE Chang, ... Cell, 2018 | 327 | 2018 |
A multi-cohort study of the immune factors associated with M. tuberculosis infection outcomes R Roy Chowdhury, F Vallania, Q Yang, CJ Lopez Angel, F Darboe, ... Nature 560 (7720), 644-648, 2018 | 255 | 2018 |
Quantification of rare allelic variants from pooled genomic DNA TE Druley, FLM Vallania, DJ Wegner, KE Varley, OL Knowles, JA Bonds, ... Nature methods 6 (4), 263-265, 2009 | 224 | 2009 |
Increased monocyte count as a cellular biomarker for poor outcomes in fibrotic diseases: a retrospective, multicentre cohort study MKD Scott, K Quinn, Q Li, R Carroll, H Warsinske, F Vallania, S Chen, ... The Lancet Respiratory Medicine 7 (6), 497-508, 2019 | 214 | 2019 |
Cell-centred meta-analysis reveals baseline predictors of anti-TNFα non-response in biopsy and blood of patients with IBD R Gaujoux, E Starosvetsky, N Maimon, F Vallania, H Bar-Yoseph, ... Gut 68 (4), 604-614, 2019 | 183 | 2019 |
Interpretation of biological experiments changes with evolution of the Gene Ontology and its annotations A Tomczak, JM Mortensen, R Winnenburg, C Liu, DT Alessi, V Swamy, ... Scientific reports 8 (1), 5115, 2018 | 163 | 2018 |
Performance of common analysis methods for detecting low-frequency single nucleotide variants in targeted next-generation sequence data DH Spencer, M Tyagi, F Vallania, AJ Bredemeyer, JD Pfeifer, RD Mitra, ... The Journal of Molecular Diagnostics 16 (1), 75-88, 2014 | 160 | 2014 |
Leveraging heterogeneity across multiple datasets increases cell-mixture deconvolution accuracy and reduces biological and technical biases F Vallania, A Tam, S Lofgren, S Schaffert, TD Azad, E Bongen, W Haynes, ... Nature communications 9 (1), 4735, 2018 | 148 | 2018 |
Methods to increase reproducibility in differential gene expression via meta-analysis TE Sweeney, WA Haynes, F Vallania, JP Ioannidis, P Khatri Nucleic acids research 45 (1), e1-e1, 2017 | 146 | 2017 |
Empowering multi-cohort gene expression analysis to increase reproducibility WA Haynes, F Vallania, C Liu, E Bongen, A Tomczak, M Andres-Terrè, ... Pacific symposium on biocomputing 2017, 144-153, 2017 | 135 | 2017 |
Multicohort analysis reveals baseline transcriptional predictors of influenza vaccination responses H team Science Immunology, 2017 | 126 | 2017 |
TATA is a modular component of synthetic promoters I Mogno, F Vallania, RD Mitra, BA Cohen Genome research 20 (10), 1391-1397, 2010 | 120 | 2010 |
Cardiac signaling genes exhibit unexpected sequence diversity in sporadic cardiomyopathy, revealing HSPB7 polymorphisms associated with disease SJ Matkovich, DJ Van Booven, A Hindes, MY Kang, TE Druley, ... The Journal of clinical investigation 120 (1), 280-289, 2010 | 94 | 2010 |
Cellular senescence impairs the reversibility of pulmonary arterial hypertension DE Van Der Feen, GPL Bossers, QAJ Hagdorn, JR Moonen, K Kurakula, ... Science Translational Medicine 12 (554), eaaw4974, 2020 | 91 | 2020 |
Genome-wide discovery of functional transcription factor binding sites by comparative genomics: the case of Stat3 F Vallania, D Schiavone, S Dewilde, E Pupo, S Garbay, R Calogero, ... Proceedings of the National Academy of Sciences 106 (13), 5117-5122, 2009 | 89 | 2009 |
High-throughput discovery of rare insertions and deletions in large cohorts FLM Vallania, TE Druley, E Ramos, J Wang, I Borecki, M Province, ... Genome research 20 (12), 1711-1718, 2010 | 81 | 2010 |
Rare missense variants in CHRNB4 are associated with reduced risk of nicotine dependence G Haller, T Druley, FL Vallania, RD Mitra, P Li, G Akk, JH Steinbach, ... Human molecular genetics 21 (3), 647-655, 2012 | 77 | 2012 |
The RhoU/Wrch1 Rho GTPase gene is a common transcriptional target of both the gp130/STAT3 and Wnt-1 pathways D Schiavone, S Dewilde, F Vallania, J Turkson, F Di Cunto, V Poli Biochemical Journal 421 (2), 283-292, 2009 | 72 | 2009 |
A 20-gene set predictive of progression to severe dengue M Robinson, TE Sweeney, R Barouch-Bentov, MK Sahoo, L Kalesinskas, ... Cell reports 26 (5), 1104-1111. e4, 2019 | 71 | 2019 |