The Dnmt3a PWWP domain reads histone 3 lysine 36 trimethylation and guides DNA methylation A Dhayalan, A Rajavelu, P Rathert, R Tamas, RZ Jurkowska, S Ragozin, ... Journal of Biological Chemistry 285 (34), 26114-26120, 2010 | 623 | 2010 |
Transcriptional plasticity promotes primary and acquired resistance to BET inhibition P Rathert, M Roth, T Neumann, F Muerdter, JS Roe, M Muhar, S Deswal, ... Nature 525 (7570), 543-547, 2015 | 500 | 2015 |
Chromatin methylation activity of Dnmt3a and Dnmt3a/3L is guided by interaction of the ADD domain with the histone H3 tail Y Zhang, R Jurkowska, S Soeroes, A Rajavelu, A Dhayalan, I Bock, ... Nucleic acids research 38 (13), 4246-4253, 2010 | 456 | 2010 |
Protein lysine methyltransferase G9a acts on non-histone targets P Rathert, A Dhayalan, M Murakami, X Zhang, R Tamas, R Jurkowska, ... Nature chemical biology 4 (6), 344-346, 2008 | 404 | 2008 |
The histone chaperone CAF-1 safeguards somatic cell identity S Cheloufi, U Elling, B Hopfgartner, YL Jung, J Murn, M Ninova, ... Nature 528 (7581), 218-224, 2015 | 287 | 2015 |
Specificity analysis-based identification of new methylation targets of the SET7/9 protein lysine methyltransferase A Dhayalan, S Kudithipudi, P Rathert, A Jeltsch Chemistry & Biology 18 (1), 111-120, 2011 | 191 | 2011 |
Detailed specificity analysis of antibodies binding to modified histone tails with peptide arrays I Bock, A Dhayalan, S Kudithipudi, O Brandt, P Rathert, A Jeltsch Epigenetics 6 (2), 256-263, 2011 | 117 | 2011 |
Analysis of the substrate specificity of the Dim-5 histone lysine methyltransferase using peptide arrays P Rathert, X Zhang, C Freund, X Cheng, A Jeltsch Chemistry & biology 15 (1), 5-11, 2008 | 97 | 2008 |
Modular fluorescence complementation sensors for live cell detection of epigenetic signals at endogenous genomic sites C Lungu, S Pinter, J Broche, P Rathert, A Jeltsch Nature communications 8 (1), 1-13, 2017 | 75 | 2017 |
MTHFD1 interaction with BRD4 links folate metabolism to transcriptional regulation S Sdelci, AF Rendeiro, P Rathert, W You, JMG Lin, A Ringler, G Hofstätter, ... Nature genetics 51 (6), 990-998, 2019 | 74 | 2019 |
Mutations of R882 change flanking sequence preferences of the DNA methyltransferase DNMT3A and cellular methylation patterns M Emperle, S Adam, S Kunert, M Dukatz, A Baude, C Plass, P Rathert, ... Nucleic acids research 47 (21), 11355-11367, 2019 | 63 | 2019 |
Substrate specificity analysis and novel substrates of the protein lysine methyltransferase NSD1 S Kudithipudi, C Lungu, P Rathert, N Happel, A Jeltsch Chemistry & biology 21 (2), 226-237, 2014 | 63 | 2014 |
Phosphorylation of serine-515 activates the Mammalian maintenance methyltransferase Dnmt1 R Goyal, P Rathert, H Laser, H Gowher, A Jeltsch Epigenetics 2 (3), 155-160, 2007 | 56 | 2007 |
Specificity of protein lysine methyltransferases and methods for detection of lysine methylation of non-histone proteins P Rathert, A Dhayalan, H Ma, A Jeltsch Molecular BioSystems 4 (12), 1186-1190, 2008 | 53 | 2008 |
Mapping the chemical chromatin reactivation landscape identifies BRD4-TAF1 cross-talk S Sdelci, CH Lardeau, C Tallant, F Klepsch, B Klaiber, J Bennett, ... Nature chemical biology 12 (7), 504-510, 2016 | 48 | 2016 |
Application of DNA methyltransferases in targeted DNA methylation A Jeltsch, RZ Jurkowska, TP Jurkowski, K Liebert, P Rathert, ... Applied microbiology and biotechnology 75 (6), 1233-1240, 2007 | 45 | 2007 |
Reversible inactivation of the CG specific SssI DNA (cytosine‐C5)‐methyltransferase with a photocleavable protecting group P Rathert, T Raskó, M Roth, K Ślaska‐Kiss, A Pingoud, A Kiss, A Jeltsch Chembiochem 8 (2), 202-207, 2007 | 45 | 2007 |
Continuous enzymatic assay for histone lysine methyltransferases P Rathert, X Cheng, A Jeltsch Biotechniques 43 (5), 602-608, 2007 | 42 | 2007 |
Chromatin-dependent allosteric regulation of DNMT3A activity by MeCP2 A Rajavelu, C Lungu, M Emperle, M Dukatz, A Bröhm, J Broche, I Hanelt, ... Nucleic acids research 46 (17), 9044-9056, 2018 | 38 | 2018 |
A continuous protein methyltransferase (G9a) assay for enzyme activity measurement and inhibitor screening A Dhayalan, E Dimitrova, P Rathert, A Jeltsch Journal of biomolecular screening 14 (9), 1129-1133, 2009 | 38 | 2009 |