Methods for improving aptamer binding affinity H Hasegawa, N Savory, K Abe, K Ikebukuro Molecules 21 (4), 421, 2016 | 239 | 2016 |
Selection of DNA aptamer against prostate specific antigen using a genetic algorithm and application to sensing N Savory, K Abe, K Sode, K Ikebukuro Biosensors and Bioelectronics 26 (4), 1386-1391, 2010 | 197 | 2010 |
Antibody to CD137 Activated by Extracellular Adenosine Triphosphate Is Tumor Selective and Broadly Effective In Vivo without Systemic Immune Activation M Kamata-Sakurai, Y Narita, Y Hori, T Nemoto, R Uchikawa, M Honda, ... Cancer discovery 11 (1), 158-175, 2021 | 66 | 2021 |
In silico maturation of binding‐specificity of DNA aptamers against Proteus mirabilis N Savory, D Lednor, K Tsukakoshi, K Abe, W Yoshida, S Ferri, BV Jones, ... Biotechnology and bioengineering 110 (10), 2573-2580, 2013 | 51 | 2013 |
Selection of DNA aptamers against uropathogenic Escherichia coli NSM59 by quantitative PCR controlled Cell-SELEX N Savory, J Nzakizwanayo, K Abe, W Yoshida, S Ferri, C Dedi, BV Jones, ... Journal of Microbiological Methods, 2014 | 45 | 2014 |
Simultaneous improvement of specificity and affinity of aptamers against Streptococcus mutans by in silico maturation for biosensor development N Savory, Y Takahashi, K Tsukakoshi, H Hasegawa, M Takase, K Abe, ... Biotechnology and bioengineering 111 (3), 454-461, 2014 | 30 | 2014 |
Improvement of the VEGF binding ability of DNA aptamers through in silico maturation and multimerization strategy T Fukaya, K Abe, N Savory, K Tsukakoshi, W Yoshida, S Ferri, K Sode, ... Journal of Biotechnology 212, 99-105, 2015 | 24 | 2015 |
Development of a novel biosensing system based on the structural change of a polymerized guanine-quadruplex DNA nanostructure Y Morita, W Yoshida, N Savory, SW Han, M Tera, K Nagasawa, ... Biosensors and Bioelectronics 26 (12), 4837-4841, 2011 | 17 | 2011 |
DNA aptamers against the Cry j 2 allergen of Japanese cedar pollen for biosensing applications K Ogihara, N Savory, K Abe, W Yoshida, M Asahi, S Kamohara, ... Biosensors and Bioelectronics 63, 159-165, 2015 | 12 | 2015 |
Two-Dimensional Electrophoresis-Based Selection of Aptamers against an Unidentified Protein in a Tissue Sample N Savory, S Goto, Y Wataru, Y Unuma, M Nakamura, K Abe, S Ferri, ... Analytical Letters, 2013 | 12 | 2013 |
G-quadruplex-forming aptamer enhances the peroxidase activity of myoglobin against luminol K Tsukakoshi, Y Yamagishi, M Kanazashi, K Nakama, D Oshikawa, ... Nucleic Acids Research 49 (11), 6069-6081, 2021 | 11 | 2021 |
Development of HGF‐binding aptamers with the combination of G4 promoter‐derived aptamer selection and in silico maturation T Yokoyama, K Tsukakoshi, W Yoshida, T Saito, K Teramoto, N Savory, ... Biotechnology and Bioengineering 114 (10), 2196-2203, 2017 | 6 | 2017 |
In silico Maturation: Processing Sequences to Improve Biopolymer Function Based On Genetic Algorithms N Savory, K Abe, W Yoshida, K Ikebukuro Applications of Metaheuristics in Process Engineering (http://www.springer …, 2014 | 6 | 2014 |
Development of an automated direct blotting electrophoresis system for bioanalytical applications S Goto, N Savory, K Abe, H Kinoshita, K Ikebukuro Analytical Methods 7 (12), 4881-4884, 2015 | 3 | 2015 |
Anti-cd137 antigen-binding molecule and utilization thereof T Igawa, M Sakurai, S Shimizu, Y Hori, N Hironiwa, N Savory, Y Narita, ... US Patent App. 17/266,024, 2021 | 2 | 2021 |
Method for activating immune response of target cell and composition therefor T Sakashita, N Savory, K Kato, Y Narushima, R Murakami, T Igawa US Patent App. 17/253,714, 2021 | 1 | 2021 |
History of aptamer development N Savory, K Abe, T Saito, K Ikebukuro Aptamers, 1-26, 2017 | 1 | 2017 |
Aptamers as therapeutic tools in neurological diseases L Aaldering, S Krishnan, S Fletcher, SD Wilton, RN Veedu Aptamers, Tools for Nanotherapy and Molecular Imaging, 2016 | 1 | 2016 |
ANTIGEN-BINDING MOLECULE AND COMBINATION T Igawa, N Hironiwa, S Kamikawaji, T Kibayashi, N Savory, F Mimoto US Patent App. 18/394,091, 2024 | | 2024 |
Antigen-binding molecules with improved cytosol-penetrating activity Y Ikawa, N Savory US Patent App. 18/269,099, 2024 | | 2024 |