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Nicolai Siegel
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Four histone variants mark the boundaries of polycistronic transcription units in Trypanosoma brucei
TN Siegel, DR Hekstra, LE Kemp, LM Figueiredo, JE Lowell, D Fenyo, ...
Genes & development 23 (9), 1063-1076, 2009
4222009
Genome-wide analysis of mRNA abundance in two life-cycle stages of Trypanosoma brucei and identification of splicing and polyadenylation sites
TN Siegel, DR Hekstra, X Wang, S Dewell, GAM Cross
Nucleic acids research 38 (15), 4946-4957, 2010
3582010
Evidence for a shared nuclear pore complex architecture that is conserved from the last common eukaryotic ancestor
JA DeGrasse, KN DuBois, D Devos, TN Siegel, A Sali, MC Field, MP Rout, ...
Molecular & Cellular Proteomics 8 (9), 2119-2130, 2009
2302009
Genome organization and DNA accessibility control antigenic variation in trypanosomes
LSM Müller, RO Cosentino, KU Förstner, J Guizetti, C Wedel, N Kaplan, ...
Nature 563 (7729), 121-125, 2018
1762018
Comparative ribosome profiling reveals extensive translational complexity in different Trypanosoma brucei life cycle stages
JJ Vasquez, CC Hon, JT Vanselow, A Schlosser, TN Siegel
Nucleic acids research 42 (6), 3623-3637, 2014
1732014
Strand-specific RNA-Seq reveals widespread and developmentally regulated transcription of natural antisense transcripts in Plasmodium falciparum
TN Siegel, CC Hon, Q Zhang, JJ Lopez-Rubio, C Scheidig-Benatar, ...
BMC genomics 15, 1-16, 2014
1092014
Gene expression in Trypanosoma brucei: lessons from high-throughput RNA sequencing
TN Siegel, K Gunasekera, GAM Cross, T Ochsenreiter
Trends in parasitology 27 (10), 434-441, 2011
1072011
Systematic Study of Sequence Motifs for RNA trans Splicing in Trypanosoma brucei
TN Siegel, KSW Tan, GAM Cross
Molecular and cellular biology 25 (21), 9586-9594, 2005
1072005
Two thymidine hydroxylases differentially regulate the formation of glucosylated DNA at regions flanking polymerase II polycistronic transcription units throughout the genome …
LJ Cliffe, TN Siegel, M Marshall, GAM Cross, R Sabatini
Nucleic acids research 38 (12), 3923-3935, 2010
992010
Histone H3 trimethylated at lysine 4 is enriched at probable transcription start sites in Trypanosoma brucei
JR Wright, TN Siegel, GAM Cross
Molecular and biochemical parasitology 172 (2), 141-144, 2010
982010
Analysis of the Trypanosoma brucei cell cycle by quantitative DAPI imaging
TN Siegel, DR Hekstra, GAM Cross
Molecular and biochemical parasitology 160 (2), 171-174, 2008
972008
Exonuclease-mediated degradation of nascent RNA silences genes linked to severe malaria
Q Zhang, TN Siegel, RM Martins, F Wang, J Cao, Q Gao, X Cheng, ...
Nature 513 (7518), 431-435, 2014
862014
Two essential MYST‐family proteins display distinct roles in histone H4K10 acetylation and telomeric silencing in trypanosomes
T Kawahara, TN Siegel, AK Ingram, S Alsford, GAM Cross, D Horn
Molecular microbiology 69 (4), 1054-1068, 2008
852008
GT‐rich promoters can drive RNA pol II transcription and deposition of H2A. Z in African trypanosomes
C Wedel, KU Förstner, R Derr, TN Siegel
The EMBO journal 36 (17), 2581-2594, 2017
842017
Regulation of transcription termination by glucosylated hydroxymethyluracil, base J, in Leishmania major and Trypanosoma brucei
D Reynolds, L Cliffe, KU Förstner, CC Hon, TN Siegel, R Sabatini
Nucleic acids research 42 (15), 9717-9729, 2014
832014
PfAlbas constitute a new eukaryotic DNA/RNA-binding protein family in malaria parasites
A Chêne, SS Vembar, L Rivière, JJ Lopez-Rubio, A Claes, TN Siegel, ...
Nucleic acids research 40 (7), 3066-3077, 2012
792012
Novel insights into RNP granules by employing the trypanosome's microtubule skeleton as a molecular sieve
M Fritz, J Vanselow, N Sauer, S Lamer, C Goos, TN Siegel, I Subota, ...
Nucleic acids research 43 (16), 8013-8032, 2015
772015
Acetylation of histone H4K4 is cell cycle regulated and mediated by HAT3 in Trypanosoma brucei
TN Siegel, T Kawahara, JA DeGrasse, CJ Janzen, D Horn, GAM Cross
Molecular microbiology 67 (4), 762-771, 2008
702008
Efficient and specific oligo-based depletion of rRNA
AJ Kraus, BG Brink, TN Siegel
Scientific reports 9 (1), 12281, 2019
642019
Histone H3 Variant Regulates RNA Polymerase II Transcription Termination and Dual Strand Transcription of siRNA Loci in Trypanosoma brucei
D Reynolds, BT Hofmeister, L Cliffe, M Alabady, TN Siegel, RJ Schmitz, ...
PLoS genetics 12 (1), e1005758, 2016
642016
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