Thbs1 induces lethal cardiac atrophy through PERK-ATF4 regulated autophagy D Vanhoutte, TG Schips, A Vo, KM Grimes, TA Baldwin, MJ Brody, ... Nature Communications 12 (1), 3928, 2021 | 81 | 2021 |
Age-related changes in the proteostasis network in the brain of the naked mole-rat: Implications promoting healthy longevity JC Triplett, A Tramutola, A Swomley, J Kirk, K Grimes, K Lewis, M Orr, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1852 (10 …, 2015 | 75 | 2015 |
ERK1/2 signaling induces skeletal muscle slow fiber-type switching and reduces muscular dystrophy disease severity JG Boyer, V Prasad, T Song, D Lee, X Fu, KM Grimes, MA Sargent, ... JCI insight 4 (10), 2019 | 68 | 2019 |
Walking the oxidative stress tightrope: a perspective from the naked mole-rat, the longest-living rodent KA Rodriguez, E Wywial, VI Perez, AJ Lambert, YH Edrey, KN Lewis, ... Current pharmaceutical design 17 (22), 2290, 2011 | 65 | 2011 |
And the beat goes on: maintained cardiovascular function during aging in the longest-lived rodent, the naked mole-rat KM Grimes, AK Reddy, ML Lindsey, R Buffenstein American Journal of Physiology-Heart and Circulatory Physiology 307 (3 …, 2014 | 56 | 2014 |
MCUb induction protects the heart from postischemic remodeling J Huo, S Lu, JQ Kwong, MJ Bround, KM Grimes, MA Sargent, ME Brown, ... Circulation research 127 (3), 379-390, 2020 | 55 | 2020 |
Getting to the heart of the matter: age-related changes in diastolic heart function in the longest-lived rodent, the naked mole rat KM Grimes, ML Lindsey, JAL Gelfond, R Buffenstein Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2012 | 48 | 2012 |
TGFBI functions similar to periostin but is uniquely dispensable during cardiac injury JA Schwanekamp, A Lorts, MA Sargent, AJ York, KM Grimes, ... PloS one 12 (7), e0181945, 2017 | 43 | 2017 |
Cardiac function of the naked mole-rat: ecophysiological responses to working underground KM Grimes, A Voorhees, YA Chiao, HC Han, ML Lindsey, R Buffenstein American Journal of Physiology-Heart and Circulatory Physiology 306 (5 …, 2014 | 43 | 2014 |
Overlapping and differential functions of ATF6α versus ATF6β in the mouse heart RN Correll, KM Grimes, V Prasad, JM Lynch, H Khalil, JD Molkentin Scientific reports 9 (1), 2059, 2019 | 35 | 2019 |
Probing pedomorphy and prolonged lifespan in naked mole-rats and dwarf mice R Buffenstein, KN Lewis, PA Gibney, V Narayan, KM Grimes, M Smith, ... Physiology 35 (2), 96-111, 2020 | 31 | 2020 |
Supporting the heart: Functions of the cardiomyocyte's non-sarcomeric cytoskeleton KM Grimes, V Prasad, JW McNamara Journal of molecular and cellular cardiology 131, 187-196, 2019 | 29 | 2019 |
The naked mole-rat exhibits an unusual cardiac myofilament protein profile providing new insights into heart function of this naturally subterranean rodent KM Grimes, DY Barefield, M Kumar, JW McNamara, ST Weintraub, ... Pflügers Archiv-European Journal of Physiology 469, 1603-1613, 2017 | 26 | 2017 |
Rpl3l gene deletion in mice reduces heart weight over time KM Grimes, V Prasad, J Huo, Y Kuwabara, D Vanhoutte, TA Baldwin, ... Frontiers in Physiology 14, 30, 2023 | 4 | 2023 |
Basic Cardiovascular Sciences Scientific Sessions 2018: Innovating in Cardiovascular Research JW McNamara, KM Grimes, S Sadayappan Circulation Research 123 (9), 1024-1029, 2018 | 4 | 2018 |
Pre-B-cell Leukemia Homeobox Interacting Protein 1 is a Novel Regulator of Growth Signaling in the Heart KM Grimes, A Pyo, JD Molkentin Circulation research 125 (Suppl_1), A918-A918, 2019 | 1 | 2019 |
Cardiac function in an extraordinarily long-lived rodent, the naked mole-rat KM Grimes, YA Chiao, ML Lindsey, R Buffenstein Circulation 126 (suppl_21), A9857-A9857, 2012 | 1 | 2012 |
Exploring MCUb Function in the Heart and Its Role in Ischemia Reperfusion Injury J Huo, K Grimes, M Sargent, A York, J Kwong, J Molkentin Circulation Research 125 (Suppl_1), A546-A546, 2019 | | 2019 |
Identifying Downstream Effectors of the Extracellular Signal-related Kinase 1/2-controlled Directional Growth Response in Cardiomyocytes KM Grimes, M Maillet, JD Molkentin Circulation Research 123 (Suppl_1), A306-A306, 2018 | | 2018 |
MAINTENANCE OF GLUTATHIONE REDOX STATUS IN THE NAKED MOLE-RAT HEART UNDER CONDITIONS OF HIGH OXIDATIVE STRESS KM Grimes, R Buffenstein GERONTOLOGIST 55, 163-164, 2015 | | 2015 |