| PPARα is essential for retinal lipid metabolism and neuronal survival EA Pearsall, R Cheng, K Zhou, Y Takahashi, HG Matlock, SS Vadvalkar, ... BMC biology 15, 1-14, 2017 | 44 | 2017 |
| Impaired rhodopsin generation in the rat model of diabetic retinopathy VV Malechka, G Moiseyev, Y Takahashi, Y Shin, J Ma The American journal of pathology 187 (10), 2222-2231, 2017 | 42 | 2017 |
| Receptor heterodimerization as a novel mechanism for the regulation of Wnt/β-catenin signaling K Lee, Y Shin, R Cheng, K Park, Y Hu, J McBride, X He, Y Takahashi, ... Journal of cell science 127 (22), 4857-4869, 2014 | 36 | 2014 |
| A dominant mutation in Rpe65, D477G, delays dark adaptation and disturbs the visual cycle in the mutant knock-in mice Y Shin, G Moiseyev, D Chakraborty, J Ma The American journal of pathology 187 (3), 517-527, 2017 | 29 | 2017 |
| A novel RPE65 inhibitor CU239 suppresses visual cycle and prevents retinal degeneration Y Shin, G Moiseyev, K Petrukhin, CL Cioffi, P Muthuraman, Y Takahashi, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1864 (7 …, 2018 | 23 | 2018 |
| Transgenic mice over-expressing RBP4 have RBP4-dependent and light-independent retinal degeneration M Du, E Phelps, MJ Balangue, A Dockins, G Moiseyev, Y Shin, S Kane, ... Investigative ophthalmology & visual science 58 (10), 4375-4383, 2017 | 14 | 2017 |
| Anti-angiogenic effect of a humanized antibody blocking the Wnt/β-catenin signaling pathway F Qiu, Y Shin, D Chen, R Cheng, Q Chen, K Zhou, JW Larrick, ... Microvascular research 119, 29-37, 2018 | 10 | 2018 |
| Evolution of a 4-benzyloxy-benzylamino chemotype to provide efficacious, potent, and isoform selective PPARα agonists as leads for retinal disorders X Dou, D Nath, H Shin, E Nurmemmedov, PC Bourne, JX Ma, ... Journal of medicinal chemistry 63 (6), 2854-2876, 2020 | 9 | 2020 |
| Structure-guided evolution of a 2-phenyl-4-carboxyquinoline chemotype into PPARα selective agonists: New leads for oculovascular conditions XZ Dou, D Nath, Y Shin, JX Ma, AS Duerfeldt Bioorganic & medicinal chemistry letters 28 (16), 2717-2722, 2018 | 9 | 2018 |
| Soluble very low‐density lipoprotein receptor (sVLDLR) inhibits fibrosis in neovascular age‐related macular degeneration X Ma, Y Takahashi, W Wu, J Chen, M Dehdarani, W Liang, YH Shin, ... The FASEB Journal 35 (12), 2021 | 7 | 2021 |
| The interplay of environmental luminance and genetics in the retinal dystrophy induced by the dominant RPE65 mutation W Wu, Y Takahashi, HY Shin, X Ma, G Moiseyev, JX Ma Proceedings of the National Academy of Sciences 119 (11), e2115202119, 2022 | 4 | 2022 |
| Fenofibrate is a competitive inhibitor of the RPE65 isomerase GP Moiseyev, Y Shin, Y Takahashi, JXJ Ma Investigative Ophthalmology & Visual Science 57 (12), 1749-1749, 2016 | 1 | 2016 |
| A Novel non-Retinoid RPE65 Inhibitor CU239 Prevents Light-Induced Degeneration of the Mouse Retina through Slowing of the Visual Cycle GP Moiseyev, Y Shin, Y Takahashi, K Petrukhin, JXJ Ma Investigative Ophthalmology & Visual Science 59 (9), 5330-5330, 2018 | | 2018 |
| Design, synthesis, and bioactivity of small molecule leads for the treatment of oculovascular diseases X Dou, D Nath, G Deng, YH Shin, JX Ma, A Duerfeldt ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 255, 2018 | | 2018 |
| D477G dominant mutation in RPE65 leads to decreased 11-cis-retinal generation and delayed dark-adaptation in knock-in mouse model of retinitis pigmentosa GP Moiseyev, Y Shin, D Charkraborty, JXJ Ma Investigative Ophthalmology & Visual Science 58 (8), 590-590, 2017 | | 2017 |
| Impaired Retinoid Visual Cycle in Diabetic Retinopathy V Malechka, GP Moiseyev, Y Takahashi, Y Shin, JXJ Ma Investigative Ophthalmology & Visual Science 58 (8), 5226-5226, 2017 | | 2017 |
| RPE-specific knock-out of Retinol Dehydrogenase 10 altered retinoid profile Y Shin, GP Moiseyev, KM Farjo, Y Takahashi, JXJ Ma Investigative Ophthalmology & Visual Science 57 (12), 3621-3621, 2016 | | 2016 |
| Inhibitory Effects of Monoclonial Antibodies Blocking the Wnt Pathway on Experimental Corneal Neovascularization F Qiu, Y Shin, D Chen, G Deng, JXJ Ma Investigative Ophthalmology & Visual Science 57 (12), 5021-5021, 2016 | | 2016 |
| Therapeutic Potential of Monoclonal Antibodies Blocking the Wnt Pathway in Corneal Neovascularization F Qiu, Y Shin, D Chen, G Deng, JXJ Ma Investigative Ophthalmology & Visual Science 56 (7), 4513-4513, 2015 | | 2015 |
| Heterodimerization of VLDLR and LRP6: A novel mechanism for the inhibition of the Wnt/β-catenin pathway. Y Shin, K Lee, R Cheng, K Park, Y Hu, Y Takahashi, J Ma Investigative Ophthalmology & Visual Science 56 (7), 5443-5443, 2015 | | 2015 |
