Flexible use of nuclear import pathways by HIV-1 KE Lee, Z Ambrose, TD Martin, I Oztop, A Mulky, JG Julias, N Vandegraaff, ... Cell host & microbe 7 (3), 221-233, 2010 | 532 | 2010 |
HIV-1 uncoating: connection to nuclear entry and regulation by host proteins Z Ambrose, C Aiken Virology 454, 371-379, 2014 | 252 | 2014 |
A macaque model of HIV-1 infection T Hatziioannou, Z Ambrose, NPY Chung, M Piatak Jr, F Yuan, CM Trubey, ... Proceedings of the National Academy of Sciences 106 (11), 4425-4429, 2009 | 205 | 2009 |
HIV/AIDS: in search of an animal model Z Ambrose, VN KewalRamani, PD Bieniasz, T Hatziioannou Trends in biotechnology 25 (8), 333-337, 2007 | 128 | 2007 |
Human immunodeficiency virus type 1 capsid mutation N74D alters cyclophilin A dependence and impairs macrophage infection Z Ambrose, KE Lee, J Ndjomou, H Xu, I Oztop, J Matous, T Takemura, ... Journal of virology 86 (8), 4708-4714, 2012 | 110 | 2012 |
Direct visualization of HIV-1 with correlative live-cell microscopy and cryo-electron tomography S Jun, D Ke, K Debiec, G Zhao, X Meng, Z Ambrose, GA Gibson, ... Structure 19 (11), 1573-1581, 2011 | 103 | 2011 |
Evidence for biphasic uncoating during HIV-1 infection from a novel imaging assay H Xu, T Franks, G Gibson, K Huber, N Rahm, CS De Castillia, J Luban, ... Retrovirology 10, 1-16, 2013 | 100 | 2013 |
In vitro characterization of a simian immunodeficiency virus-human immunodeficiency virus (HIV) chimera expressing HIV type 1 reverse transcriptase to study antiviral … Z Ambrose, V Boltz, S Palmer, JM Coffin, SH Hughes, VN KewalRamani Journal of virology 78 (24), 13553-13561, 2004 | 81 | 2004 |
Suppression of viremia and evolution of human immunodeficiency virus type 1 drug resistance in a macaque model for antiretroviral therapy Z Ambrose, S Palmer, VF Boltz, M Kearney, K Larsen, P Polacino, ... Journal of virology 81 (22), 12145-12155, 2007 | 62 | 2007 |
Interferon-inducible CD169/Siglec1 attenuates anti-HIV-1 effects of alpha interferon H Akiyama, NGP Ramirez, G Gibson, C Kline, S Watkins, Z Ambrose, ... Journal of virology 91 (21), 10.1128/jvi. 00972-17, 2017 | 54 | 2017 |
Rilpivirine and doravirine have complementary efficacies against NNRTI-resistant HIV-1 mutants SJ Smith, GT Pauly, A Akram, K Melody, Z Ambrose, JP Schneider, ... JAIDS Journal of Acquired Immune Deficiency Syndromes 72 (5), 485-491, 2016 | 54 | 2016 |
Establishment and Reversal of HIV-1 Latency in Naive and Central Memory CD4+ T Cells In Vitro JM Zerbato, E Serrao, G Lenzi, B Kim, Z Ambrose, SC Watkins, ... Journal of virology 90 (18), 8059-8073, 2016 | 50 | 2016 |
Persistence of viral reservoirs in multiple tissues after antiretroviral therapy suppression in a macaque RT-SHIV model C Kline, J Ndjomou, T Franks, R Kiser, V Coalter, J Smedley, M Piatak Jr, ... PloS one 8 (12), e84275, 2013 | 50 | 2013 |
Permeability of the HIV-1 capsid to metabolites modulates viral DNA synthesis C Xu, DK Fischer, S Rankovic, W Li, RA Dick, B Runge, R Zadorozhnyi, ... PLoS biology 18 (12), e3001015, 2020 | 49 | 2020 |
Genetic diversity of simian immunodeficiency virus encoding HIV-1 reverse transcriptase persists in macaques despite antiretroviral therapy M Kearney, J Spindler, W Shao, F Maldarelli, S Palmer, SL Hu, JD Lifson, ... Journal of virology 85 (2), 1067-1076, 2011 | 45 | 2011 |
SIV and Mycobacterium tuberculosis synergy within the granuloma accelerates the reactivation pattern of latent tuberculosis CR Diedrich, T Rutledge, P Maiello, TM Baranowski, AG White, HJ Borish, ... PLoS pathogens 16 (7), e1008413, 2020 | 44 | 2020 |
Truncated CPSF6 forms higher-order complexes that bind and disrupt HIV-1 capsid J Ning, Z Zhong, DK Fischer, G Harris, SC Watkins, Z Ambrose, P Zhang Journal of virology 92 (13), 10.1128/jvi. 00368-18, 2018 | 40 | 2018 |
A novel phenotype links HIV-1 capsid stability to cGAS-mediated DNA sensing MA Siddiqui, A Saito, UD Halambage, D Ferhadian, DK Fischer, ... Journal of virology 93 (16), 10.1128/jvi. 00706-19, 2019 | 38 | 2019 |
The nucleoside analogs 4′ C-methyl thymidine and 4′ C-ethyl thymidine block DNA synthesis by wild-type HIV-1 RT and excision proficient NRTI resistant RT variants PL Boyer, JG Julias, Z Ambrose, MA Siddiqui, VE Marquez, SH Hughes Journal of molecular biology 371 (4), 873-882, 2007 | 34 | 2007 |
Cytoplasmic CPSF6 regulates HIV-1 capsid trafficking and infection in a cyclophilin A-dependent manner Z Zhong, J Ning, EA Boggs, S Jang, C Wallace, C Telmer, MP Bruchez, ... MBio 12 (2), 10.1128/mbio. 03142-20, 2021 | 32 | 2021 |