Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor V Rothhammer, ID Mascanfroni, L Bunse, MC Takenaka, JE Kenison, ... Nature medicine 22 (6), 586-597, 2016 | 1226 | 2016 |
The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence JI Alvarez, A Dodelet-Devillers, H Kebir, I Ifergan, PJ Fabre, S Terouz, ... Science 334 (6063), 1727-1731, 2011 | 857 | 2011 |
Microglial control of astrocytes in response to microbial metabolites V Rothhammer, DM Borucki, EC Tjon, MC Takenaka, CC Chao, ... Nature 557 (7707), 724-728, 2018 | 851 | 2018 |
Preferential recruitment of interferon‐γ–expressing TH17 cells in multiple sclerosis H Kebir, I Ifergan, JI Alvarez, M Bernard, J Poirier, N Arbour, P Duquette, ... Annals of Neurology: Official Journal of the American Neurological …, 2009 | 660 | 2009 |
Glial influence on the blood brain barrier JI Alvarez, T Katayama, A Prat Glia 61 (12), 1939-1958, 2013 | 602 | 2013 |
How do immune cells overcome the blood–brain barrier in multiple sclerosis? C Larochelle, JI Alvarez, A Prat FEBS letters 585 (23), 3770-3780, 2011 | 561 | 2011 |
Regulation of astrocyte activation by glycolipids drives chronic CNS inflammation L Mayo, SA Trauger, M Blain, M Nadeau, B Patel, JI Alvarez, ... Nature medicine 20 (10), 1147-1156, 2014 | 440 | 2014 |
Disruption of central nervous system barriers in multiple sclerosis JI Alvarez, R Cayrol, A Prat Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1812 (2), 252-264, 2011 | 397 | 2011 |
Immunologic privilege in the central nervous system and the blood–brain barrier LL Muldoon, JI Alvarez, DJ Begley, RJ Boado, GJ Del Zoppo, ND Doolittle, ... Journal of Cerebral Blood Flow & Metabolism 33 (1), 13-21, 2013 | 346 | 2013 |
leucocyte–endothelial cell crosstalk at the blood–brain barrier: a prerequisite for successful immune cell entry to the brain J Greenwood, SJ Heasman, JI Alvarez, A Prat, R Lyck, B Engelhardt Neuropathology and applied neurobiology 37 (1), 24-39, 2011 | 288 | 2011 |
Neutrophils mediate blood–spinal cord barrier disruption in demyelinating neuroinflammatory diseases B Aubé, SA Lévesque, A Paré, E Chamma, H Kébir, R Gorina, ... The Journal of Immunology 193 (5), 2438-2454, 2014 | 236 | 2014 |
Brain granulomas in neurocysticercosis patients are associated with a Th1 and Th2 profile BI Restrepo, JI Alvarez, JA Castaño, LF Arias, M Restrepo, J Trujillo, ... Infection and Immunity 69 (7), 4554-4560, 2001 | 172 | 2001 |
Myeloid cell transmigration across the CNS vasculature triggers IL-1β–driven neuroinflammation during autoimmune encephalomyelitis in mice SA Lévesque, A Paré, B Mailhot, V Bellver-Landete, H Kébir, MA Lécuyer, ... Journal of Experimental Medicine 213 (6), 929-949, 2016 | 170 | 2016 |
Role of ninjurin‐1 in the migration of myeloid cells to central nervous system inflammatory lesions I Ifergan, H Kebir, S Terouz, JI Alvarez, MA Lécuyer, S Gendron, ... Annals of neurology 70 (5), 751-763, 2011 | 169 | 2011 |
Netrin 1 regulates blood–brain barrier function and neuroinflammation C Podjaski, JI Alvarez, L Bourbonniere, S Larouche, S Terouz, JM Bin, ... Brain 138 (6), 1598-1612, 2015 | 160 | 2015 |
Focal disturbances in the blood–brain barrier are associated with formation of neuroinflammatory lesions JI Alvarez, O Saint-Laurent, A Godschalk, S Terouz, C Briels, S Larouche, ... Neurobiology of disease 74, 14-24, 2015 | 159 | 2015 |
Melanoma cell adhesion molecule identifies encephalitogenic T lymphocytes and promotes their recruitment to the central nervous system C Larochelle, R Cayrol, H Kebir, JI Alvarez, MA Lecuyer, I Ifergan, E Viel, ... Brain 135 (10), 2906-2924, 2012 | 159 | 2012 |
Central nervous system recruitment of effector memory CD8+ T lymphocytes during neuroinflammation is dependent on α4 integrin I Ifergan, H Kebir, JI Alvarez, G Marceau, M Bernard, L Bourbonniere, ... Brain 134 (12), 3560-3577, 2011 | 152 | 2011 |
Glial-endothelial crosstalk regulates blood–brain barrier function L Cheslow, JI Alvarez Current opinion in pharmacology 26, 39-46, 2016 | 121 | 2016 |
IL-10-dependent Tr1 cells attenuate astrocyte activation and ameliorate chronic central nervous system inflammation L Mayo, APD Cunha, A Madi, V Beynon, Z Yang, JI Alvarez, A Prat, ... Brain 139 (7), 1939-1957, 2016 | 109 | 2016 |