Coordinated regulation of protein synthesis and degradation by mTORC1 Y Zhang, J Nicholatos, JR Dreier, SJH Ricoult, SB Widenmaier, ... Nature 513 (7518), 440-443, 2014 | 365 | 2014 |
Glucose‐dependent insulinotropic polypeptide (gastric inhibitory polypeptide; GIP) CHS McIntosh, S Widenmaier, SJ Kim Vitamins & Hormones 80, 409-471, 2009 | 231 | 2009 |
NRF1 is an ER membrane sensor that is central to cholesterol homeostasis SB Widenmaier, NA Snyder, TB Nguyen, A Arduini, GY Lee, AP Arruda, ... Cell 171 (5), 1094-1109. e15, 2017 | 196 | 2017 |
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity A Bartelt, SB Widenmaier, C Schlein, K Johann, RLS Goncalves, K Eguchi, ... Nature medicine 24 (3), 292-303, 2018 | 165 | 2018 |
Glucose-Dependent Insulinotropic Polypeptide-Mediated Up-Regulation of β-Cell Antiapoptotic Bcl-2 Gene Expression Is Coordinated by Cyclic AMP (cAMP … SJ Kim, C Nian, S Widenmaier, CHS McIntosh Molecular and cellular biology 28 (5), 1644-1656, 2008 | 152 | 2008 |
A GIP receptor agonist exhibits β-cell anti-apoptotic actions in rat models of diabetes resulting in improved β-cell function and glycemic control SB Widenmaier, SJ Kim, GK Yang, T De Los Reyes, C Nian, A Asadi, ... PloS one 5 (3), e9590, 2010 | 121 | 2010 |
Suppression of p38 MAPK and JNK via Akt-mediated inhibition of apoptosis signal-regulating kinase 1 constitutes a core component of the β-cell pro-survival effects of glucose … SB Widenmaier, Z Ao, SJ Kim, G Warnock, CHS McIntosh Journal of Biological Chemistry 284 (44), 30372-30382, 2009 | 111 | 2009 |
Bcl-2 and Bcl-xL suppress glucose signaling in pancreatic β-cells DS Luciani, SA White, SB Widenmaier, VV Saran, F Taghizadeh, X Hu, ... Diabetes 62 (1), 170-182, 2013 | 84 | 2013 |
Glucose‐dependent insulinotropic polypeptide signaling in pancreatic β‐cells and adipocytes CHS McIntosh, S Widenmaier, SJ Kim Journal of diabetes investigation 3 (2), 96-106, 2012 | 54 | 2012 |
Pleiotropic actions of the incretin hormones CHS McIntosh, S Widenmaier, SJ Kim Vitamins & Hormones 84, 21-79, 2010 | 47 | 2010 |
Pancreatic β-cell prosurvival effects of the incretin hormones involve post-translational modification of Kv2. 1 delayed rectifier channels SJ Kim, SB Widenmaier, WS Choi, C Nian, Z Ao, G Warnock, ... Cell Death & Differentiation 19 (2), 333-344, 2012 | 40 | 2012 |
Noncanonical activation of Akt/protein kinase B in β-cells by the incretin hormone glucose-dependent insulinotropic polypeptide SB Widenmaier, AV Sampaio, TM Underhill, CHS McIntosh Journal of biological chemistry 284 (16), 10764-10773, 2009 | 40 | 2009 |
Only iron-limited cells of the cyanobacterium Anabaena flos-aquae inhibit growth of the green alga Chlamydomonas reinhardtii CJ Matz, MR Christensen, AD Bone, CD Gress, SB Widenmaier, ... Canadian journal of botany 82 (4), 436-442, 2004 | 22 | 2004 |
Proteostasis in thermogenesis and obesity A Bartelt, SB Widenmaier Biological Chemistry 401 (9), 1019-1030, 2020 | 19 | 2020 |
Complementary gene regulation by NRF1 and NRF2 protects against hepatic cholesterol overload MG Akl, L Li, R Baccetto, S Phanse, Q Zhang, MJ Trites, S McDonald, ... Cell reports 42 (4), 2023 | 11 | 2023 |
Immune cell intolerance for excess cholesterol SB Widenmaier, GS Hotamışlıgil Immunity 45 (6), 1186-1188, 2016 | 6 | 2016 |
HDL functionality is dependent on hepatocyte stress defense factors Nrf1 and Nrf2 MJ Trites, BM Stebbings, H Aoki, S Phanse, MG Akl, L Li, M Babu, ... Frontiers in Physiology 14, 1212785, 2023 | 4 | 2023 |
Immunometabolic factors contributing to obesity-linked hepatocellular carcinoma MG Akl, SB Widenmaier Frontiers in Cell and Developmental Biology 10, 1089124, 2023 | 3 | 2023 |
Euglycemia is affected by stress defense factor hepatocyte NRF1, but not NRF2 MG Akl, R Baccetto, BM Stebbings, L Li, SB Widenmaier Biochemical and Biophysical Research Communications 668, 96-103, 2023 | 2 | 2023 |
Anti-AP2 antibodies and antigen binding agents to treat metabolic disorders GS Hotamisligil, MF Burak, F Engin, SB Widenmaier, EH Roberts, ... US Patent 11,014,979, 2021 | 2 | 2021 |