Mode of action of natural and synthetic drugs against Trypanosoma cruzi and their interaction with the mammalian host JD Maya, BK Cassels, P Iturriaga-Vásquez, J Ferreira, M Faúndez, ... Comparative Biochemistry and Physiology Part A: Molecular & Integrative …, 2007 | 506 | 2007 |
Molecular determinants for competitive inhibition of α4β2 nicotinic acetylcholine receptors P Iturriaga-Vásquez, A Carbone, O García-Beltran, PD Livingstone, ... Molecular Pharmacology 78 (3), 366-375, 2010 | 56 | 2010 |
2-Arylthiomorpholine derivatives as potent and selective monoamine oxidase B inhibitors S Lühr, M Vilches-Herrera, A Fierro, RR Ramsay, DE Edmondson, ... Bioorganic & medicinal chemistry 18 (4), 1388-1395, 2010 | 48 | 2010 |
Naphthylisopropylamine and N-benzylamphetamine derivatives as monoamine oxidase inhibitors M Vilches-Herrera, J Miranda-Sepúlveda, M Rebolledo-Fuentes, A Fierro, ... Bioorganic & medicinal chemistry 17 (6), 2452-2460, 2009 | 41 | 2009 |
Rhodolirium andicola: a new renewable source of alkaloids with acetylcholinesterase inhibitory activity, a study from nature to molecular docking F Moraga-Nicolás, C Jara, R Godoy, P Iturriaga-Vásquez, H Venthur, ... Revista Brasileira de Farmacognosia 28, 34-43, 2018 | 40 | 2018 |
C3-halogenation of cytisine generates potent and efficacious nicotinic receptor agonists JA Abin-Carriquiry, MH Voutilainen, J Barik, BK Cassels, ... European journal of pharmacology 536 (1-2), 1-11, 2006 | 37 | 2006 |
Synthesis, binding assays, cytotoxic activity and docking studies of benzimidazole and benzothiophene derivatives with selective affinity for the CB2 cannabinoid receptor J Romero-Parra, J Mella-Raipán, V Palmieri, M Allarà, MJ Torres, ... European Journal of Medicinal Chemistry 124, 17-35, 2016 | 35 | 2016 |
Role of the cys loop and transmembrane domain in the allosteric modulation of α4β2 nicotinic acetylcholine receptors C Alcaino, M Musgaard, T Minguez, S Mazzaferro, M Faundez, ... Journal of Biological Chemistry 292 (2), 551-562, 2017 | 32 | 2017 |
Monoamine oxidase inhibition in the light of new structural data M Reyes-Parada, A Fierro, P Iturriaga-Vásquez, BK Cassels Current Enzyme Inhibition 1 (1), 85-95, 2005 | 32 | 2005 |
Multiple binding sites in the nicotinic acetylcholine receptors: An opportunity for polypharmacolgy P Iturriaga-Vásquez, J Alzate-Morales, I Bermudez, R Varas, ... Pharmacological Research 101, 9-17, 2015 | 31 | 2015 |
Characterization of a Novel Drosophila SERT Mutant: Insights on the Contribution of the Serotonin Neural System to Behaviors S Hidalgo, D Molina-Mateo, P Escobedo, RV Zárate, E Fritz, A Fierro, ... ACS chemical neuroscience 8 (10), 2168-2179, 2017 | 29 | 2017 |
Monoamine oxidase inhibitory properties of optical isomers and N-substituted derivatives of 4-methylthioamphetamine C Hurtado Guzmán, A Fierro, P Iturriaga-Vásquez, S Sepúlveda Boza, ... Taylor & Francis Ltd, 2003 | 28 | 2003 |
Amphetamine derivatives as monoamine oxidase inhibitors M Reyes-Parada, P Iturriaga-Vasquez, BK Cassels Frontiers in pharmacology 10, 497984, 2020 | 27 | 2020 |
Neonicotinic analogues: Selective antagonists for α4β2 nicotinic acetylcholine receptors M Faundez-Parraguez, N Farias-Rabelo, JP Gonzalez-Gutierrez, ... Bioorganic & medicinal chemistry 21 (10), 2687-2694, 2013 | 26 | 2013 |
Simplified tetrandrine congeners as possible antihypertensive agents with a dual mechanism of action P Iturriaga-Vásquez, R Miquel, MD Ivorra, MP D'Ocon, BK Cassels Journal of natural products 66 (7), 954-957, 2003 | 25 | 2003 |
Design, synthesis, binding and docking-based 3D-QSAR studies of 2-pyridylbenzimidazoles—A new family of high affinity CB1 cannabinoid ligands JA Mella-Raipán, CF Lagos, G Recabarren-Gajardo, C Espinosa-Bustos, ... Molecules 18 (4), 3972-4001, 2013 | 23 | 2013 |
Synthesis, in vitro evaluation and molecular docking of a new class of indolylpropyl benzamidopiperazines as dual AChE and SERT ligands for Alzheimer’s disease J Rodriguez-Lavado, C Gallardo-Garrido, M Mallea, V Bustos, R Osorio, ... European Journal of Medicinal Chemistry 198, 112368, 2020 | 22 | 2020 |
Electrophysiological characterization of nicotinic acetylcholine receptors in cat petrosal ganglion neurons in culture: effects of cytisine and its bromo derivatives R Varas, V Valdés, P Iturriaga-Vásquez, BK Cassels, R Iturriaga, ... Brain research 1072 (1), 72-78, 2006 | 21 | 2006 |
Aporphine metho salts as neuronal nicotinic acetylcholine receptor blockers P Iturriaga-Vásquez, EG Pérez, EY Slater, I Bermudez, BK Cassels Bioorganic & medicinal chemistry 15 (10), 3368-3372, 2007 | 19 | 2007 |
Zebrafish: a model for behavioral pharmacology P Iturriaga-Vásquez, F Osorio, S Riquelme, S Castro, R Herzog Farmacología de Chile 5, 27-32, 2012 | 18 | 2012 |