| Pharmacological blockade of the EP3 prostaglandin E2 receptor in the setting of type 2 diabetes enhances β-cell proliferation and identity and relieves oxidative damage KJ Bosma, SR Andrei, LS Katz, AA Smith, JC Dunn, VF Ricciardi, ... Molecular Metabolism 54, 101347, 2021 | 25 | 2021 |
| Glucose-6-phosphatase catalytic subunit 2 negatively regulates glucose oxidation and insulin secretion in pancreatic β-cells M Rahim, AY Nakhe, DR Banerjee, EM Overway, KJ Bosma, JC Rosch, ... Journal of Biological Chemistry 298 (4), 2022 | 14 | 2022 |
| Nonsynonymous single-nucleotide polymorphisms in the G6PC2 gene affect protein expression, enzyme activity, and fasting blood glucose EM Overway, KJ Bosma, DP Claxton, JK Oeser, K Singh, LB Breidenbach, ... Journal of Biological Chemistry 298 (2), 2022 | 14 | 2022 |
| Biophysical and functional properties of purified glucose-6-phosphatase catalytic subunit 1 DP Claxton, EM Overway, JK Oeser, RM O'Brien, HS Mchaourab Journal of Biological Chemistry 298 (1), 2022 | 14 | 2022 |
| Integrative analysis of pathogenic variants in glucose-6-phosphatase based on an AlphaFold2 model M Sinclair, RA Stein, JH Sheehan, EM Hawes, RM O’Brien, E Tajkhorshid, ... PNAS nexus 3 (2), pgae036, 2024 | 3 | 2024 |
| Identification of structural motifs critical for human G6PC2 function informed by sequence analysis and an AlphaFold2-predicted model EM Hawes, DP Claxton, JK Oeser, RM O’Brien Bioscience Reports 44 (1), BSR20231851, 2024 | 3 | 2024 |
| Biochemical and metabolic characterization of a G6PC2 inhibitor EM Hawes, M Rahim, Z Haratipour, AR Orun, ML O'Rourke, JK Oeser, ... Biochimie 222, 109-122, 2024 | 1 | 2024 |
| G6PC1 and G6PC2 influence G6P flux but not HSD11B1 activity EM Hawes, KA Boortz, JK Oeser, ML O’Rourke, RM O’Brien Journal of molecular endocrinology 71 (4), 2023 | 1 | 2023 |
| An Enhancer Within Abcb11 Regulates G6pc2 in C57BL/6 Mouse Pancreatic Islets MP Keller, EM Hawes, KL Schueler, DS Stapleton, KA Mitok, SP Simonett, ... Diabetes 72 (11), 1621-1628, 2023 | 1 | 2023 |
| Regulation of Glucose-6-Phosphatase Catalytic Subunit 2 (G6PC2) Expression and Activity EM Hawes | | 2024 |
Richard O'BrienProfessor of Molecular Physiology & Biophysics在 vanderbilt.edu 的电子邮件经过验证
Richard O'BrienProfessor of Molecular Physiology & Biophysics在 vanderbilt.edu 的电子邮件经过验证