Growth of triple-negative breast cancer cells relies upon coordinate autocrine expression of the proinflammatory cytokines IL-6 and IL-8 ZC Hartman, GM Poage, P Den Hollander, A Tsimelzon, J Hill, ... Cancer research 73 (11), 3470-3480, 2013 | 452 | 2013 |
Dynein light chain 1, a p21-activated kinase 1-interacting substrate, promotes cancerous phenotypes RK Vadlamudi, R Bagheri-Yarmand, Z Yang, S Balasenthil, D Nguyen, ... Cancer cell 5 (6), 575-585, 2004 | 238 | 2004 |
Targeted therapy for breast cancer prevention P Den Hollander, MI Savage, PH Brown Frontiers in oncology 3, 250, 2013 | 206 | 2013 |
Identification of EMT signaling cross-talk and gene regulatory networks by single-cell RNA sequencing AP Deshmukh, SV Vasaikar, K Tomczak, S Tripathi, P Den Hollander, ... Proceedings of the National Academy of Sciences 118 (19), e2102050118, 2021 | 171 | 2021 |
A sequence-level map of chromosomal breakpoints in the MCF-7 breast cancer cell line yields insights into the evolution of a cancer genome OA Hampton, P Den Hollander, CA Miller, DA Delgado, J Li, C Coarfa, ... Genome research 19 (2), 167-177, 2009 | 150 | 2009 |
MTA1, a transcriptional activator of breast cancer amplified sequence 3 AE Gururaj, RR Singh, SK Rayala, C Holm, P Den Hollander, H Zhang, ... Proceedings of the National Academy of Sciences 103 (17), 6670-6675, 2006 | 142 | 2006 |
EMTome: A resource for pan-cancer analysis of epithelial-mesenchymal transition genes and signatures SV Vasaikar, AP Deshmukh, P den Hollander, S Addanki, NA Kuburich, ... British journal of cancer 124 (1), 259-269, 2021 | 139 | 2021 |
GSK3β regulates epithelial-mesenchymal transition and cancer stem cell properties in triple-negative breast cancer GV Vijay, N Zhao, P Den Hollander, MJ Toneff, R Joseph, M Pietila, ... Breast Cancer Research 21, 1-14, 2019 | 135 | 2019 |
Cyclin D1 and p16 alterations in advanced premalignant lesions of the upper aerodigestive tract: role in response to chemoprevention and cancer development VA Papadimitrakopoulou, J Izzo, L Mao, J Keck, D Hamilton, DM Shin, ... Clinical Cancer Research 7 (10), 3127-3134, 2001 | 112 | 2001 |
Cyclin D1 genotype, response to biochemoprevention, and progression rate to upper aerodigestive tract cancer JG Izzo, VA Papadimitrakopoulou, DD Liu, PLC den Hollander, ... Journal of the National Cancer Institute 95 (3), 198-205, 2003 | 111 | 2003 |
Phosphatase PTP4A3 promotes triple-negative breast cancer growth and predicts poor patient survival P Den Hollander, K Rawls, A Tsimelzon, J Shepherd, A Mazumdar, J Hill, ... Cancer research 76 (7), 1942-1953, 2016 | 97 | 2016 |
Functional regulation of oestrogen receptor pathway by the dynein light chain 1 SK Rayala, P den Hollander, S Balasenthil, Z Yang, RR Broaddus, ... EMBO reports 6 (6), 538-544, 2005 | 88 | 2005 |
Essential role of KIBRA in co-activator function of dynein light chain 1 in mammalian cells SK Rayala, P Den Hollander, B Manavathi, AH Talukder, C Song, S Peng, ... Journal of Biological Chemistry 281 (28), 19092-19099, 2006 | 87 | 2006 |
Distinguishing mechanisms underlying EMT tristability D Jia, MK Jolly, SC Tripathi, P Den Hollander, B Huang, M Lu, M Celiktas, ... Cancer convergence 1, 1-19, 2017 | 82 | 2017 |
Vimentin and cytokeratin: Good alone, bad together NA Kuburich, P den Hollander, JT Pietz, SA Mani Seminars in cancer biology 86, 816-826, 2022 | 80 | 2022 |
Ciz1, a novel DNA-binding coactivator of the estrogen receptor α, confers hypersensitivity to estrogen action P Den Hollander, SK Rayala, D Coverley, R Kumar Cancer Research 66 (22), 11021-11029, 2006 | 80 | 2006 |
Mechanisms of cancer metastasis M Castaneda, P den Hollander, NA Kuburich, JM Rosen, SA Mani Seminars in cancer biology 87, 17-31, 2022 | 78 | 2022 |
Role of p38 MAP kinase in cancer stem cells and metastasis S Kudaravalli, P den Hollander, SA Mani Oncogene 41 (23), 3177-3185, 2022 | 69 | 2022 |
Dynein light chain 1 contributes to cell cycle progression by increasing cyclin-dependent kinase 2 activity in estrogen-stimulated cells P Den Hollander, R Kumar Cancer Research 66 (11), 5941-5949, 2006 | 62 | 2006 |
Phosphorylation of serine 367 of FOXC2 by p38 regulates ZEB1 and breast cancer metastasis, without impacting primary tumor growth SJ Werden, N Sphyris, TR Sarkar, AN Paranjape, AM LaBaff, JH Taube, ... Oncogene 35 (46), 5977-5988, 2016 | 60 | 2016 |