Interleukin‐1 blockade inhibits the acute inflammatory response in patients with ST‐segment–elevation myocardial infarction A Abbate, CR Trankle, LF Buckley, MJ Lipinski, D Appleton, D Kadariya, ... Journal of the American Heart Association 9 (5), e014941, 2020 | 190 | 2020 |
Airway surface liquid homeostasis in cystic fibrosis: pathophysiology and therapeutic targets IJ Haq, MA Gray, JP Garnett, C Ward, M Brodlie Thorax 71 (3), 284-287, 2016 | 187 | 2016 |
Metformin reduces airway glucose permeability and hyperglycaemia-induced Staphylococcus aureus load independently of effects on blood glucose JP Garnett, EH Baker, S Naik, JA Lindsay, GM Knight, S Gill, JS Tregoning, ... Thorax 68 (9), 835-845, 2013 | 119 | 2013 |
Novel role for pendrin in orchestrating bicarbonate secretion in cystic fibrosis transmembrane conductance regulator (CFTR)-expressing airway serous cells JP Garnett, E Hickman, R Burrows, P Hegyi, L Tiszlavicz, AW Cuthbert, ... Journal of Biological Chemistry 286 (47), 41069-41082, 2011 | 115 | 2011 |
Sweet talk: insights into the nature and importance of glucose transport in lung epithelium JP Garnett, EH Baker, DL Baines European Respiratory Journal 40 (5), 1269-1276, 2012 | 99 | 2012 |
Increased airway glucose increases airway bacterial load in hyperglycaemia SK Gill, K Hui, H Farne, JP Garnett, DL Baines, LSP Moore, AH Holmes, ... Scientific reports 6 (1), 27636, 2016 | 97 | 2016 |
Delayed induction of type I and III interferons mediates nasal epithelial cell permissiveness to SARS-CoV-2 CF Hatton, RA Botting, ME Dueñas, IJ Haq, B Verdon, BJ Thompson, ... Nature Communications 12 (1), 7092, 2021 | 79 | 2021 |
Proinflammatory mediators disrupt glucose homeostasis in airway surface liquid JP Garnett, TT Nguyen, JD Moffatt, ER Pelham, KK Kalsi, EH Baker, ... The Journal of Immunology 189 (1), 373-380, 2012 | 73 | 2012 |
Elevated paracellular glucose flux across cystic fibrosis airway epithelial monolayers is an important factor for Pseudomonas aeruginosa growth JP Garnett, MA Gray, R Tarran, M Brodlie, C Ward, EH Baker, DL Baines PloS one 8 (10), e76283, 2013 | 68 | 2013 |
Hyperglycaemia and Pseudomonas aeruginosa acidify cystic fibrosis airway surface liquid by elevating epithelial monocarboxylate transporter 2 dependent lactate-H+ secretion JP Garnett, KK Kalsi, M Sobotta, J Bearham, G Carr, J Powell, M Brodlie, ... Scientific reports 6 (1), 37955, 2016 | 66 | 2016 |
E-cigarette constituents propylene glycol and vegetable glycerin decrease glucose uptake and its metabolism in airway epithelial cells in vitro M Woodall, J Jacob, KK Kalsi, V Schroeder, E Davis, B Kenyon, I Khan, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 319 (6 …, 2020 | 57 | 2020 |
Metformin prevents the effects of Pseudomonas aeruginosa on airway epithelial tight junctions and restricts hyperglycaemia‐induced bacterial growth WRA Patkee, G Carr, EH Baker, DL Baines, JP Garnett Journal of cellular and molecular medicine 20 (4), 758-764, 2016 | 56 | 2016 |
Rationale and design of the Virginia Commonwealth University–Anakinra Remodeling Trial‐3 (VCU‐ART3): A randomized, placebo‐controlled, double‐blinded, multicenter study BW Van Tassell, MJ Lipinski, D Appleton, CS Roberts, MC Kontos, ... Clinical cardiology 41 (8), 1004-1008, 2018 | 50 | 2018 |
Human lung fibroblast-to-myofibroblast transformation is not driven by an LDH5-dependent metabolic shift towards aerobic glycolysis E Schruf, V Schroeder, CA Kuttruff, S Weigle, M Krell, M Benz, ... Respiratory research 20, 1-10, 2019 | 43 | 2019 |
Development of a miniaturized 96-Transwell air–liquid interface human small airway epithelial model T Bluhmki, S Bitzer, JA Gindele, E Schruf, T Kiechle, M Webster, ... Scientific reports 10 (1), 13022, 2020 | 42 | 2020 |
Recapitulating idiopathic pulmonary fibrosis related alveolar epithelial dysfunction in a human iPSC‐derived air‐liquid interface model E Schruf, V Schroeder, HQ Le, T Schönberger, D Raedel, EL Stewart, ... The FASEB Journal 34 (6), 7825-7846, 2020 | 38 | 2020 |
Effect of acute myocardial infarction on the utility of fractional flow reserve for the physiologic assessment of the severity of coronary artery narrowing JC McClish, M Ragosta, ER Powers, KG Barringhaus, LW Gimple, ... The American journal of cardiology 93 (9), 1102-1106, 2004 | 37 | 2004 |
Dapagliflozin‐lowered blood glucose reduces respiratory Pseudomonas aeruginosa infection in diabetic mice A Åstrand, C Wingren, A Benjamin, JS Tregoning, JP Garnett, H Groves, ... British Journal of Pharmacology 174 (9), 836-847, 2017 | 35 | 2017 |
Fructose transport-deficient Staphylococcus aureus reveals important role of epithelial glucose transporters in limiting sugar-driven bacterial growth in airway … JP Garnett, D Braun, AJ McCarthy, MR Farrant, EH Baker, JA Lindsay, ... Cellular and molecular life sciences 71, 4665-4673, 2014 | 34 | 2014 |
Metformin attenuates the effect of Staphylococcus aureus on airway tight junctions by increasing PKCζ‐mediated phosphorylation of occludin KK Kalsi, JP Garnett, W Patkee, A Weekes, ME Dockrell, EH Baker, ... Journal of cellular and molecular medicine 23 (1), 317-327, 2019 | 27 | 2019 |