Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13153* | 2021 |
Mitofusin 2 (Mfn2) links mitochondrial and endoplasmic reticulum function with insulin signaling and is essential for normal glucose homeostasis D Sebastián, MI Hernández-Alvarez, J Segalés, E Sorianello, JP Muñoz, ... Proceedings of the National Academy of Sciences 109 (14), 5523-5528, 2012 | 701 | 2012 |
Mitofusin 2 in POMC neurons connects ER stress with leptin resistance and energy imbalance M Schneeberger, MO Dietrich, D Sebastián, M Imbernón, C Castaño, ... Cell 155 (1), 172-187, 2013 | 507 | 2013 |
Mfn2 modulates the UPR and mitochondrial function via repression of PERK JP Muñoz, S Ivanova, J Sánchez‐Wandelmer, P Martínez‐Cristóbal, ... The EMBO journal 32 (17), 2348-2361, 2013 | 427 | 2013 |
Mfn2 deficiency links age‐related sarcopenia and impaired autophagy to activation of an adaptive mitophagy pathway D Sebastián, E Sorianello, J Segalés, A Irazoki, V Ruiz‐Bonilla, D Sala, ... The EMBO journal 35 (15), 1677-1693, 2016 | 341 | 2016 |
Deficient endoplasmic reticulum-mitochondrial phosphatidylserine transfer causes liver disease MI Hernández-Alvarez, D Sebastián, S Vives, S Ivanova, P Bartoccioni, ... Cell 177 (4), 881-895. e17, 2019 | 287 | 2019 |
Mitochondrial dynamics: coupling mitochondrial fitness with healthy aging D Sebastián, M Palacín, A Zorzano Trends in molecular medicine 23 (3), 201-215, 2017 | 286 | 2017 |
Mitochondrial fusion proteins: dual regulators of morphology and metabolism A Zorzano, M Liesa, D Sebastián, J Segalés, M Palacín Seminars in cell & developmental biology 21 (6), 566-574, 2010 | 245 | 2010 |
Mitochondrial DNA and TLR9 drive muscle inflammation upon Opa1 deficiency A Rodríguez‐Nuevo, A Díaz‐Ramos, E Noguera, F Díaz‐Sáez, X Duran, ... The EMBO journal 37 (10), e96553, 2018 | 180 | 2018 |
Muscle-specific IRS-1 Ser→ Ala transgenic mice are protected from fat-induced insulin resistance in skeletal muscle K Morino, S Neschen, S Bilz, S Sono, D Tsirigotis, RM Reznick, I Moore, ... Diabetes 57 (10), 2644-2651, 2008 | 134 | 2008 |
Novel role of FATP1 in mitochondrial fatty acid oxidation in skeletal muscle cells D Sebastián, M Guitart, C García-Martínez, C Mauvezin, ... Journal of lipid research 50 (9), 1789-1799, 2009 | 130 | 2009 |
Mutant HTT (huntingtin) impairs mitophagy in a cellular model of Huntington disease S Franco-Iborra, A Plaza-Zabala, M Montpeyo, D Sebastian, M Vila, ... Autophagy 17 (3), 672-689, 2021 | 124 | 2021 |
Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes S Bonàs-Guarch, M Guindo-Martínez, I Miguel-Escalada, N Grarup, ... Nature communications 9 (1), 321, 2018 | 123 | 2018 |
Identification of new activators of mitochondrial fusion reveals a link between mitochondrial morphology and pyrimidine metabolism L Miret-Casals, D Sebastian, J Brea, EM Rico-Leo, M Palacin, ... Cell chemical biology 25 (3), 268-278. e4, 2018 | 104 | 2018 |
CPT I overexpression protects L6E9 muscle cells from fatty acid-induced insulin resistance D Sebastián, L Herrero, D Serra, G Asins, FG Hegardt American Journal of Physiology-Endocrinology and Metabolism 292 (3), E677-E686, 2007 | 104 | 2007 |
Alteration of the Malonyl-CoA/Carnitine Palmitoyltransferase I Interaction in the β-Cell Impairs Glucose-Induced Insulin Secretion L Herrero, B Rubi, D Sebastián, D Serra, G Asins, P Maechler, M Prentki, ... Diabetes 54 (2), 462-471, 2005 | 101 | 2005 |
Autophagy exacerbates muscle wasting in cancer cachexia and impairs mitochondrial function F Penna, R Ballarò, P Martinez-Cristobal, D Sala, D Sebastian, ... Journal of molecular biology 431 (15), 2674-2686, 2019 | 86 | 2019 |
Lack of glycogenin causes glycogen accumulation and muscle function impairment G Testoni, J Duran, M García-Rocha, F Vilaplana, AL Serrano, ... Cell metabolism 26 (1), 256-266. e4, 2017 | 84 | 2017 |
Mitofusin 2 as a driver that controls energy metabolism and insulin signaling A Zorzano, MI Hernández-Alvarez, D Sebastian, JP Muñoz Antioxidants & redox signaling 22 (12), 1020-1031, 2015 | 82 | 2015 |
Role of mitochondrial complex IV in age-dependent obesity I Soro-Arnaiz, QOY Li, M Torres-Capelli, F Meléndez-Rodríguez, S Veiga, ... Cell reports 16 (11), 2991-3002, 2016 | 81 | 2016 |