Targeting chelatable iron as a therapeutic modality in Parkinson's disease D Devos, C Moreau, JC Devedjian, J Kluza, M Petrault, C Laloux, ... Antioxidants & redox signaling 21 (2), 195-210, 2014 | 611 | 2014 |
Farnesoid X receptor inhibits glucagon-like peptide-1 production by enteroendocrine L cells MS Trabelsi, M Daoudi, J Prawitt, S Ducastel, V Touche, SI Sayin, ... Nature communications 6 (1), 7629, 2015 | 365 | 2015 |
Mitochondrial proliferation during apoptosis induced by anticancer agents: effects of doxorubicin and mitoxantrone on cancer and cardiac cells J Kluza, P Marchetti, MA Gallego, S Lancel, C Fournier, A Loyens, ... Oncogene 23 (42), 7018-7030, 2004 | 218 | 2004 |
Mitochondrial spare respiratory capacity: mechanisms, regulation, and significance in non‐transformed and cancer cells P Marchetti, Q Fovez, N Germain, R Khamari, J Kluza The FASEB Journal 34 (10), 13106-13124, 2020 | 201 | 2020 |
Cancer cell mitochondria are direct proapoptotic targets for the marine antitumor drug lamellarin D J Kluza, MA Gallego, A Loyens, JC Beauvillain, JMF Sousa-Faro, ... Cancer Research 66 (6), 3177-3187, 2006 | 196 | 2006 |
Inactivation of the HIF-1α/PDK3 signaling axis drives melanoma toward mitochondrial oxidative metabolism and potentiates the therapeutic activity of pro-oxidants J Kluza, P Corazao-Rozas, Y Touil, M Jendoubi, C Maire, P Guerreschi, ... Cancer research 72 (19), 5035-5047, 2012 | 174 | 2012 |
Mitochondrial oxidative stress is the Achille's heel of melanoma cells resistant to Braf-mutant inhibitor P Corazao-Rozas, P Guerreschi, M Jendoubi, F André, A Jonneaux, ... Oncotarget 4 (11), 1986, 2013 | 173 | 2013 |
Ventricular myocyte caspases are directly responsible for endotoxin-induced cardiac dysfunction S Lancel, O Joulin, R Favory, JF Goossens, J Kluza, C Chopin, ... Circulation 111 (20), 2596-2604, 2005 | 162 | 2005 |
Lactate inhibits the pro-inflammatory response and metabolic reprogramming in murine macrophages in a GPR81-independent manner A Errea, D Cayet, P Marchetti, C Tang, J Kluza, S Offermanns, JC Sirard, ... PloS one 11 (11), e0163694, 2016 | 135 | 2016 |
Mitochondrial electron transport is the cellular target of the oncology drug elesclomol RK Blackman, K Cheung-Ong, M Gebbia, DA Proia, S He, J Kepros, ... PloS one 7 (1), e29798, 2012 | 132 | 2012 |
Air pollution-derived PM2. 5 impairs mitochondrial function in healthy and chronic obstructive pulmonary diseased human bronchial epithelial cells B Leclercq, J Kluza, S Antherieu, J Sotty, LY Alleman, E Perdrix, A Loyens, ... Environmental pollution 243, 1434-1449, 2018 | 118 | 2018 |
Inhibition of mitochondrial respiration mediates apoptosis induced by the anti-tumoral alkaloid lamellarin D C Ballot, J Kluza, S Lancel, A Martoriati, SM Hassoun, L Mortier, ... Apoptosis 15, 769-781, 2010 | 114 | 2010 |
Lamellarin D: a novel pro-apoptotic agent from marine origin insensitive to P-glycoprotein-mediated drug efflux M Vanhuyse, J Kluza, C Tardy, G Otero, C Cuevas, C Bailly, A Lansiaux Cancer Letters 221 (2), 165-175, 2005 | 110 | 2005 |
Inhibition of DNA binding of the NF-Y transcription factor by the pyrrolobenzodiazepine-polyamide conjugate GWL-78 M Kotecha, J Kluza, G Wells, CC O'Hare, C Forni, R Mantovani, ... Molecular cancer therapeutics 7 (5), 1319-1328, 2008 | 86 | 2008 |
Lipid metabolism and resistance to anticancer treatment N Germain, M Dhayer, M Boileau, Q Fovez, J Kluza, P Marchetti Biology 9 (12), 474, 2020 | 83 | 2020 |
Glucose metabolism and NRF2 coordinate the antioxidant response in melanoma resistant to MAPK inhibitors R Khamari, A Trinh, PE Gabert, P Corazao-Rozas, S Riveros-Cruz, ... Cell Death & Disease 9 (3), 325, 2018 | 79 | 2018 |
Overcoming chemoresistance of non-small cell lung carcinoma through restoration of an AIF-dependent apoptotic pathway MA Gallego, C Ballot, J Kluza, N Hajji, A Martoriati, L Castera, C Cuevas, ... Oncogene 27 (14), 1981-1992, 2008 | 79 | 2008 |
Apoptotic response of HL-60 human leukemia cells to the antitumor drug TAS-103 J Kluza, A Lansiaux, N Wattez, C Mahieu, N Osheroff, C Bailly Cancer research 60 (15), 4077-4084, 2000 | 77 | 2000 |
Essential role of mitochondria in apoptosis of cancer cells induced by the marine alkaloid Lamellarin D C Ballot, J Kluza, A Martoriati, U Nyman, P Formstecher, B Joseph, ... Molecular cancer therapeutics 8 (12), 3307-3317, 2009 | 74 | 2009 |
Mitochondrial oxidative phosphorylation controls cancer cell's life and death decisions upon exposure to MAPK inhibitors P Corazao-Rozas, P Guerreschi, F André, PE Gabert, S Lancel, ... Oncotarget 7 (26), 39473, 2016 | 70 | 2016 |