GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects DY Oh, S Talukdar, EJ Bae, T Imamura, H Morinaga, WQ Fan, P Li, WJ Lu, ... Cell 142 (5), 687-698, 2010 | 2685 | 2010 |
Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase S Talukdar, DY Oh, G Bandyopadhyay, D Li, J Xu, J McNelis, M Lu, P Li, ... Nature medicine 18 (9), 1407-1412, 2012 | 1009 | 2012 |
Inflammation Is Necessary for Long-Term but Not Short-Term High-Fat Diet–Induced Insulin Resistance YS Lee, P Li, JY Huh, IJ Hwang, M Lu, JI Kim, M Ham, S Talukdar, A Chen, ... Diabetes 60 (10), 2474-2483, 2011 | 632 | 2011 |
Insulin resistance drives hepatic de novo lipogenesis in nonalcoholic fatty liver disease GI Smith, M Shankaran, M Yoshino, GG Schweitzer, M Chondronikola, ... The Journal of clinical investigation 130 (3), 1453-1460, 2020 | 515 | 2020 |
A long-acting FGF21 molecule, PF-05231023, decreases body weight and improves lipid profile in non-human primates and type 2 diabetic subjects S Talukdar, Y Zhou, D Li, M Rossulek, J Dong, V Somayaji, Y Weng, ... Cell metabolism 23 (3), 427-440, 2016 | 498 | 2016 |
Increased macrophage migration into adipose tissue in obese mice DY Oh, H Morinaga, S Talukdar, EJ Bae, JM Olefsky Diabetes 61 (2), 346-354, 2012 | 425 | 2012 |
LTB4 promotes insulin resistance in obese mice by acting on macrophages, hepatocytes and myocytes P Li, DY Oh, G Bandyopadhyay, WS Lagakos, S Talukdar, O Osborn, ... Nature medicine 21 (3), 239-247, 2015 | 333 | 2015 |
FGF21 regulates sweet and alcohol preference S Talukdar, BM Owen, P Song, G Hernandez, Y Zhang, Y Zhou, WT Scott, ... Cell metabolism 23 (2), 344-349, 2016 | 329 | 2016 |
Maintenance of metabolic homeostasis by Sestrin2 and Sestrin3 JH Lee, AV Budanov, S Talukdar, EJ Park, HL Park, HW Park, ... Cell metabolism 16 (3), 311-321, 2012 | 314 | 2012 |
Adipocyte NCoR Knockout Decreases PPARγ Phosphorylation and Enhances PPARγ Activity and Insulin Sensitivity P Li, WQ Fan, J Xu, M Lu, H Yamamoto, J Auwerx, DD Sears, S Talukdar, ... Cell 147 (4), 815-826, 2011 | 303 | 2011 |
Brain PPAR-[gamma] promotes obesity and is required for the insulin-sensitizing effect of thiazolidinediones M Lu, DA Sarruf, S Talukdar, S Sharma, P Li, G Bandyopadhyay, ... Nature medicine 17 (5), 618-622, 2011 | 302 | 2011 |
Targeting GPR120 and other fatty acid-sensing GPCRs ameliorates insulin resistance and inflammatory diseases S Talukdar, JM Olefsky, O Osborn Trends in pharmacological sciences 32 (9), 543-550, 2011 | 292 | 2011 |
FGF21 Lowers Plasma Triglycerides by Accelerating Lipoprotein Catabolism in White and Brown Adipose Tissues LS Christian Schlein, Saswata Talukdar, Markus Heine, Alexander W. Fischer ... Cell Metabolism, 2016 | 263 | 2016 |
NCoR repression of LXRs restricts macrophage biosynthesis of insulin-sensitizing omega 3 fatty acids P Li, NJ Spann, MU Kaikkonen, M Lu, JN Fox, G Bandyopadhyay, ... Cell 155 (1), 200-214, 2013 | 179 | 2013 |
The mechanism mediating the activation of acetyl-coenzyme A carboxylase-α gene transcription by the liver X receptor agonist T0-901317 S Talukdar, FB Hillgartner Journal of lipid research 47 (11), 2451, 2006 | 145 | 2006 |
Once‐weekly administration of a long‐acting fibroblast growth factor 21 analogue modulates lipids, bone turnover markers, blood pressure and body weight differently in obese … AM Kim, VR Somayaji, JQ Dong, TP Rolph, Y Weng, JR Chabot, ... Diabetes, Obesity and Metabolism 19 (12), 1762-1772, 2017 | 143 | 2017 |
Development of a novel long-acting antidiabetic FGF21 mimetic by targeted conjugation to a scaffold antibody J Huang, T Ishino, G Chen, P Rolzin, TF Osothprarop, K Retting, L Li, ... Journal of Pharmacology and Experimental Therapeutics 346 (2), 270-280, 2013 | 134 | 2013 |
Osteopontin is required for the early onset of high fat diet-induced insulin resistance in mice J Chapman, PD Miles, JM Ofrecio, JG Neels, JG Yu, JL Resnik, J Wilkes, ... PloS one 5 (11), e13959, 2010 | 103 | 2010 |
GPR105 ablation prevents inflammation and improves insulin sensitivity in mice with diet-induced obesity J Xu, H Morinaga, D Oh, P Li, A Chen, S Talukdar, E Lazarowski, ... The Journal of Immunology 189 (4), 1992-1999, 2012 | 88 | 2012 |
Pharmacokinetics (PK), pharmacodynamics (PD) and integrated PK/PD modeling of a novel long acting FGF21 clinical candidate PF-05231023 in diet-induced obese and leptin … Y Weng, JR Chabot, B Bernardo, Q Yan, Y Zhu, MB Brenner, C Vage, ... PloS one 10 (3), e0119104, 2015 | 70 | 2015 |