Dose frequency ranging pharmacokinetic study of tenofovir-emtricitabine after directly observed dosing in healthy volunteers to establish adherence benchmarks (HPTN 066) CW Hendrix, A Andrade, NN Bumpus, AD Kashuba, MA Marzinke, ... AIDS research and human retroviruses 32 (1), 32-43, 2016 | 177 | 2016 |
Hyperosmolar sexual lubricant causes epithelial damage in the distal colon: potential implication for HIV transmission EJ Fuchs, LA Lee, MS Torbenson, TL Parsons, RP Bakshi, AM Guidos, ... The Journal of infectious diseases 195 (5), 703-710, 2007 | 174 | 2007 |
Single dose pharmacokinetics of oral tenofovir in plasma, peripheral blood mononuclear cells, colonic tissue, and vaginal tissue NA Louissaint, YJ Cao, PL Skipper, RG Liberman, SR Tannenbaum, ... AIDS research and human retroviruses 29 (11), 1443-1450, 2013 | 163 | 2013 |
The killing of African trypanosomes by ethidium bromide A Roy Chowdhury, R Bakshi, J Wang, G Yildirir, B Liu, V Pappas-Brown, ... PLoS pathogens 6 (12), e1001226, 2010 | 99 | 2010 |
Long-acting injectable atovaquone nanomedicines for malaria prophylaxis RP Bakshi, LM Tatham, AC Savage, AK Tripathi, G Mlambo, MM Ippolito, ... Nature communications 9 (1), 315, 2018 | 92 | 2018 |
Functional and regulatory characteristics of eukaryotic type II DNA topoisomerase RP Bakshi, S Galande, K Muniyappa Critical reviews in biochemistry and molecular biology 36 (1), 1-37, 2001 | 89 | 2001 |
Transgender women on oral HIV pre‐exposure prophylaxis have significantly lower tenofovir and emtricitabine concentrations when also taking oestrogen when compared to cisgender men E Shieh, MA Marzinke, EJ Fuchs, A Hamlin, R Bakshi, W Aung, J Breakey, ... Journal of the International AIDS Society 22 (11), e25405, 2019 | 76 | 2019 |
RNA interference of Trypanosoma brucei topoisomerase IB: both subunits are essential RP Bakshi, TA Shapiro Molecular and biochemical parasitology 136 (2), 249-255, 2004 | 59 | 2004 |
Quantitative imaging and sigmoidoscopy to assess distribution of rectal microbicide surrogates CW Hendrix, EJ Fuchs, KJ Macura, LA Lee, TL Parsons, RP Bakshi, ... Clinical Pharmacology & Therapeutics 83 (1), 97-105, 2008 | 58 | 2008 |
Isoosmolar enemas demonstrate preferential gastrointestinal distribution, safety, and acceptability compared with hyperosmolar and hypoosmolar enemas as a potential delivery … FJ Leyva, RP Bakshi, EJ Fuchs, L Li, BS Caffo, AJ Goldsmith, ... AIDS research and human retroviruses 29 (11), 1487-1495, 2013 | 54 | 2013 |
Comparison of dapivirine vaginal gel and film formulation pharmacokinetics and pharmacodynamics (FAME 02B) JA Robinson, MA Marzinke, RP Bakshi, EJ Fuchs, CL Radebaugh, ... AIDS research and human retroviruses 33 (4), 339-346, 2017 | 48 | 2017 |
Model system to define pharmacokinetic requirements for antimalarial drug efficacy RP Bakshi, E Nenortas, AK Tripathi, DJ Sullivan, TA Shapiro Science translational medicine 5 (205), 205ra135-205ra135, 2013 | 44 | 2013 |
Distribution of cell-free and cell-associated HIV surrogates in the colon after simulated receptive anal intercourse in men who have sex with men NA Louissaint, S Nimmagadda, EJ Fuchs, RP Bakshi, YJ Cao, LA Lee, ... JAIDS Journal of Acquired Immune Deficiency Syndromes 59 (1), 10-17, 2012 | 43 | 2012 |
Phase I/II evaluation of the prophylactic antimalarial activity of pafuramidine in healthy volunteers challenged with Plasmodium falciparum sporozoites MM Nyunt, CW Hendrix, RP Bakshi, N Kumar, TA Shapiro The American journal of tropical medicine and hygiene 80 (4), 528, 2009 | 37 | 2009 |
DNA topoisomerases as targets for antiprotozoal therapy RP Bakshi, TA Shapiro Mini Reviews in Medicinal Chemistry 3 (6), 597-608, 2003 | 36 | 2003 |
Distribution of cell-free and cell-associated HIV surrogates in the female genital tract after simulated vaginal intercourse NA Louissaint, EJ Fuchs, RP Bakshi, S Nimmagadda, Y Du, KJ Macura, ... Journal of Infectious Diseases 205 (5), 725-732, 2012 | 32 | 2012 |
The male genital tract is not a pharmacological sanctuary from efavirenz LB Avery, RP Bakshi, YJ Cao, CW Hendrix Clinical Pharmacology & Therapeutics 90 (1), 151-156, 2011 | 32 | 2011 |
Comparison of the pharmacokinetics and pharmacodynamics of single-dose tenofovir vaginal film and gel formulation (FAME 05) JA Robinson, MA Marzinke, EJ Fuchs, RP Bakshi, HML Spiegel, ... JAIDS Journal of Acquired Immune Deficiency Syndromes 77 (2), 175-182, 2018 | 31 | 2018 |
Developmental and hormonal regulation of type II DNA topoisomerase in rat testis RP Bakshi, S Galande, P Bali, R Dighe, K Muniyappa Journal of molecular endocrinology 26 (3), 193-206, 2001 | 29 | 2001 |
Quantification of the spatial distribution of rectally applied surrogates for microbicide and semen in colon with SPECT and magnetic resonance imaging YJ Cao, BS Caffo, EJ Fuchs, LA Lee, Y Du, L Li, RP Bakshi, K Macura, ... British journal of clinical pharmacology 74 (6), 1013-1022, 2012 | 28 | 2012 |