Hepatic stellate cell-targeted imatinib nanomedicine versus conventional imatinib: a novel strategy with potent efficacy in experimental liver fibrosis NS El-Mezayen, WF El-Hadidy, WM El-Refaie, TI Shalaby, MM Khattab, ... Journal of controlled release 266, 226-237, 2017 | 52 | 2017 |
Oral vitamin-A-coupled valsartan nanomedicine: High hepatic stellate cell receptors accessibility and prolonged enterohepatic residence NS El-Mezayen, WF El-Hadidy, WM El-Refaie, TI Shalaby, MM Khattab, ... Journal of Controlled Release 283, 32-44, 2018 | 37 | 2018 |
Vitamin B12 as a cholinergic system modulator and blood brain barrier integrity restorer in Alzheimer's disease NS El-Mezayen, RA Abd el Moneim, SH El-Rewini European Journal of Pharmaceutical Sciences 174, 106201, 2022 | 18 | 2022 |
Novel mucoadhesive celecoxib-loaded cubosomal sponges: Anticancer potential and regulation of myeloid-derived suppressor cells in oral squamous cell carcinoma AA Mabrouk, NS El-Mezayen, MI Tadros, ON El-Gazayerly, WM El-Refaie European Journal of Pharmaceutics and Biopharmaceutics 182, 62-80, 2023 | 16 | 2023 |
Fucoidan/hyaluronic acid cross-linked zein nanoparticles loaded with fisetin as a novel targeted nanotherapy for oral cancer MA Moustafa, WM El-Refaie, YSR Elnaggar, NS El-Mezayen, AK Awaad, ... International Journal of Biological Macromolecules 241, 124528, 2023 | 12 | 2023 |
Alleviation of liver cirrhosis and associated portal-hypertension by Astragalus species in relation to their UPLC-MS/MS metabolic profiles: a mechanistic study RS Ibrahim, NS El-Mezayen, AA El‐Banna Scientific Reports 12 (1), 11884, 2022 | 9 | 2022 |
Biologically-guided isolation of natural lead antithyroid drug from Medicago sativa L. sprouts and its toxic profile in comparison with propylthiouracil RS Ibrahim, NS El-Mezayen, A Khairy, HH Zaatout, HM Hammoda, ... Journal of Food and Drug Analysis 28 (3), 407, 2020 | 8 | 2020 |
Nicorandil reduces morphine withdrawal symptoms, potentiates morphine antinociception, and ameliorates liver fibrosis in rats AF Bedair, A Wahid, NS El-Mezayen, EA Afify Life Sciences 319, 121522, 2023 | 7 | 2023 |
Novel celecoxib-loaded chitosan-fucoidan nanoparticles as potential immunotherapy for oral squamous cell carcinoma: Mechanistic insights AA Mabrouk, NS El-Mezayen, AK Awaad, MI Tadros, ON El-Gazayerly, ... Journal of Drug Delivery Science and Technology 81, 104228, 2023 | 7 | 2023 |
Reactive astrocytes targeting with oral vitamin A: Efficient neuronal regeneration for Parkinson's disease treatment and reversal of associated liver fibrosis NS El‐Mezayen, MAM Attia, MY Shafik, HG Gowied, HA Abdel‐Aal, ... CNS Neuroscience & Therapeutics 29 (8), 2111-2128, 2023 | 5 | 2023 |
Evaluation of the anticarcinogenic effect of some peroxisome proliferator activated receptor ligands on dimethylbenz (α) anthracene induced mammary tumor in female rats RE Rizk, WF El-Hadidy, MA Zoheir, NS Ibrahim World J. Pharm. Res. 4, 2078-2099, 2015 | 4 | 2015 |
Reversal of fibrosis and portal hypertension by Empagliflozin treatment of CCl4-induced liver fibrosis: Emphasis on gal-1/NRP-1/TGF-β and gal-1/NRP-1/VEGFR2 pathways AA Noah, NS El-Mezayen, SO El-Ganainy, IE Darwish, EA Afify European Journal of Pharmacology 959, 176066, 2023 | 2 | 2023 |
Nicorandil/morphine crosstalk accounts for antinociception and hepatoprotection in hepatic fibrosis in rats: Distinct roles of opioid/cGMP and NO/KATP pathways AF Bedair, A Wahid, NS El-Mezayen, AF El-Yazbi, HA Khalil, NW Hassan, ... Biomedicine & Pharmacotherapy 165, 115068, 2023 | 2 | 2023 |
Unraveling putative antiulcer phytoconstituents against Helicobacter pylori urease and human H+/K+-ATPase from Jacaranda mimosifolia using UPLC-MS/MS coupled to chemometrics … SM Shoukry, A El-Hawiet, NS El-Mezayen, NM Ghazy, RS Ibrahim Microchemical Journal 189, 108550, 2023 | 2 | 2023 |
Valsartan as a prophylactic treatment against breast cancer development and niche activation: What molecular sequels follow chronic AT-1R blockade? AMA Mansour, MM Khattab, AS El-Khatib, AK Awaad, WM El-Refaie, ... Life Sciences 353, 122939, 2024 | | 2024 |
Cross-relationship between COVID-19 infection and anti-obesity products efficacy and incidence of side effects: A cross-sectional study NS El-Mezayen, YR Abelrazik, DM Khalifa, NM Dorbouk, MA Moaaz, ... Plos one 19 (8), e0309323, 2024 | | 2024 |
Metabolomic insights into the therapeutic mechanisms of costus (Saussurea costus (Falc.) Lipsch.) root extract in propylthiouracil-induced hypothyroidism rat model HM Dawood, NM Barghouth, NS El-Mezayen, RS Ibrahim, E Shawky Journal of Ethnopharmacology 324, 117784, 2024 | | 2024 |
Unraveling putative antiulcer phytoconstituents against Helicobacter pylori urease and human H plus/K plus-ATPase from Jacaranda mimosifolia using UPLC-MS/MS coupled to … SM Shoukry, A El-Hawiet, NS El-Mezayen, NM Ghazy, RS Ibrahim MICROCHEMICAL JOURNAL 189, 2023 | | 2023 |
Potential Efficacy and Proposed Mechanisms of Action of Empagliflozin for the Management of Experimentally-Induced Migraine Headache NS El-Mezayen, AA Noah, NM Shawky, YM Elsheikh, ZM Aslan, ... | | |