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PRAS40 and PRR5-like protein are new mTOR interactors that regulate apoptosis K Thedieck, P Polak, ML Kim, KD Molle, A Cohen, P Jenö, C Arrieumerlou, ... PloS one 2 (11), e1217, 2007 | 396 | 2007 |
Tumor-intrinsic PD-L1 signals regulate cell growth, pathogenesis, and autophagy in ovarian cancer and melanoma CA Clark, HB Gupta, G Sareddy, S Pandeswara, S Lao, B Yuan, ... Cancer research 76 (23), 6964-6974, 2016 | 373 | 2016 |
IL4I1 is a metabolic immune checkpoint that activates the AHR and promotes tumor progression A Sadik, LFS Patterson, S Öztürk, SR Mohapatra, V Panitz, PF Secker, ... Cell 182 (5), 1252-1270. e34, 2020 | 327 | 2020 |
Inhibition of mTORC1 by astrin and stress granules prevents apoptosis in cancer cells K Thedieck, B Holzwarth, MT Prentzell, C Boehlke, K Kläsener, S Ruf, ... Cell 154 (4), 859-874, 2013 | 305 | 2013 |
The MprF protein is required for lysinylation of phospholipids in listerial membranes and confers resistance to cationic antimicrobial peptides (CAMPs) on Listeria monocytogenes K Thedieck, T Hain, W Mohamed, BJ Tindall, M Nimtz, T Chakraborty, ... Molecular microbiology 62 (5), 1325-1339, 2006 | 228 | 2006 |
Proteins induced by telomere dysfunction and DNA damage represent biomarkers of human aging and disease H Jiang, E Schiffer, Z Song, J Wang, P Zürbig, K Thedieck, S Moes, ... Proceedings of the National Academy of Sciences 105 (32), 11299-11304, 2008 | 206 | 2008 |
A dynamic network model of mTOR signaling reveals TSC-independent mTORC2 regulation P Dalle Pezze, AG Sonntag, A Thien, MT Prentzell, M Gödel, S Fischer, ... Science signaling 5 (217), ra25-ra25, 2012 | 175 | 2012 |
Bile proteomic profiles differentiate cholangiocarcinoma from primary sclerosing cholangitis and choledocholithiasis TO Lankisch, J Metzger, AA Negm, K Voβkuhl, E Schiffer, J Siwy, ... Hepatology 53 (3), 875-884, 2011 | 172 | 2011 |
A systems study reveals concurrent activation of AMPK and mTOR by amino acids P Dalle Pezze, S Ruf, AG Sonntag, M Langelaar-Makkinje, P Hall, ... Nature communications 7 (1), 13254, 2016 | 164 | 2016 |
Molecular mechanisms of mTOR regulation by stress AM Heberle, MT Prentzell, K Van Eunen, BM Bakker, SN Grellscheid, ... Molecular & cellular oncology 2 (2), e970489, 2015 | 97 | 2015 |
Podocytes maintain high basal levels of autophagy independent of mtor signaling T Bork, W Liang, K Yamahara, P Lee, Z Tian, S Liu, C Schell, K Thedieck, ... Autophagy 16 (11), 1932-1948, 2020 | 82 | 2020 |
G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling MT Prentzell, U Rehbein, MC Sandoval, AS De Meulemeester, ... Cell 184 (3), 655-674. e27, 2021 | 75 | 2021 |
A modelling–experimental approach reveals insulin receptor substrate (IRS)‐dependent regulation of adenosine monosphosphate‐dependent kinase (AMPK) by insulin AG Sonntag, P Dalle Pezze, DP Shanley, K Thedieck The FEBS journal 279 (18), 3314-3328, 2012 | 74 | 2012 |
TSC1 activates TGF-β-Smad2/3 signaling in growth arrest and epithelial-to-mesenchymal transition A Thien, MT Prentzell, B Holzwarth, K Kläsener, I Kuper, C Boehlke, ... Developmental cell 32 (5), 617-630, 2015 | 73 | 2015 |
PLK1 (polo like kinase 1) inhibits MTOR complex 1 and promotes autophagy S Ruf, AM Heberle, M Langelaar-Makkinje, S Gelino, D Wilkinson, ... Autophagy 13 (3), 486-505, 2017 | 71 | 2017 |
Guidelines for the use and interpretation of assays for monitoring autophagy 1 D Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... Autophagy 17 (1), 1-382, 2021 | 69 | 2021 |
Tomatidine, a novel antiviral compound towards dengue virus M Diosa-Toro, B Troost, D van de Pol, AM Heberle, S Urcuqui-Inchima, ... Antiviral Research 161, 90-99, 2019 | 68 | 2019 |
The PI3K and MAPK/p38 pathways control stress granule assembly in a hierarchical manner AM Heberle, PR Navas, M Langelaar-Makkinje, K Kasack, A Sadik, ... Life science alliance 2 (2), 2019 | 66 | 2019 |
Upregulation of tryptophanyl-tRNA synthethase adapts human cancer cells to nutritional stress caused by tryptophan degradation I Adam, DL Dewi, J Mooiweer, A Sadik, SR Mohapatra, B Berdel, M Keil, ... Oncoimmunology 7 (12), e1486353, 2018 | 53 | 2018 |