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Verónica S. Martinez
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Recon 2.2: from reconstruction to model of human metabolism
N Swainston, K Smallbone, H Hefzi, PD Dobson, J Brewer, M Hanscho, ...
Metabolomics 12, 1-7, 2016
3212016
A consensus genome-scale reconstruction of Chinese hamster ovary cell metabolism
H Hefzi, KS Ang, M Hanscho, A Bordbar, D Ruckerbauer, M Lakshmanan, ...
Cell systems 3 (5), 434-443. e8, 2016
2492016
Flux balance analysis of CHO cells before and after a metabolic switch from lactate production to consumption
VS Martínez, S Dietmair, LE Quek, MP Hodson, P Gray, LK Nielsen
Biotechnology and bioengineering 110 (2), 660-666, 2013
1622013
Reducing Recon 2 for steady-state flux analysis of HEK cell culture
LE Quek, S Dietmair, M Hanscho, VS Martínez, N Borth, LK Nielsen
Journal of biotechnology 184, 172-178, 2014
732014
Dynamic metabolic flux analysis using B-splines to study the effects of temperature shift on CHO cell metabolism
VS Martínez, M Buchsteiner, P Gray, LK Nielsen, LE Quek
Metabolic Engineering Communications 2, 46-57, 2015
652015
Attenuating apoptosis in Chinese hamster ovary cells for improved biopharmaceutical production
MN Henry, MA MacDonald, CA Orellana, PP Gray, M Gillard, K Baker, ...
Biotechnology and Bioengineering 117 (4), 1187-1203, 2020
472020
Network thermodynamic curation of human and yeast genome-scale metabolic models
VS Martínez, LE Quek, LK Nielsen
Biophysical journal 107 (2), 493-503, 2014
382014
Viral vectors for the treatment of alcoholism: use of metabolic flux analysis for cell cultivation and vector production
V Martinez, ZP Gerdtzen, BA Andrews, JA Asenjo
Metabolic engineering 12 (2), 129-137, 2010
322010
Toward Synthetic Biology Strategies for Adipic Acid Production: An in Silico Tool for Combined Thermodynamics and Stoichiometric Analysis of Metabolic Networks
NJH Averesch, VS Martínez, LK Nielsen, JO Kromer
ACS synthetic biology 7 (2), 490-509, 2018
312018
Perfusion culture of Chinese Hamster Ovary cells for bioprocessing applications
MA MacDonald, M Nöbel, D Roche Recinos, VS Martínez, BL Schulz, ...
Critical reviews in biotechnology 42 (7), 1099-1115, 2022
302022
Modeling apoptosis resistance in CHO cells with CRISPR‐mediated knockouts of Bak1, Bax, and Bok
MA MacDonald, C Barry, T Groves, VS Martínez, PP Gray, K Baker, ...
Biotechnology and Bioengineering 119 (6), 1380-1391, 2022
202022
NExT: Integration of Thermodynamic Constraints and Metabolomics Data into a Metabolic Network
VS Martínez, LK Nielsen
Metabolic Flux Analysis: Methods and Protocols, 65-78, 2014
142014
Engineering CHO cells galactose metabolism to reduce lactate synthesis
N Jiménez, VS Martínez, ZP Gerdtzen
Biotechnology letters 41, 779-788, 2019
112019
Engineering death resistance in CHO cells for improved perfusion culture
MA MacDonald, M Nöbel, VS Martínez, K Baker, E Shave, PP Gray, ...
MAbs 14 (1), 2083465, 2022
102022
‘Omics driven discoveries of gene targets for apoptosis attenuation in CHO cells
CA Orellana, VS Martínez, MA MacDonald, MN Henry, M Gillard, PP Gray, ...
Biotechnology and Bioengineering 118 (1), 481-490, 2021
92021
The topology of genome-scale metabolic reconstructions unravels independent modules and high network flexibility
LKN Verónica S. Martínez, Pedro A. Saa, Jason Jooste, Kanupriya Tiwari, Lake ...
PLOS Computational Biology 18 (6), e1010203, 2022
62022
Quantification of microbial phenotypes
VS Martínez, JO Krömer
Metabolites 6 (4), 45, 2016
32016
Amino acid degradation pathway inhibitory by‐products trigger apoptosis in CHO cells
VS Martínez, K Rodriguez, T McCubbin, J Tong, S Mahler, E Shave, ...
Biotechnology Journal 19 (2), 2300338, 2024
12024
Harnessing metabolic plasticity in CHO cells for enhanced perfusion cultivation
M Nöbel, C Barry, MA MacDonald, K Baker, E Shave, S Mahler, T Munro, ...
Biotechnology and Bioengineering 121 (4), 1370-1382, 2024
2024
Amino acid degradation pathway inhibitors trigger apoptosis in Chinese Hamster Ovary cells
V Martinez, K Rodriguez, T McCubbin, J Tong, E Shave, S Mahler, ...
2023
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