Mapping the human genetic architecture of COVID-19 Writing group Writing group leaders Pathak Gita A. 6 Andrews Shea J. 7 Kanai ... Nature 600 (7889), 472-477, 2021 | 782 | 2021 |
Hypoxia and acidosis activate cardiac myocyte death through the Bcl-2 family protein BNIP3 LA Kubasiak, OM Hernandez, NH Bishopric, KA Webster Proceedings of the National Academy of Sciences 99 (20), 12825-12830, 2002 | 562 | 2002 |
Molecular regulation of the endothelin-1 gene by hypoxia: contributions of hypoxia-inducible factor-1, activator protein-1, GATA-2, and p300/CBP K Yamashita, DJ Discher, J Hu, NH Bishopric, KA Webster Journal of Biological Chemistry 276 (16), 12645-12653, 2001 | 454 | 2001 |
Muscle-specific expression of the cardiac alpha-actin gene requires MyoD1, CArG-box binding factor, and Sp1. V Sartorelli, KA Webster, L Kedes Genes & development 4 (10), 1811-1822, 1990 | 396 | 1990 |
Hypoxia regulates expression of the endothelin-1 gene through a proximal hypoxia-inducible factor-1 binding site on the antisense strand J Hu, DJ Discher, NH Bishopric, KA Webster Biochemical and biophysical research communications 245 (3), 894-899, 1998 | 376 | 1998 |
Modulation of cytokine-induced cardiac myocyte apoptosis by nitric oxide, Bak, and Bcl-x DJ Ing, J Zang, VJ Dzau, KA Webster, NH Bishopric Circulation research 84 (1), 21-33, 1999 | 357 | 1999 |
Mitochondrial membrane permeabilization and cell death during myocardial infarction: roles of calcium and reactive oxygen species KA Webster Future cardiology 8 (6), 863-884, 2012 | 351 | 2012 |
Molecular mechanisms of apoptosis in the cardiac myocyte NH Bishopric, P Andreka, T Slepak, KA Webster Current opinion in pharmacology 1 (2), 141-150, 2001 | 340 | 2001 |
Sequence analysis of cDNAs for the human and bovine ATP synthase β subunit: mitochondrial DNA genes sustain seventeen times more mutations DC Wallace, J Ye, SN Neckelmann, G Singh, KA Webster, BD Greenberg Current genetics 12, 81-90, 1987 | 339 | 1987 |
Hypoxia-activated apoptosis of cardiac myocytes requires reoxygenation or a pH shift and is independent of p53 NH Bishopric, DJ Discher, S Kaiser, O Hernandez, B Sato, J Zang, ... The Journal of clinical investigation 104 (3), 239-252, 1999 | 316 | 1999 |
Enhanced cardioprotection by human endometrium mesenchymal stem cells driven by exosomal microRNA-21 K Wang, Z Jiang, KA Webster, J Chen, H Hu, Y Zhou, J Zhao, L Wang, ... Stem cells translational medicine 6 (1), 209-222, 2017 | 295 | 2017 |
Induction and nuclear accumulation of fos and jun proto-oncogenes in hypoxic cardiac myocytes KA Webster, DJ Discher, NH Bishopric Journal of Biological Chemistry 268 (22), 16852-16858, 1993 | 295 | 1993 |
Myocardial reparative functions of exosomes from mesenchymal stem cells are enhanced by hypoxia treatment of the cells via transferring microRNA-210 in an nSMase2-dependent way J Zhu, K Lu, N Zhang, Y Zhao, Q Ma, J Shen, Y Lin, P Xiang, Y Tang, X Hu, ... Artificial cells, nanomedicine, and biotechnology 46 (8), 1659-1670, 2018 | 267 | 2018 |
Physical and functional sensitivity of zinc finger transcription factors to redox change X Wu, NH Bishopric, DJ Discher, BJ Murphy, KA Webster Molecular and Cellular Biology 16 (3), 1035-1046, 1996 | 246 | 1996 |
A unique pathway of cardiac myocyte death caused by hypoxia–acidosis RM Graham, DP Frazier, JW Thompson, S Haliko, H Li, BJ Wasserlauf, ... Journal of Experimental Biology 207 (18), 3189-3200, 2004 | 233 | 2004 |
Hypoxia regulates β-enolase and pyruvate kinase-M promoters by modulating Sp1/Sp3 binding to a conserved GC element DJ Discher, NH Bishopric, X Wu, CA Peterson, KA Webster Journal of Biological Chemistry 273 (40), 26087-26093, 1998 | 229 | 1998 |
Hypoxia/reoxygenation stimulates Jun kinase activity through redox signaling in cardiac myocytes KR Laderoute, KA Webster Circulation research 80 (3), 336-344, 1997 | 226 | 1997 |
Activation of metallothionein gene expression by hypoxia involves metal response elements and metal transcription factor-1 BJ Murphy, GK Andrews, D Bittel, DJ Discher, J McCue, CJ Green, ... Cancer research 59 (6), 1315-1322, 1999 | 224 | 1999 |
Evolution of the coordinate regulation of glycolytic enzyme genes by hypoxia KA Webster Journal of Experimental Biology 206 (17), 2911-2922, 2003 | 217 | 2003 |
Activation of c-Jun N-terminal kinase promotes survival of cardiac myocytes after oxidative stress CJ Dougherty, LA Kubasiak, H Prentice, P Andreka, NH Bishopric, ... Biochemical Journal 362 (3), 561-571, 2002 | 210 | 2002 |