Vaccine adjuvants: current state and future trends N Petrovsky, JC Aguilar Immunology and cell biology 82 (5), 488-496, 2004 | 1340 | 2004 |
Vaccine adjuvants revisited JC Aguilar, EG Rodriguez Vaccine 25 (19), 3752-3762, 2007 | 763 | 2007 |
Development of a nasal vaccine for chronic hepatitis B infection that uses the ability of hepatitis B core antigen to stimulate a strong Th1 response against hepatitis B … JC Aguilar, Y Lobaina, V Muzio, D García, E Pentón, E Iglesias, ... Immunology and cell biology 82 (5), 539-546, 2004 | 133 | 2004 |
Treatment of chronic hepatitis B naïve patients with a therapeutic vaccine containing HBs and HBc antigens (a randomized, open and treatment controlled phase III clinical trial) M Al Mahtab, SMF Akbar, JC Aguilar, G Guillen, E Penton, A Tuero, ... PLoS One 13 (8), e0201236, 2018 | 99 | 2018 |
Therapeutic potential of a combined hepatitis B virus surface and core antigen vaccine in patients with chronic hepatitis B M Al-Mahtab, SMF Akbar, JC Aguilar, MH Uddin, MSI Khan, S Rahman Hepatology international 7, 981-989, 2013 | 94 | 2013 |
A comparative study of different presentation strategies for an HIV peptide immunogen LJ Cruz, E Iglesias, JC Aguilar, LJ González, O Reyes, F Albericio, ... Bioconjugate chemistry 15 (1), 112-120, 2004 | 56 | 2004 |
Characterization of the HCV core virus-like particles produced in the methylotrophic yeast Pichia pastoris N Acosta-Rivero, JC Aguilar, A Musacchio, V Falcón, A Vina, ... Biochemical and biophysical research communications 287 (1), 122-125, 2001 | 54 | 2001 |
Immunological characterization of two hepatitis B core antigen variants and their immunoenhancing effect on co-delivered hepatitis B surface antigen Y Lobaina, D Palenzuela, D Pichardo, V Muzio, G Guillen, JC Aguilar Molecular immunology 42 (3), 289-294, 2005 | 53 | 2005 |
Mucosal immunogenicity of the hepatitis B core antigen Y Lobaina, D Garcıa, N Abreu, V Muzio, JC Aguilar Biochemical and biophysical research communications 300 (3), 745-750, 2003 | 46 | 2003 |
Virus-Like Particles as vaccine antigens and adjuvants: application to chronic disease, cancer immunotherapy and infectious disease preventive strategies G Guillén, JC Aguilar, S Dueñas, L Hermida, MG Guzmán, E Penton, ... Procedia in Vaccinology 2 (2), 128-133, 2010 | 38 | 2010 |
In vitro stimulation with HBV therapeutic vaccine candidate Nasvac activates B and T cells from chronic hepatitis B patients and healthy donors Y Lobaina, S Hardtke, H Wedemeyer, JC Aguilar, V Schlaphoff Molecular Immunology 63 (2), 320-327, 2015 | 35 | 2015 |
The effect of the parenteral route of administration on the immune response to simultaneous nasal and parenteral immunizations using a new HBV therapeutic vaccine candidate Y Lobaina, H Trujillo, D García, A Gambe, Y Chacon, A Blanco, JC Aguilar Viral Immunology 23 (5), 521-529, 2010 | 35 | 2010 |
Different immune response of mice immunized with conjugates containing multiple copies of either consensus or mixotope versions of the V3 loop peptide from human … LJ Cruz, E Iglesias, JC Aguilar, A Cabrales, O Reyes, D Andreu Bioconjugate chemistry 15 (5), 1110-1117, 2004 | 27 | 2004 |
HBV genotypic variability in Cuba CL Loureiro, JC Aguilar, J Aguiar, V Muzio, E Penton, D Garcia, G Guillen, ... PloS one 10 (3), e0118959, 2015 | 26 | 2015 |
Coinoculation with hepatitis B surface and core antigen promotes a Th1 immune response to a multiepitopic protein of HIV‐1 E Iglesias, R Thompson, Y Carrazana, Y Lobaina, D García, J Sánchez, ... Immunology and cell biology 84 (2), 174-183, 2006 | 24 | 2006 |
A C-terminal truncated hepatitis C virus core protein variant assembles in vitro into virus-like particles in the absence of structured nucleic acids N Acosta-Rivero, A Rodriguez, A Mussachio, J Poutu, V Falcon, D Torres, ... Biochemical and biophysical research communications 334 (3), 901-906, 2005 | 24 | 2005 |
Recombinant in vitro assembled hepatitis C virus core particles induce strong specific immunity enhanced by formulation with an oil-based adjuvant N Acosta-Rivero, J Poutou, L Álvarez-Lajonchere, I Guerra, Y Aguilera, ... Biological Research 42 (1), 41-56, 2009 | 23 | 2009 |
Anti-HIV-1 and anti-HBV immune responses in mice after parenteral and nasal co-administration of a multiantigenic formulation E Iglesias, D García, Y Carrazana, JC Aguilar, A Sánchez, L Gorobaya, ... Current HIV research 6 (5), 452-460, 2008 | 22 | 2008 |
Broader cross-reactivity after conjugation of V3 based multiple antigen peptides to HBsAg E Iglesias, JC Aguilar, LJ Cruz, O Reyes Molecular immunology 42 (1), 99-104, 2005 | 22 | 2005 |
Sustained antiviral and liver protection by a nasal therapeutic vaccine (NASVAC, containing both HBsAg and HBcAg) in patients with chronic hepatitis B: 2-year follow-up of … SMF Akbar, M Al Mahtab, JC Aguilar, O Yoshida, E Penton, GN Gerardo, ... Pathogens 10 (11), 1440, 2021 | 21 | 2021 |