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Martin Michael Dcona
Martin Michael Dcona
Research Project Advisor
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标题
引用次数
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Photoswitchable anticancer activity via trans–cis isomerization of a combretastatin A-4 analog
JE Sheldon, MM Dcona, CE Lyons, JC Hackett, MCT Hartman
Organic & biomolecular chemistry 14 (1), 40-49, 2016
1012016
CtBP-an emerging oncogene and novel small molecule drug target: Advances in the understanding of its oncogenic action and identification of therapeutic inhibitors
MM Dcona, BL Morris, KC Ellis, SR Grossman
Cancer biology & therapy 18 (6), 379-391, 2017
822017
Near infrared light mediated release of doxorubicin using upconversion nanoparticles
MM Dcona, Q Yu, JA Capobianco, MCT Hartman
Chemical Communications 51 (40), 8477-8479, 2015
612015
Photocaged permeability: a new strategy for controlled drug release
MM Dcona, D Mitra, RW Goehe, DA Gewirtz, DA Lebman, MCT Hartman
Chemical Communications 48 (39), 4755-4757, 2012
512012
A new, highly water-soluble, fluorescent turn-on chemodosimeter for direct measurement of hydrogen sulfide in biological fluids
MCT Hartman, MM Dcona
Analyst 137 (21), 4910-4912, 2012
412012
Light induced drug release from a folic acid-drug conjugate
MM Dcona, JE Sheldon, D Mitra, MCT Hartman
Bioorganic & medicinal chemistry letters 27 (3), 466-469, 2017
252017
Photocontrolled activation of small molecule cancer therapeutics
MM Dcona, K Mitra, MCT Hartman
RSC Medicinal Chemistry 11 (9), 982-1002, 2020
242020
Cryo-EM structure of CtBP2 confirms tetrameric architecture
AM Jecrois, MM Dcona, X Deng, D Bandyopadhyay, SR Grossman, ...
Structure 29 (4), 310-319. e5, 2021
152021
Active-site tryptophan, the target of antineoplastic C-terminal binding protein inhibitors, mediates inhibitor disruption of CtBP oligomerization and transcription coregulatory …
MM Dcona, PK Damle, F Zarate-Perez, BL Morris, Z Nawaz, MJ Dennis, ...
Molecular pharmacology 96 (1), 99-108, 2019
122019
Coordinate transcriptional regulation of ErbB2/3 by C-terminal binding protein 2 signals sensitivity to ErbB2 inhibition in pancreatic adenocarcinoma
KK Chougoni, H Park, PK Damle, T Mason, B Cheng, MM Dcona, ...
Oncogenesis 12 (1), 53, 2023
12023
Applications of ortho-Nitrobenzyl photocage in cancer-biology
MM Dcona, E Iqbal, S Chrysanthou, M Hemberger, R Khoueiry, KP Koh
Journal of Postdoctoral Research 1, 5, 2018
12018
Orthogonal targeting of NAD metabolism and ErbB2/ErbB3 signaling in pancreatic adenocarcinoma
KK Chougoni, N Kim, MM Dcona, DT Dcona, GK Malhotra, SR Grossman
Cancer Research 84 (6_Supplement), 7217-7217, 2024
2024
Combined targeting of NAD biosynthesis and the NAD-dependent transcription factor C-terminal Binding Protein as a promising novel therapy for pancreatic cancer
MM Dcona, KK Chougoni, DT Dcona, JL West, SJ Singh, KC Ellis, ...
Cancer Research Communications 3 (10), 2003-2013, 2023
2023
C-terminal Binding Protein (CtBP): a critical regulator of ErbB2/3 signaling in PDAC.
KK Chougoni, H Park, PK Damle, MM Dcona, B Szomju, MG Dozmorov, ...
CANCER RESEARCH 82 (22), 106-106, 2022
2022
Abstract B073: C-terminal Binding Protein (CtBP): a critical regulator of ErbB2/3 signaling in PDAC
KK Chougoni, H Park, PK Damle, MM Dcona, B Szomju, MG Dozmorov, ...
Cancer Research 82 (22_Supplement), B073-B073, 2022
2022
CryoEM Structure of CtBP2 Confirms Tetrameric Architecture [preprint]
AM Jecrois, MM Dcona, X Deng, D Bandyopadhyay, SR Grossman, ...
2020
Tetrameric Assembly of the Oncogenic C-Terminal Binding Proteins
WE Royer, AG Bellesis, AM Jecrois, BJ Hilbert, MM Dcona, SR Grossman, ...
Biophysical Journal 116 (3), 62a, 2019
2019
Active-site tryptophan, the target of anti-neoplastic CtBP inhibitors, mediates inhibitor disruption of CtBP oligomerization and transcription coregulatory activities
MM Dcona, PK Damle, F Zarate-Perez, BL Morris, Z Nawaz, MJ Dennis, ...
Molecular Pharmacology, 2019
2019
Tryptophan 318/324, the target of C-terminal binding protein (CtBP) inhibitors, plays a critical role in CtBP enzymatic activity, oligomerization and transcriptional coregulation
MM Dcona, BL Morris, PK Damle, Z Nawaz, FZ Perez, MJ Dennis, ...
Cancer Research 77 (13_Supplement), 3204-3204, 2017
2017
C-terminal binding protein (CtBP): An emerging oncogene and small molecule drug target in solid tumors
ET Sumner, S Korwar, BL Morris, MM Dcona, BJ Hilbert, WE Royer, ...
Cancer Research 76 (14_Supplement), 2003-2003, 2016
2016
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