Selective hematopoietic stem cell ablation using CD117-antibody-drug-conjugates enables safe and effective transplantation with immunity preservation A Czechowicz, R Palchaudhuri, A Scheck, YU Hu, J Hoggatt, B Saez, ... Nature communications 10 (1), 617, 2019 | 164 | 2019 |
Vascular niche promotes hematopoietic multipotent progenitor formation from pluripotent stem cells JL Gori, JM Butler, YY Chan, D Chandrasekaran, MG Poulos, M Ginsberg, ... The Journal of clinical investigation 125 (3), 1243-1254, 2015 | 127 | 2015 |
A distinct hematopoietic stem cell population for rapid multilineage engraftment in nonhuman primates S Radtke, JE Adair, MA Giese, YY Chan, ZK Norgaard, M Enstrom, ... Science translational medicine 9 (414), eaan1145, 2017 | 107 | 2017 |
Purification of human CD34+ CD90+ HSCs reduces target cell population and improves lentiviral transduction for gene therapy S Radtke, D Pande, M Cui, AM Perez, YY Chan, M Enstrom, S Schmuck, ... Molecular Therapy Methods & Clinical Development 18, 679-691, 2020 | 36 | 2020 |
MISTRG mice support engraftment and assessment of nonhuman primate hematopoietic stem and progenitor cells S Radtke, YY Chan, TR Sippel, HP Kiem, A Rongvaux Experimental hematology 70, 31-41. e1, 2019 | 23 | 2019 |
Physioxia improves the selectivity of hematopoietic stem cell expansion cultures KJ Igarashi, I Kucinski, YY Chan, TK Tan, HM Khoo, D Kealy, J Bhadury, ... Blood Advances 7 (14), 3366-3377, 2023 | 12 | 2023 |
Selective hematopoietic stem cell ablation using CD117-antibody-drugconjugates enables safe and effective transplantation with immunity preservation. Nat. Commun. 10, 617 A Czechowicz, R Palchaudhuri, A Scheck, Y Hu, J Hoggatt, B Saez, ... | 7 | 2019 |
Non-Genotoxic Restoration of the Hematolymphoid System in Fanconi Anemia YY Chan, PY Ho, L Swartzrock, M Rayburn, R Nofal, S Thongthip, ... Transplantation and Cellular Therapy 29 (3), 164. e1-164. e9, 2023 | 4 | 2023 |
Sort-purification of human CD34+CD90+ cells reduces target cell population and improves lentiviral transduction S Radtke, D Pande, M Cui, AM Perez, YY Chan, M Enstrom, S Schmuck, ... bioRxiv, 850479, 2019 | 4 | 2019 |
Radiation and Busulfan-Free Hematopoietic Stem Cell Transplantation Using Briquilimab (JSP191) Anti-CD117 Antibody-Conditioning, Transient Immunosuppression and TCRαβ+ T-Cell … R Agarwal, A Bertaina, CF Soco, G Saini, N Kunte, L Hiroshima, YY Chan, ... Blood 142, 229, 2023 | 2 | 2023 |
A novel highly conserved hematopoietic stem/progenitor cell population for stem cell transplantation and gene therapy S Radtke, YY Chan, MA Giese, A Rongvaux, J Adair, HP Kiem Blood 130, 3339, 2017 | 1 | 2017 |
Initial Results from Stanford Children’s Fanconi Anemia Clinical Trial Using JSP191 Antibody Conditioning and TCRαβ+ T-Cell/CD19+ B-Cell Depleted Grafts R Agarwal, A Bertaina, R Nofal, G Saini, N Kunte, S Sen, YY Chan, ... 2023 Tandem Meetings| Transplantation & Cellular Therapy Meetings of ASTCT …, 2023 | | 2023 |
Non-Genotoxic Restoration of the Hematolymphoid System in Fanconi Anemia Mice through Antibody-Mediated Hematopoietic Stem Cell Transplantation YY Chan, PY Ho, L Swartzrock, M Rayburn, R Nofal, S Thongthip, ... Blood 140 (Supplement 1), 7342-7344, 2022 | | 2022 |
Hematopoietic and Immunological Assessment in Fanconi Anemia after Ex Vivo Lentiviral FANCA Gene Therapy with RP-L102 R Nofal, YY Chan, S Sen, U Juarez Figueroa, H Willner, M Felber, ... Blood 140 (Supplement 1), 7772-7773, 2022 | | 2022 |
Hematopoiesis post anti-CD117 monoclonal antibody treatment in wild-type and Fanconi anemia settings M Denis, L Swartzrock, H Willner, QR Bubb, E Haslett, YY Chan, A Chen, ... Haematologica, 2020 | | 2020 |
Fully Closed, Large-Scale, and Clinical Grade Cell Sorting of Hematopoietic Stem Cell (HSC)-Enriched CD90+ Cells for Transplantation and Gene Therapy S Radtke, M Cui, AM Perez, YY Chan, S Schmuck, AJ Berger, T Eunson, ... Blood 134, 3246, 2019 | | 2019 |
Fully-Closed System Cell Sorting of CD90 (+) Results in More Efficient Hematopoietic Stem/Progenitor Cell Transduction S Radtke, M Cui, YY Chan, AM Perez, A Berger, T Eunson, HP Kiem MOLECULAR THERAPY 27 (4), 85-85, 2019 | | 2019 |
A Novel Target for Hematopoietic Stem Cell (HSC) Gene Therapy and Editing S Radtke, M Enstrom, YY Chan, AM Perez, MA Giese, JE Adair, HP Kiem MOLECULAR THERAPY 26 (5), 16-17, 2018 | | 2018 |
Early and Stable Engraftment of a Population of Highly-Enriched Long-Term Multi-Potent Hematopoietic Stem Cells JE Adair, S Radtke, ZK Norgaard, KG Haworth, LE Schefter, MA Giese, ... MOLECULAR THERAPY 25 (5), 339-339, 2017 | | 2017 |
Identification and Characterization of a Distinct, Evolutionarily Conserved HSC Phenotype Associated with and Predicting Multi-Lineage Engraftment S Radtke, MA Giese, YY Chan, ZK Norgaard, JE Adair, HP Kiem Blood, The Journal of the American Society of Hematology 128 (22), 1153-1153, 2016 | | 2016 |