Role of PI3K/Akt and MEK/ERK signaling pathways in sulforaphane-and erucin-induced phase II enzymes and MRP2 transcription, G2/M arrest and cell death in Caco-2 cells J Jakubíková, J Sedlák, R Mithen, Y Bao Biochemical pharmacology 69 (11), 1543-1552, 2005 | 213 | 2005 |
Cytosine deaminase expressing human mesenchymal stem cells mediated tumour regression in melanoma bearing mice L Kucerova, M Matuskova, A Pastorakova, S Tyciakova, J Jakubikova, ... The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2008 | 208 | 2008 |
Lenalidomide targets clonogenic side population in multiple myeloma: pathophysiologic and clinical implications J Jakubikova, S Adamia, M Kost-Alimova, S Klippel, D Cervi, JF Daley, ... Blood, The Journal of the American Society of Hematology 117 (17), 4409-4419, 2011 | 180 | 2011 |
Histone deacetylase 3 as a novel therapeutic target in multiple myeloma J Minami, R Suzuki, R Mazitschek, G Gorgun, B Ghosh, D Cirstea, Y Hu, ... Leukemia 28 (3), 680-689, 2014 | 163 | 2014 |
Targeting NAD+ salvage pathway induces autophagy in multiple myeloma cells via mTORC1 and extracellular signal-regulated kinase (ERK1/2) inhibition M Cea, A Cagnetta, M Fulciniti, YT Tai, T Hideshima, D Chauhan, ... Blood, The Journal of the American Society of Hematology 120 (17), 3519-3529, 2012 | 157 | 2012 |
Antimyeloma activity of the orally bioavailable dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 DW McMillin, M Ooi, J Delmore, J Negri, P Hayden, N Mitsiades, ... Cancer research 69 (14), 5835-5842, 2009 | 155 | 2009 |
Canonical and noncanonical Hedgehog pathway in the pathogenesis of multiple myeloma S Blotta, J Jakubikova, T Calimeri, AM Roccaro, N Amodio, AK Azab, ... Blood, The Journal of the American Society of Hematology 120 (25), 5002-5013, 2012 | 153 | 2012 |
Isothiocyanates induce cell cycle arrest, apoptosis and mitochondrial potential depolarization in HL-60 and multidrug-resistant cell lines J Jakubikova, Y Bao, J Sedlák Anticancer Research 25 (5), 3375-3386, 2005 | 147 | 2005 |
Interactions between sulforaphane and apigenin in the induction of UGT1A1 and GSTA1 in CaCo-2 cells V Švehlíková, S Wang, J Jakubíková, G Williamson, R Mithen, Y Bao Carcinogenesis 25 (9), 1629-1637, 2004 | 120 | 2004 |
Garlic-derived organosulfides induce cytotoxicity, apoptosis, cell cycle arrest and oxidative stress in human colon carcinoma cell lines. J Jakubikova, J Sedlak Neoplasma 53 (3), 191-199, 2006 | 103 | 2006 |
Anti-tumor activity and signaling events triggered by the isothiocyanates, sulforaphane and phenethyl isothiocyanate, in multiple myeloma J Jakubikova, D Cervi, M Ooi, K Kim, S Nahar, S Klippel, D Cholujova, ... Haematologica 96 (8), 1170, 2011 | 92 | 2011 |
The interaction of bortezomib with multidrug transporters: implications for therapeutic applications in advanced multiple myeloma and other neoplasias R O’Connor, MG Ooi, J Meiller, J Jakubikova, S Klippel, J Delmore, ... Cancer chemotherapy and pharmacology 71, 1357-1368, 2013 | 90 | 2013 |
Accessory cells of the microenvironment protect multiple myeloma from T-cell cytotoxicity through cell adhesion-mediated immune resistance SJ de Haart, NWCJ van de Donk, MC Minnema, JH Huang, ... Clinical cancer research 19 (20), 5591-5601, 2013 | 77 | 2013 |
Class IIa HDAC inhibition enhances ER stress-mediated cell death in multiple myeloma S Kikuchi, R Suzuki, H Ohguchi, Y Yoshida, D Lu, F Cottini, J Jakubikova, ... Leukemia 29 (9), 1918-1927, 2015 | 74 | 2015 |
Rational combination treatment with histone deacetylase inhibitors and immunomodulatory drugs in multiple myeloma T Hideshima, F Cottini, H Ohguchi, J Jakubikova, G Gorgun, N Mimura, ... Blood cancer journal 5 (5), e312-e312, 2015 | 73 | 2015 |
MGN-3 arabinoxylan rice bran modulates innate immunity in multiple myeloma patients D Cholujova, J Jakubikova, B Czako, M Martisova, L Hunakova, J Duraj, ... Cancer Immunology, Immunotherapy 62, 437-445, 2013 | 73 | 2013 |
Selective and potent Akt inhibition triggers anti-myeloma activities and enhances fatal endoplasmic reticulum stress induced by proteasome inhibition N Mimura, T Hideshima, T Shimomura, R Suzuki, H Ohguchi, O Rizq, ... Cancer research 74 (16), 4458-4469, 2014 | 71 | 2014 |
Comparative study of four fluorescent probes for evaluation of natural killer cell cytotoxicity assays D Cholujová, J Jakubíková, M Kubeš, B Arendacká, M Sapák, R Ihnatko, ... Immunobiology 213 (8), 629-640, 2008 | 71 | 2008 |
A novel 3D mesenchymal stem cell model of the multiple myeloma bone marrow niche: biologic and clinical applications J Jakubikova, D Cholujova, T Hideshima, P Gronesova, A Soltysova, ... Oncotarget 7 (47), 77326, 2016 | 70 | 2016 |
Cytotoxic and DNA‐Damaging Effects of Diterpenoid Quinones from the Roots of Salvia officinalis L. on Colonic and Hepatic Human Cells Cultured in vitro D Slameňová, I Mašterová, J Lábaj, E Horváthová, P Kubala, ... Basic & clinical pharmacology & toxicology 94 (6), 282-290, 2004 | 70 | 2004 |