Beyond cell–cell adhesion: sensational cadherins for hearing and balance A Jaiganesh, Y Narui, R Araya-Secchi, M Sotomayor Cold Spring Harbor perspectives in biology 10 (9), a029280, 2018 | 57 | 2018 |
Critical role of the first transmembrane domain of Cx26 in regulating oligomerization and function O Jara, R Acuña, IE García, J Maripillán, V Figueroa, JC Sáez, ... Molecular biology of the cell 23 (17), 3299-3311, 2012 | 57 | 2012 |
An elastic element in the protocadherin-15 tip link of the inner ear R Araya-Secchi, BL Neel, M Sotomayor Nature communications 7 (1), 13458, 2016 | 55 | 2016 |
Characterization of a novel water pocket inside the human Cx26 hemichannel structure R Araya-Secchi, T Perez-Acle, S Kang, T Huynh, A Bernardin, Y Escalona, ... Biophysical journal 107 (3), 599-612, 2014 | 45 | 2014 |
Structural determinants of protocadherin-15 mechanics and function in hearing and balance perception D Choudhary, Y Narui, BL Neel, LN Wimalasena, CF Klanseck, ... Proceedings of the National Academy of Sciences 117 (40), 24837-24848, 2020 | 40 | 2020 |
Computational modeling study of functional microdomains in cannabinoid receptor type 1 A Gonzalez, LS Duran, R Araya-Secchi, JA Garate, CD Pessoa-Mahana, ... Bioorganic & medicinal chemistry 16 (8), 4378-4389, 2008 | 33 | 2008 |
A mechanically weak extracellular membrane-adjacent domain induces dimerization of protocadherin-15 P De-la-Torre, D Choudhary, R Araya-Secchi, Y Narui, M Sotomayor Biophysical Journal 115 (12), 2368-2385, 2018 | 32 | 2018 |
Multidomain convergence of Argonaute during RISC assembly correlates with the formation of internal water clusters MS Park, R Araya-Secchi, JA Brackbill, HD Phan, AC Kehling, ... Molecular cell 75 (4), 725-740. e6, 2019 | 31 | 2019 |
Dual Inhibitory Pathways of Metallofullerenol Gd@C82(OH)22 on Matrix Metalloproteinase-2: Molecular insight into drug-like nanomedicine S Kang, R Araya-Secchi, D Wang, B Wang, T Huynh, R Zhou Scientific Reports 4 (1), 4775, 2014 | 29 | 2014 |
Order and disorder—An integrative structure of the full-length human growth hormone receptor N Kassem, R Araya-Secchi, K Bugge, A Barclay, H Steinocher, ... Science Advances 7 (27), eabh3805, 2021 | 24 | 2021 |
Functional characterization of the ATPase-like activity displayed by a catalytic amyloid C Castillo-Caceres, E Duran-Meza, E Nova, R Araya-Secchi, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1865 (1), 129729, 2021 | 21 | 2021 |
Molecular dynamics study of the archaeal aquaporin AqpM R Araya-Secchi, JA Garate, DS Holmes, T Perez-Acle BMC genomics 12, 1-13, 2011 | 20 | 2011 |
1-benzoyl-2-(2-nitrophenyl)-1H-benzimidazole derivatives: A novel approach to the development of new HIV-1 reverse transcriptase inhibitors D Vásquez, CF Lagos, J Mella-Raipán, L González, R Ebensperger, ... Journal of the Chilean Chemical Society 52 (4), 1281-1287, 2007 | 15 | 2007 |
Exploring the membrane potential of simple dual-membrane systems as models for gap-junction channels Y Escalona, JA Garate, R Araya-Secchi, T Huynh, R Zhou, T Perez-Acle Biophysical Journal 110 (12), 2678-2688, 2016 | 14 | 2016 |
An eleven amino acid residue deletion expands the substrate specificity of acetyl xylan esterase II (AXE II) from Penicillium purpurogenum M Colombres, JA Garate, CF Lagos, R Araya-Secchi, P Norambuena, ... Journal of computer-aided molecular design 22, 19-28, 2008 | 13 | 2008 |
The intracellular lipid-binding domain of human Na+/H+ exchanger 1 forms a lipid-protein co-structure essential for activity R Hendus-Altenburger, J Vogensen, ES Pedersen, A Luchini, ... Communications Biology 3 (1), 731, 2020 | 11 | 2020 |
Protein Function in Extremely Acidic Conditions: Molecular Simulations of a Predicted Aquaporin and a Potassium Channel in Acidithiobacillus Ferrooxidans F Duarte, R Araya-Secchi, W González, T Perez-Acle, D González-Nilo, ... Advanced Materials Research 71, 211-214, 2009 | 9 | 2009 |
The prolactin receptor scaffolds Janus kinase 2 via co-structure formation with phosphoinositide-4, 5-bisphosphate R Araya-Secchi, K Bugge, P Seiffert, A Petry, GW Haxholm, ... Elife 12, e84645, 2023 | 7 | 2023 |
Collective mechanical responses of cadherin-based adhesive junctions as predicted by simulations BL Neel, CR Nisler, S Walujkar, R Araya-Secchi, M Sotomayor Biophysical Journal 121 (6), 991-1012, 2022 | 6 | 2022 |
Molecular modeling of Trypanosoma cruzi glutamate cysteine ligase and investigation of its interactions with glutathione CF Lagos, R Araya-Secchi, P Thomas, T Pérez-Acle, RA Tapia, CO Salas Journal of molecular modeling 18, 2055-2064, 2012 | 5 | 2012 |