Exploiting CRISPR-Cas nucleases to produce sequence-specific antimicrobials D Bikard, CW Euler, W Jiang, PM Nussenzweig, GW Goldberg, X Duportet, ... Nature biotechnology 32 (11), 1146-1150, 2014 | 1001 | 2014 |
Evolution of autoantibody responses via somatic hypermutation outside of germinal centers J William, C Euler, S Christensen, MJ Shlomchik Science 297 (5589), 2066-2070, 2002 | 614 | 2002 |
Synergism between a Novel Chimeric Lysin and Oxacillin Protects against Infection by Methicillin-Resistant Staphylococcus aureus A Daniel, C Euler, M Collin, P Chahales, KJ Gorelick, VA Fischetti Antimicrobial agents and chemotherapy 54 (4), 1603-1612, 2010 | 305 | 2010 |
Novel phage lysin capable of killing the multidrug-resistant gram-negative bacterium Acinetobacter baumannii in a mouse bacteremia model R Lood, BY Winer, AJ Pelzek, R Diez-Martinez, M Thandar, CW Euler, ... Antimicrobial agents and chemotherapy 59 (4), 1983-1991, 2015 | 267 | 2015 |
Novel bacteriophage lysin with broad lytic activity protects against mixed infection by Streptococcus pyogenes and methicillin-resistant Staphylococcus aureus DB Gilmer, JE Schmitz, CW Euler, VA Fischetti Antimicrobial agents and chemotherapy 57 (6), 2743-2750, 2013 | 233 | 2013 |
A Novel Chimeric Lysin Shows Superiority to Mupirocin for Skin Decolonization of Methicillin-Resistant and -Sensitive Staphylococcus aureus Strains M Pastagia, C Euler, P Chahales, J Fuentes-Duculan, JG Krueger, ... Antimicrobial agents and chemotherapy 55 (2), 738-744, 2011 | 224 | 2011 |
A novel chimeric phage lysin with high in vitro and in vivo bactericidal activity against Streptococcus pneumoniae R Díez-Martínez, HD De Paz, E García-Fernández, N Bustamante, ... Journal of Antimicrobial Chemotherapy 70 (6), 1763-1773, 2015 | 123 | 2015 |
Novel engineered peptides of a phage lysin as effective antimicrobials against multidrug-resistant Acinetobacter baumannii M Thandar, R Lood, BY Winer, DR Deutsch, CW Euler, VA Fischetti Antimicrobial agents and chemotherapy 60 (5), 2671-2679, 2016 | 122 | 2016 |
Short-lived plasmablasts dominate the early spontaneous rheumatoid factor response: differentiation pathways, hypermutating cell types, and affinity maturation outside the … J William, C Euler, MJ Shlomchik The Journal of Immunology 174 (11), 6879-6887, 2005 | 112 | 2005 |
Gram-negative bacterial lysins C Ghose, CW Euler Antibiotics 9 (2), 74, 2020 | 97 | 2020 |
Lysocins: bioengineered antimicrobials that deliver lysins across the outer membrane of Gram-negative bacteria RD Heselpoth, CW Euler, R Schuch, VA Fischetti Antimicrobial Agents and Chemotherapy 63 (6), 10.1128/aac. 00342-19, 2019 | 81 | 2019 |
Isolation of phage lysins that effectively kill Pseudomonas aeruginosa in mouse models of lung and skin infection A Raz, A Serrano, A Hernandez, CW Euler, VA Fischetti Antimicrobial Agents and Chemotherapy 63 (7), 10.1128/aac. 00024-19, 2019 | 80 | 2019 |
Strains of bacterial species induce a greatly varied acute adaptive immune response: The contribution of the accessory genome U Sela, CW Euler, J Correa da Rosa, VA Fischetti PLoS pathogens 14 (1), e1006726, 2018 | 77 | 2018 |
Using a novel lysin to help control Clostridium difficile infections Q Wang, CW Euler, A Delaune, VA Fischetti Antimicrobial Agents and Chemotherapy 59 (12), 7447-7457, 2015 | 64 | 2015 |
A Highly Active and Negatively Charged Streptococcus pyogenes Lysin with a Rare d-Alanyl-l-Alanine Endopeptidase Activity Protects Mice against Streptococcal … R Lood, A Raz, H Molina, CW Euler, VA Fischetti Antimicrobial agents and chemotherapy 58 (6), 3073-3084, 2014 | 64 | 2014 |
Use of a bacteriophage lysin to identify a novel target for antimicrobial development R Schuch, AJ Pelzek, A Raz, CW Euler, PA Ryan, BY Winer, A Farnsworth, ... PloS one 8 (4), e60754, 2013 | 58 | 2013 |
A natural single-guide RNA repurposes Cas9 to autoregulate CRISPR-Cas expression RE Workman, T Pammi, BTK Nguyen, LW Graeff, E Smith, SM Sebald, ... Cell 184 (3), 675-688. e19, 2021 | 56 | 2021 |
B cell tolerance checkpoints that restrict pathways of antigen-driven differentiation J William, C Euler, N Primarolo, MJ Shlomchik The Journal of Immunology 176 (4), 2142-2151, 2006 | 56 | 2006 |
Visualizing the onset and evolution of an autoantibody response in systemic autoimmunity J William, C Euler, E Leadbetter, A Marshak-Rothstein, MJ Shlomchik The Journal of Immunology 174 (11), 6872-6878, 2005 | 46 | 2005 |
The Phage Lysin PlySs2 Decolonizes Streptococcus suis from Murine Intranasal Mucosa DB Gilmer, JE Schmitz, M Thandar, CW Euler, VA Fischetti PLoS One 12 (1), e0169180, 2017 | 41 | 2017 |