Distant metastasis occurs late during the genetic evolution of pancreatic cancer S Yachida, S Jones, I Bozic, T Antal, R Leary, B Fu, M Kamiyama, ... Nature 467 (7319), 1114-1117, 2010 | 2915 | 2010 |
The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers LA Diaz Jr, RT Williams, J Wu, I Kinde, JR Hecht, J Berlin, B Allen, I Bozic, ... Nature 486 (7404), 537-540, 2012 | 1949 | 2012 |
Mutations driving CLL and their evolution in progression and relapse DA Landau, E Tausch, AN Taylor-Weiner, C Stewart, JG Reiter, J Bahlo, ... Nature 526 (7574), 525-530, 2015 | 1153 | 2015 |
Accumulation of driver and passenger mutations during tumor progression I Bozic, T Antal, H Ohtsuki, H Carter, D Kim, S Chen, R Karchin, ... Proceedings of the National Academy of Sciences 107 (43), 18545-18550, 2010 | 947 | 2010 |
Evolutionary dynamics of cancer in response to targeted combination therapy I Bozic, JG Reiter, B Allen, T Antal, K Chatterjee, P Shah, YS Moon, ... elife 2, e00747, 2013 | 696 | 2013 |
A spatial model predicts that dispersal and cell turnover limit intratumour heterogeneity B Waclaw, I Bozic, ME Pittman, RH Hruban, B Vogelstein, MA Nowak Nature 525 (7568), 261-264, 2015 | 527 | 2015 |
Limited heterogeneity of known driver gene mutations among the metastases of individual patients with pancreatic cancer AP Makohon-Moore, M Zhang, JG Reiter, I Bozic, B Allen, D Kundu, ... Nature genetics 49 (3), 358-366, 2017 | 387 | 2017 |
Clonal evolution in patients with chronic lymphocytic leukaemia developing resistance to BTK inhibition JA Burger, DA Landau, A Taylor-Weiner, I Bozic, H Zhang, K Sarosiek, ... Nature communications 7 (1), 11589, 2016 | 382 | 2016 |
The evolutionary landscape of chronic lymphocytic leukemia treated with ibrutinib targeted therapy DA Landau, C Sun, D Rosebrock, SEM Herman, J Fein, M Sivina, ... Nature communications 8 (1), 2185, 2017 | 184 | 2017 |
Dormant tumour cells, their niches and the influence of immunity ET Goddard, I Bozic, SR Riddell, CM Ghajar Nature cell biology 20 (11), 1240-1249, 2018 | 147 | 2018 |
Reconstructing metastatic seeding patterns of human cancers JG Reiter, AP Makohon-Moore, JM Gerold, I Bozic, K Chatterjee, ... Nature communications 8 (1), 14114, 2017 | 142 | 2017 |
Vertical suppression of the EGFR pathway prevents onset of resistance in colorectal cancers S Misale, I Bozic, J Tong, A Peraza-Penton, A Lallo, F Baldi, KH Lin, ... Nature communications 6 (1), 8305, 2015 | 132 | 2015 |
Quantifying clonal and subclonal passenger mutations in cancer evolution I Bozic, JM Gerold, MA Nowak PLoS computational biology 12 (2), e1004731, 2016 | 131 | 2016 |
Timing and heterogeneity of mutations associated with drug resistance in metastatic cancers I Bozic, MA Nowak Proceedings of the National Academy of Sciences 111 (45), 15964-15968, 2014 | 124 | 2014 |
Growth dynamics in naturally progressing chronic lymphocytic leukaemia M Gruber*, I Bozic*, I Leshchiner*, D Livitz*, K Stevenson, L Rassenti, ... Nature, 1, 2019 | 120 | 2019 |
Dynamics of targeted cancer therapy I Bozic, B Allen, MA Nowak Trends in molecular medicine 18 (6), 311-316, 2012 | 95 | 2012 |
Mathematical model of colorectal cancer initiation C Paterson, H Clevers, I Bozic Proceedings of the National Academy of Sciences 117 (34), 20681-20688, 2020 | 58 | 2020 |
Comprehensive analysis of tumour initiation, spatial and temporal progression under multiple lines of treatment I Leshchiner, D Livitz, JF Gainor, D Rosebrock, O Spiro, A Martinez, ... biorxiv, 508127, 2018 | 56 | 2018 |
Zero-divisor graphs of matrices over commutative rings I Božić, Z Petrović Communications in Algebra 37 (4), 1186-1192, 2009 | 54 | 2009 |
Resisting resistance I Bozic, MA Nowak Annual Review of Cancer Biology 1 (1), 203-221, 2017 | 50 | 2017 |