Lost in transition: start-up of glycolysis yields subpopulations of nongrowing cells JH Van Heerden, MT Wortel, FJ Bruggeman, JJ Heijnen, YJM Bollen, ... Science 343 (6174), 1245114, 2014 | 314 | 2014 |
The timescale of phenotypic plasticity and its impact on competition in fluctuating environments M Stomp, MA van Dijk, HMJ van Overzee, MT Wortel, CAM Sigon, M Egas, ... The American Naturalist 172 (5), E169-E185, 2008 | 157 | 2008 |
Metabolic enzyme cost explains variable trade-offs between microbial growth rate and yield MT Wortel, E Noor, M Ferris, FJ Bruggeman, W Liebermeister PLoS computational biology 14 (2), e1006010, 2018 | 94 | 2018 |
Metabolic states with maximal specific rate carry flux through an elementary flux mode MT Wortel, H Peters, J Hulshof, B Teusink, FJ Bruggeman The FEBS Journal 281 (6), 1547-1555, 2014 | 82 | 2014 |
Metabolic shifts: a fitness perspective for microbial cell factories A Goel, MT Wortel, D Molenaar, B Teusink Biotechnology letters 34, 2147-2160, 2012 | 78 | 2012 |
Low affinity uniporter carrier proteins can increase net substrate uptake rate by reducing efflux E Bosdriesz, MT Wortel, JR Haanstra, MJ Wagner, P De La Torre Cortes, ... Scientific reports 8 (1), 1-9, 2018 | 46 | 2018 |
Evolutionary pressures on microbial metabolic strategies in the chemostat MT Wortel, E Bosdriesz, B Teusink, FJ Bruggeman Scientific reports 6 (1), 29503, 2016 | 46 | 2016 |
Towards evolutionary predictions: Current promises and challenges MT Wortel, D Agashe, SF Bailey, C Bank, K Bisschop, T Blankers, ... Evolutionary applications 16 (1), 3-21, 2023 | 32* | 2023 |
Interplay between constraints, objectives, and optimality for genome-scale stoichiometric models TR Maarleveld, MT Wortel, BG Olivier, B Teusink, FJ Bruggeman PLoS computational biology 11 (4), e1004166, 2015 | 32 | 2015 |
Eco-evolutionary Red Queen dynamics regulate biodiversity in a metabolite-driven microbial system JA Bonachela, MT Wortel, NC Stenseth Scientific reports 7 (1), 17655, 2017 | 24 | 2017 |
Synthetic microbial communities (SynComs) of the human gut: design, assembly, and applications PT van Leeuwen, S Brul, J Zhang, MT Wortel FEMS microbiology reviews 47 (2), fuad012, 2023 | 21 | 2023 |
Fatal attraction in glycolysis: how Saccharomyces cerevisiae manages sudden transitions to high glucose JH van Heerden, MT Wortel, FJ Bruggeman, JJ Heijnen, YJ Bollen, ... Microbial Cell 1 (3), 103-106, 2014 | 10 | 2014 |
The influence of oxygen and oxidative stress on de novo acquisition of antibiotic resistance in E. coli and Lactobacillus lactis W Qi, MJ Jonker, L Teichmann, M Wortel, BH Ter Kuile BMC microbiology 23 (1), 279, 2023 | 7 | 2023 |
An integrated model quantitatively describing metabolism, growth and cell cycle in budding yeast P Palumbo, M Vanoni, F Papa, S Busti, M Wortel, B Teusink, L Alberghina Artificial Life and Evolutionary Computation: 12th Italian Workshop, WIVACE …, 2018 | 6 | 2018 |
Evolutionary coexistence in a fluctuating environment by specialization on resource level MT Wortel Journal of Evolutionary Biology 36 (3), 622-631, 2023 | 5 | 2023 |
Continual evolution through coupled fast and slow feedbacks MT Wortel, H Peters, JA Bonachela, NC Stenseth Proceedings of the National Academy of Sciences 117 (8), 4234-4242, 2020 | 4 | 2020 |
The Effect of the Stringent Response and Oxidative Stress Response on Fitness Costs of De Novo Acquisition of Antibiotic Resistance W Qi, MJ Jonker, D Katsavelis, W de Leeuw, M Wortel, BH Ter Kuile International Journal of Molecular Sciences 25 (5), 2582, 2024 | 3 | 2024 |
Population bottleneck has only marginal effect on fitness evolution and its repeatability in dioecious Caenorhabditis elegans K Bisschop, T Blankers, J Mariën, MT Wortel, M Egas, AT Groot, ... Evolution 76 (8), 1896-1904, 2022 | 3 | 2022 |
Whole-cell metabolic control analysis FJ Bruggeman, M Remeijer, M Droste, L Salinas, M Wortel, R Planqué, ... Biosystems 234, 105067, 2023 | 2 | 2023 |
Metabolism in states of maximal enzyme efficiency A Kremling, W Liebermeister, E Noor, MT Wortel Economic Principles in Cell Biology, 2023 | 1 | 2023 |