Guidelines for the use and interpretation of assays for monitoring autophagy DJ Klionsky, FC Abdalla, H Abeliovich, RT Abraham, A Acevedo-Arozena, ... Autophagy 8 (4), 445-544, 2012 | 10787* | 2012 |
Cellular iron uptake, trafficking and metabolism: Key molecules and mechanisms and their roles in disease DJR Lane, AM Merlot, MLH Huang, DH Bae, PJ Jansson, S Sahni, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1853 (5), 1130-1144, 2015 | 387 | 2015 |
Roads to melanoma: Key pathways and emerging players in melanoma progression and oncogenic signaling J Paluncic, Z Kovacevic, PJ Jansson, D Kalinowski, AM Merlot, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (4), 770-784, 2016 | 237 | 2016 |
P-glycoprotein mediates drug resistance via a novel mechanism involving lysosomal sequestration T Yamagishi, S Sahni, DM Sharp, A Arvind, PJ Jansson, DR Richardson Journal of Biological Chemistry 288 (44), 31761-31771, 2013 | 225 | 2013 |
Dinitrosyliron complexes are the most abundant nitric oxide-derived cellular adduct: biological parameters of assembly and disappearance JR Hickok, S Sahni, H Shen, A Arvind, C Antoniou, LWM Fung, ... Free Radical Biology and Medicine 51 (8), 1558-1566, 2011 | 180 | 2011 |
Molecular functions of the iron-regulated metastasis suppressor, NDRG1, and its potential as a molecular target for cancer therapy BA Fang, Ž Kovačević, KC Park, DS Kalinowski, PJ Jansson, DJR Lane, ... Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1845 (1), 1-19, 2014 | 164 | 2014 |
The renaissance of polypharmacology in the development of anti-cancer therapeutics: Inhibition of the “Triad of Death” in cancer by Di-2-pyridylketone thiosemicarbazones PJ Jansson, DS Kalinowski, DJR Lane, Z Kovacevic, NA Seebacher, ... Pharmacological research 100, 255-260, 2015 | 159 | 2015 |
Metastasis suppressor, NDRG1, mediates its activity through signaling pathways and molecular motors J Sun, D Zhang, DH Bae, S Sahni, P Jansson, Y Zheng, Q Zhao, F Yue, ... Carcinogenesis 34 (9), 1943-1954, 2013 | 150 | 2013 |
Redox cycling metals: Pedaling their roles in metabolism and their use in the development of novel therapeutics DS Kalinowski, C Stefani, S Toyokuni, T Ganz, GJ Anderson, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (4), 727-748, 2016 | 145 | 2016 |
Duodenal Cytochrome b (DCYTB) in Iron Metabolism: An Update on Function and Regulation DJR Lane, DH Bae, AM Merlot, S Sahni, DR Richardson Nutrients 7 (4), 2274-2296, 2015 | 143 | 2015 |
Di-2-pyridylketone 4, 4-dimethyl-3-thiosemicarbazone (Dp44mT) overcomes multidrug resistance by a novel mechanism involving the hijacking of lysosomal P-glycoprotein (Pgp) PJ Jansson, T Yamagishi, A Arvind, N Seebacher, E Gutierrez, A Stacy, ... Journal Of Biological Chemistry 290 (15), 9588-9603, 2015 | 136 | 2015 |
Copper and conquer: copper complexes of di-2-pyridylketone thiosemicarbazones as novel anti-cancer therapeutics KC Park, L Fouani, PJ Jansson, D Wooi, S Sahni, DJR Lane, ... Metallomics 8 (9), 874-886, 2016 | 135 | 2016 |
The role of the antioxidant response in mitochondrial dysfunction in degenerative diseases: Cross‐talk between antioxidant defense, autophagy, and apoptosis MLH Huang, S Chiang, DS Kalinowski, DH Bae, S Sahni, DR Richardson Oxidative Medicine and Cellular Longevity 2019 (1), 6392763, 2019 | 132 | 2019 |
The role of NDRG1 in the pathology and potential treatment of human cancers DH Bae, PJ Jansson, ML Huang, Z Kovacevic, D Kalinowski, CS Lee, ... Journal of clinical pathology 66 (11), 911-917, 2013 | 120 | 2013 |
The metastasis suppressor, N-myc downstream-regulated gene 1 (NDRG1), inhibits stress-induced autophagy in cancer cells S Sahni, DH Bae, DJR Lane, Z Kovacevic, DS Kalinowski, PJ Jansson, ... Journal of Biological Chemistry 289 (14), 9692-9709, 2014 | 96 | 2014 |
Adenosine monophosphate–activated kinase and its key role in catabolism: Structure, regulation, biological activity, and pharmacological activation S Krishan, DR Richardson, S Sahni Molecular pharmacology 87 (3), 363-377, 2015 | 90 | 2015 |
The metastasis suppressor, N-MYC downstream-regulated gene-1 (NDRG1), down-regulates the ErbB family of receptors to inhibit downstream oncogenic signaling pathways Z Kovacevic, SV Menezes, S Sahni, DS Kalinowski, DH Bae, DJR Lane, ... Journal of Biological Chemistry 291 (3), 1029-1052, 2016 | 83 | 2016 |
Nitric oxide suppresses tumor cell migration through N-Myc downstream-regulated gene-1 (NDRG1) expression: role of chelatable iron JR Hickok, S Sahni, Y Mikhed, MG Bonini, DD Thomas Journal of Biological Chemistry 286 (48), 41413-41424, 2011 | 81 | 2011 |
Gene of the month: BECN1 S Sahni, AM Merlot, S Krishan, PJ Jansson, DR Richardson Journal of Clinical Pathology 67 (8), 656-660, 2014 | 80 | 2014 |
A novel class of thiosemicarbazones show multi-functional activity for the treatment of Alzheimer's disease D Palanimuthu, R Poon, S Sahni, R Anjum, D Hibbs, HY Lin, ... European journal of medicinal chemistry 139, 612-632, 2017 | 75 | 2017 |