| Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids BS Freedman, CR Brooks, AQ Lam, H Fu, R Morizane, V Agrawal, ... Nature communications 6 (1), 8715, 2015 | 745 | 2015 |
| The molecular basis of vascular lumen formation in the developing mouse aorta B Strilić, T Kučera, J Eglinger, MR Hughes, KM McNagny, S Tsukita, ... Developmental cell 17 (4), 505-515, 2009 | 431 | 2009 |
| Microbiome-driven allergic lung inflammation is ameliorated by short-chain fatty acids A Cait, MR Hughes, F Antignano, J Cait, PA Dimitriu, KR Maas, ... Mucosal immunology 11 (3), 785-795, 2018 | 326 | 2018 |
| Phosphatidylinositol (3, 4, 5) P3 is essential but not sufficient for Protein Kinase B (PKB) activation; Phosphatidylinositol (3, 4) P2 is required for PKB phosphorylation at … MP Scheid, M Huber, JE Damen, M Hughes, V Kang, P Neilsen, ... Journal of Biological Chemistry 277 (11), 9027-9035, 2002 | 227 | 2002 |
| The Src homology 2 (SH2) domain of SH2-containing inositol phosphatase (SHIP) is essential for tyrosine phosphorylation of SHIP, its association with Shc, and its induction of … L Liu, JE Damen, MR Hughes, I Babic, FR Jirik, G Krystal Journal of Biological Chemistry 272 (14), 8983-8988, 1997 | 174 | 1997 |
| Protein kinase C-δ is a negative regulator of antigen-induced mast cell degranulation M Leitges, K Gimborn, W Elis, J Kalesnikoff, MR Hughes, G Krystal, ... Molecular and cellular biology 22 (12), 3970-3980, 2002 | 163 | 2002 |
| SHIP negatively regulates IgE+ antigen-induced IL-6 production in mast cells by inhibiting NF-κB activity J Kalesnikoff, N Baur, M Leitges, MR Hughes, JE Damen, M Huber, ... The Journal of Immunology 168 (9), 4737-4746, 2002 | 163 | 2002 |
| Gene-edited human kidney organoids reveal mechanisms of disease in podocyte development YK Kim, I Refaeli, CR Brooks, P Jing, RE Gulieva, MR Hughes, NM Cruz, ... Stem cells 35 (12), 2366-2378, 2017 | 143 | 2017 |
| The role of SHIP in cytokine-induced signaling VLAMM Huber, G Krystal Reviews of Physiology, Biochemistry and Pharmacology 149, 87-103, 2004 | 140* | 2004 |
| DMSO represses inflammatory cytokine production from human blood cells and reduces autoimmune arthritis I Elisia, H Nakamura, V Lam, E Hofs, R Cederberg, J Cait, MR Hughes, ... PloS one 11 (3), e0152538, 2016 | 123 | 2016 |
| Butyrate shapes immune cell fate and function in allergic asthma W Yip, MR Hughes, Y Li, A Cait, M Hirst, WW Mohn, KM McNagny Frontiers in Immunology 12, 628453, 2021 | 107 | 2021 |
| Methyltransferase G9A regulates T cell differentiation during murine intestinal inflammation F Antignano, K Burrows, MR Hughes, JM Han, KJ Kron, NM Penrod, ... The Journal of clinical investigation 124 (5), 1945-1955, 2014 | 106 | 2014 |
| SETD7 controls intestinal regeneration and tumorigenesis by regulating Wnt/β-catenin and Hippo/YAP signaling MJ Oudhoff, MJS Braam, SA Freeman, D Wong, DG Rattray, J Wang, ... Developmental cell 37 (1), 47-57, 2016 | 105 | 2016 |
| The role of SHIP1 in macrophage programming and activation MJ Rauh, LM Sly, J Kalesnikoff, MR Hughes, LP Cao, V Lam, G Krystal Biochemical Society Transactions 32 (5), 785-788, 2004 | 105 | 2004 |
| SHIP's C-terminus is essential for its hydrolysis of PIP3 and inhibition of mast cell degranulation JE Damen, MD Ware, J Kalesnikoff, MR Hughes, G Krystal Blood, The Journal of the American Society of Hematology 97 (5), 1343-1351, 2001 | 99 | 2001 |
| SIGIRR, a negative regulator of TLR/IL-1R signalling promotes Microbiota dependent resistance to colonization by enteric bacterial pathogens HP Sham, EYS Yu, MF Gulen, G Bhinder, M Stahl, JM Chan, L Brewster, ... PLoS pathogens 9 (8), e1003539, 2013 | 95 | 2013 |
| The orphan nuclear receptor RORα and group 3 innate lymphoid cells drive fibrosis in a mouse model of Crohn’s disease BC Lo, MJ Gold, MR Hughes, F Antignano, Y Valdez, C Zaph, KW Harder, ... Science immunology 1 (3), eaaf8864-eaaf8864, 2016 | 84 | 2016 |
| Role of Src homology 2-containing-inositol 5′-phosphatase (SHIP) in mast cells and macrophages MJ Rauh, J Kalesnikoff, M Hughes, L Sly, V Lam, G Krystal Biochemical Society Transactions 31 (1), 286-291, 2003 | 83 | 2003 |
| Podocalyxin enhances breast tumor growth and metastasis and is a target for monoclonal antibody therapy KA Snyder, MR Hughes, B Hedberg, J Brandon, DC Hernaez, P Bergqvist, ... Breast cancer research 17, 1-14, 2015 | 77 | 2015 |
| SHIPs ahoy G Krystal, JE Damen, CD Helgason, M Huber, MR Hughes, J Kalesnikoff, ... The international journal of biochemistry & cell biology 31 (10), 1007-1010, 1999 | 77 | 1999 |
Kelly McNagnyU of British Columbia在 brc.ubc.ca 的电子邮件经过验证
