| Receptor tyrosine kinases activate canonical WNT/β-catenin signaling via MAP kinase/LRP6 pathway and direct β-catenin phosphorylation P Krejci, A Aklian, M Kaucka, E Sevcikova, J Prochazkova, JK Masek, ... PloS one 7 (4), e35826, 2012 | 181 | 2012 |
| Fibroblast growth factor and canonical WNT/β-catenin signaling cooperate in suppression of chondrocyte differentiation in experimental models of FGFR signaling in cartilage M Buchtova, V Oralova, A Aklian, J Masek, I Vesela, Z Ouyang, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1852 (5), 839-850, 2015 | 76 | 2015 |
| Multikinase activity of fibroblast growth factor receptor (FGFR) inhibitors SU5402, PD173074, AZD1480, AZD4547 and BGJ398 compromises the use of small chemicals targeting FGFR … I Gudernova, I Vesela, L Balek, M Buchtova, H Dosedelova, M Kunova, ... Human molecular genetics 25 (1), 9-23, 2016 | 70 | 2016 |
| Computer‐assisted engineering of hyperstable fibroblast growth factor 2 P Dvorak, D Bednar, P Vanacek, L Balek, L Eiselleova, V Stepankova, ... Biotechnology and bioengineering 115 (4), 850-862, 2018 | 61 | 2018 |
| An inactivating mutation in intestinal cell kinase, ICK, impairs hedgehog signalling and causes short rib-polydactyly syndrome S Paige Taylor, M Kunova Bosakova, M Varecha, L Balek, T Barta, ... Human molecular genetics 25 (18), 3998-4011, 2016 | 54 | 2016 |
| A novel variant of FGFR3 causes proportionate short stature SG Kant, I Cervenkova, L Balek, L Trantirek, GWE Santen, MC De Vries, ... European Journal of Endocrinology 172 (6), 763-770, 2015 | 47 | 2015 |
| Fibroblast growth factor receptor influences primary cilium length through an interaction with intestinal cell kinase M Kunova Bosakova, A Nita, T Gregor, M Varecha, I Gudernova, B Fafilek, ... Proceedings of the National Academy of Sciences 116 (10), 4316-4325, 2019 | 37 | 2019 |
| Decrease in abundance of apurinic/apyrimidinic endonuclease causes failure of base excision repair in culture-adapted human embryonic stem cells M Krutá, L Bálek, R Hejnová, Z Dobšáková, L Eiselleová, K Matulka, ... Stem Cells 31 (4), 693-702, 2013 | 34 | 2013 |
| Nanodiamonds as “artificial proteins”: Regulation of a cell signalling system using low nanomolar solutions of inorganic nanocrystals L Balek, M Buchtova, MK Bosakova, M Varecha, S Foldynova-Trantirkova, ... Biomaterials 176, 106-121, 2018 | 30 | 2018 |
| ARQ 087 inhibits FGFR signaling and rescues aberrant cell proliferation and differentiation in experimental models of craniosynostoses and chondrodysplasias caused by … L Balek, I Gudernova, I Vesela, M Hampl, V Oralova, MK Bosakova, ... Bone 105, 57-66, 2017 | 26 | 2017 |
| Mutations in GRK2 cause Jeune syndrome by impairing Hedgehog and canonical Wnt signaling M Bosakova, SP Abraham, A Nita, E Hruba, M Buchtova, SP Taylor, ... EMBO Molecular Medicine 12 (11), e11739, 2020 | 21 | 2020 |
| Statins do not inhibit the FGFR signaling in chondrocytes B Fafílek, M Hampl, N Ricankova, I Vesela, L Bálek, MK Bosakova, ... Osteoarthritis and Cartilage 25 (9), 1522-1530, 2017 | 19 | 2017 |
| The inositol phosphatase SHIP2 enables sustained ERK activation downstream of FGF receptors by recruiting Src kinases B Fafilek, L Balek, MK Bosakova, M Varecha, A Nita, T Gregor, ... Science signaling 11 (548), eaap8608, 2018 | 18 | 2018 |
| Proteomic analyses of signalling complexes associated with receptor tyrosine kinase identify novel members of fibroblast growth factor receptor 3 interactome L Balek, P Nemec, P Konik, MK Bosakova, M Varecha, I Gudernova, ... Cellular Signalling 42, 144-154, 2018 | 16 | 2018 |
| One reporter for in-cell activity profiling of majority of protein kinase oncogenes I Gudernova, S Foldynova-Trantirkova, BE Ghannamova, B Fafilek, ... Elife 6, e21536, 2017 | 16 | 2017 |
| Inhibitor repurposing reveals ALK, LTK, FGFR, RET and TRK kinases as the targets of AZD1480 I Gudernova, L Balek, M Varecha, JF Kucerova, MK Bosakova, B Fafilek, ... Oncotarget 8 (65), 109319, 2017 | 11 | 2017 |
| Effect of FGFR inhibitors on chicken limb development D Horakova, P Cela, P Krejci, L Balek, S Moravcová Balková, E Matalova, ... Development, growth & differentiation 56 (8), 555-572, 2014 | 11 | 2014 |
| Automated cell segmentation in phase-contrast images based on classification and region growing R Stoklasa, L Bálek, P Krejčí, P Matula 2015 IEEE 12th International Symposium on Biomedical Imaging (ISBI), 1447-1451, 2015 | 6 | 2015 |
| Thermostable FGF2 polypeptide, use thereof P Dvorak, P Krejci, L BALEK, L EISELLEOVA, Z KONECNA, P DVORAK, ... | 1 | 2017 |
| Nanodiamonds as artificial proteins for regulation of a cell signalling system P Cigler, L Balek, J Havlik, P Krejci, L Trantirek, S Trantirkova US Patent 11,744,855, 2023 | | 2023 |
