Highly efficient DSB-free base editing for streptomycetes with CRISPR-BEST Y Tong, CM Whitford, HL Robertsen, K Blin, TS Jørgensen, AK Klitgaard, ... Proceedings of the National Academy of Sciences 116 (41), 20366-20375, 2019 | 161 | 2019 |
Targeted genome editing in the rare actinomycete Actinoplanes sp. SE50/110 by using the CRISPR/Cas9 system T Wolf, T Gren, E Thieme, D Wibberg, T Zemke, A Pühler, J Kalinowski Journal of biotechnology 231, 122-128, 2016 | 53 | 2016 |
Heterologous AdpA transcription factors enhance landomycin production in Streptomyces cyanogenus S136 under a broad range of growth conditions O Yushchuk, I Ostash, I Vlasiuk, T Gren, A Luzhetskyy, J Kalinowski, ... Applied microbiology and biotechnology 102, 8419-8428, 2018 | 23 | 2018 |
Genetic engineering in Actinoplanes sp. SE50/110− development of an intergeneric conjugation system for the introduction of actinophage-based integrative vectors T Gren, V Ortseifen, D Wibberg, S Schneiker-Bekel, H Bednarz, ... Journal of biotechnology 232, 79-88, 2016 | 22 | 2016 |
The MalR type regulator AcrC is a transcriptional repressor of acarbose biosynthetic genes in Actinoplanes sp. SE50/110 T Wolf, J Droste, T Gren, V Ortseifen, S Schneiker-Bekel, T Zemke, ... BMC genomics 18, 1-14, 2017 | 17 | 2017 |
Distribution of Epsilon-Polylysine Synthetases in Coryneform Bacteria Isolated from Cheese and Human Skin X Jiang, Y Radko, T Gren, E Palazzotto, TS Jørgensen, T Cheng, M Xian, ... Applied and environmental microbiology, 2021 | 16 | 2021 |
Characterization and engineering of Streptomyces griseofuscus DSM 40191 as a potential host for heterologous expression of biosynthetic gene clusters T Gren, CM Whitford, OS Mohite, TS Jørgensen, EE Kontou, JB Nielsen, ... Scientific Reports 11 (1), 18301, 2021 | 14 | 2021 |
Cultivable actinomycetes from rhizosphere of birch (Betula pendula) growing on a coal mine dump in Silets, Ukraine B Ostash, T Gren, Y Hrubskyy, S Tistechok, S Beshley, V Baranov, ... Journal of basic microbiology 54 (8), 851-857, 2014 | 14 | 2014 |
Activation and Identification of a Griseusin Cluster in Streptomyces sp. CA-256286 by Employing Transcriptional Regulators and Multi-Omics Methods C Beck, T Gren, FJ Ortiz-López, TS Jørgensen, D Carretero-Molina, ... Molecules 26 (21), 6580, 2021 | 12 | 2021 |
Discovery and Characterization of Epemicins A and B, New 30-Membered Macrolides from Kutzneria sp. CA-103260 EE Kontou, T Gren, FJ Ortiz-López, E Thomsen, D Oves-Costales, C Díaz, ... ACS chemical biology 16 (8), 1456-1468, 2021 | 11 | 2021 |
Role of the snorA gene in nogalamycin biosynthesis by strain Streptomyces nogalater Lv65 DO Klymyshin, TP Gren’, VO Fedorenko Microbiology 80, 496-501, 2011 | 9 | 2011 |
High-Quality Sequencing, Assembly, and Annotation of the Streptomyces griseofuscus DSM 40191 Genome T Gren, TS Jørgensen, CM Whitford, T Weber Microbiology Resource Announcements 9 (47), 2020 | 8 | 2020 |
Discovery of gargantulides B and C, new 52-membered macrolactones from Amycolatopsis sp. Complete absolute stereochemistry of the gargantulide family D Carretero-Molina, FJ Ortiz-López, T Gren, D Oves-Costales, J Martín, ... Organic Chemistry Frontiers 9 (2), 462-470, 2022 | 7 | 2022 |
Construction of Streptomyces nogalater Lv65 strains with enhanced nogalamicin biosynthesis using regulatory genes DA Klimishin, MV Rabyk, TP Gren’, OY Nimets’, MA Gonchar, ... Applied biochemistry and microbiology 47, 594-598, 2011 | 7 | 2011 |
Systems analysis of highly multiplexed CRISPR-base editing in streptomycetes CM Whitford, T Gren, E Palazzotto, SY Lee, Y Tong, T Weber ACS Synthetic Biology 12 (8), 2353-2366, 2023 | 5 | 2023 |
Identification of the Biosynthetic Gene Cluster for Pyracrimycin A, an Antibiotic Produced by Streptomyces sp. JB Nielsen, T Gren, OS Mohite, TS Jørgensen, AK Klitgaard, ... ACS chemical biology 17 (9), 2411-2417, 2022 | 5 | 2022 |
Influence of transition metals on Streptomyces coelicolor and S. sioyaensis and generation of chromate-reducing mutants T Gren, B Ostash, Y Hrubskyy, S Tistechok, V Fedorenko Folia microbiologica 59, 147-153, 2014 | 5 | 2014 |
Biosynthesis of the Azoxy Compound Azodyrecin from Streptomyces mirabilis P8-A2 M Maleckis, M Wibowo, T Gren, SA Jarmusch, EB Sterndorff, T Booth, ... ACS chemical biology 19 (3), 641-653, 2024 | 4 | 2024 |
Identification and heterologous expression of the globomycin biosynthetic gene cluster D Oves-Costales, T Gren, EB Sterndorff, J Martín, FJ Ortiz-López, ... Synthetic and Systems Biotechnology 8 (2), 206-212, 2023 | 4 | 2023 |
CASCADE-Cas3 Enables Highly Efficient Genome Engineering in Streptomyces Species CM Whitford, P Gockel, D Faurdal, T Gren, R Sigrist, T Weber BioRxiv, 2023.05. 09.539971, 2023 | 4 | 2023 |