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Bernhard C. Lechtenberg
Bernhard C. Lechtenberg
在 wehi.edu.au 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Mechanism and inhibition of the papain‐like protease, PLpro, of SARS‐CoV‐2
T Klemm, G Ebert, DJ Calleja, CC Allison, LW Richardson, JP Bernardini, ...
The EMBO journal 39 (18), e106275, 2020
4012020
Structure of a HOIP/E2~ ubiquitin complex reveals RBR E3 ligase mechanism and regulation
BC Lechtenberg, A Rajput, R Sanishvili, MK Dobaczewska, CF Ware, ...
Nature 529 (7587), 546-550, 2016
1842016
Structural mechanisms in NLR inflammasome signaling
BC Lechtenberg, PD Mace, SJ Riedl
Current opinion in structural biology 29, 17-25, 2014
1282014
NMR resonance assignments of thrombin reveal the conformational and dynamic effects of ligation
BC Lechtenberg, DJD Johnson, SMV Freund, JA Huntington
Proceedings of the National Academy of Sciences 107 (32), 14087-14092, 2010
1162010
Crystal structure of the prothrombinase complex from the venom of Pseudonaja textilis
BC Lechtenberg, TA Murray-Rust, DJD Johnson, TE Adams, ...
Blood, The Journal of the American Society of Hematology 122 (16), 2777-2783, 2013
862013
An ensemble view of thrombin allostery
BC Lechtenberg, SMV Freund, JA Huntington
Biological chemistry 393 (9), 889-898, 2012
752012
GpIbα interacts exclusively with exosite II of thrombin
BC Lechtenberg, SMV Freund, JA Huntington
Journal of molecular biology 426 (4), 881-893, 2014
502014
Chain reactions: molecular mechanisms of RBR ubiquitin ligases
TR Cotton, BC Lechtenberg
Biochemical Society Transactions 48 (4), 1737-1750, 2020
492020
Development and structural analysis of a nanomolar cyclic peptide antagonist for the EphA4 receptor
I Lamberto, BC Lechtenberg, EJ Olson, PD Mace, PE Dawson, SJ Riedl, ...
ACS chemical biology 9 (12), 2787-2795, 2014
462014
The malignant brain tumor repeats of human SCML2 bind to peptides containing monomethylated lysine
CM Santiveri, BC Lechtenberg, MD Allen, A Sathyamurthy, AM Jaulent, ...
Journal of molecular biology 382 (5), 1107-1112, 2008
402008
Engineering nanomolar peptide ligands that differentially modulate EphA2 receptor signaling
M Gomez-Soler, MP Gehring, BC Lechtenberg, E Zapata-Mercado, ...
Journal of Biological Chemistry 294 (22), 8791-8805, 2019
352019
Structure-guided strategy for the development of potent bivalent ERK inhibitors
BC Lechtenberg, PD Mace, EH Sessions, R Williamson, R Stalder, ...
ACS Medicinal Chemistry Letters 8 (7), 726-731, 2017
332017
The elastase-PK101 structure: mechanism of an ultrasensitive activity-based probe revealed
BC Lechtenberg, P Kasperkiewicz, H Robinson, M Drag, SJ Riedl
ACS Chemical Biology 10 (4), 945-951, 2015
312015
Structure of human Vitronectin C-terminal domain and interaction with Yersinia pestis outer membrane protein Ail
K Shin, BC Lechtenberg, LM Fujimoto, Y Yao, SS Bartra, GV Plano, ...
Science advances 5 (9), eaax5068, 2019
252019
The unifying catalytic mechanism of the RING-between-RING E3 ubiquitin ligase family
XS Wang, TR Cotton, SJ Trevelyan, LW Richardson, WT Lee, J Silke, ...
Nature Communications 14 (1), 168, 2023
212023
Structural basis of K63-ubiquitin chain formation by the Gordon-Holmes syndrome RBR E3 ubiquitin ligase RNF216
TR Cotton, SA Cobbold, JP Bernardini, LW Richardson, XS Wang, ...
Molecular cell 82 (3), 598-615. e8, 2022
202022
Modifications of a nanomolar cyclic peptide antagonist for the EphA4 receptor to achieve high plasma stability
EJ Olson, BC Lechtenberg, C Zhao, ER de la Torre, I Lamberto, SJ Riedl, ...
ACS medicinal chemistry letters 7 (9), 841-846, 2016
192016
Insights into drug Repurposing, as well as specificity and compound properties of piperidine-based SARS-CoV-2 PLpro inhibitors
DJ Calleja, N Kuchel, BGC Lu, RW Birkinshaw, T Klemm, M Doerflinger, ...
Frontiers in Chemistry 10, 861209, 2022
182022
Regulation of the EphA2 receptor intracellular region by phosphomimetic negative charges in the kinase-SAM linker
BC Lechtenberg, MP Gehring, TP Light, CR Horne, MW Matsumoto, ...
Nature communications 12 (1), 7047, 2021
182021
Design and characterization of a heterobifunctional degrader of KEAP1
H Chen, NH Nguyen, CM Magtoto, SA Cobbold, GM Bidgood, ...
Redox Biology 59, 102552, 2023
162023
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