Whole-exome sequencing in adult ETP-ALL reveals a high rate of DNMT3A mutations M Neumann, S Heesch, C Schlee, S Schwartz, N Gökbuget, D Hoelzer, ... Blood, The Journal of the American Society of Hematology 121 (23), 4749-4752, 2013 | 312 | 2013 |
Mutational spectrum of adult T-ALL M Neumann, S Vosberg, C Schlee, S Heesch, S Schwartz, N Gökbuget, ... Oncotarget 6 (5), 2754, 2015 | 127 | 2015 |
Molecular alterations in bone marrow mesenchymal stromal cells derived from acute myeloid leukemia patients EK Von der Heide, M Neumann, S Vosberg, AR James, MP Schroeder, ... Leukemia 31 (5), 1069-1078, 2017 | 120 | 2017 |
Isolated trisomy 13 defines a homogeneous AML subgroup with high frequency of mutations in spliceosome genes and poor prognosis T Herold, KH Metzeler, S Vosberg, L Hartmann, C Röllig, F Stölzel, ... Blood, The Journal of the American Society of Hematology 124 (8), 1304-1311, 2014 | 119 | 2014 |
In-depth mutational analyses of colorectal neuroendocrine carcinomas with adenoma or adenocarcinoma components C Woischke, CW Schaaf, HM Yang, M Vieth, L Veits, H Geddert, B Märkl, ... Modern Pathology 30 (1), 95-103, 2017 | 108 | 2017 |
Clonal evolution of acute myeloid leukemia from diagnosis to relapse S Vosberg, PA Greif Genes, chromosomes and cancer 58 (12), 839-849, 2019 | 105 | 2019 |
Evolution of cytogenetically normal acute myeloid leukemia during therapy and relapse: an exome sequencing study of 50 patients PA Greif, L Hartmann, S Vosberg, SM Stief, R Mattes, I Hellmann, ... Clinical cancer research 24 (7), 1716-1726, 2018 | 87 | 2018 |
Loss of KDM6A confers drug resistance in acute myeloid leukemia SM Stief, AL Hanneforth, S Weser, R Mattes, M Carlet, WH Liu, ... Leukemia 34 (1), 50-62, 2020 | 83 | 2020 |
The clinical mutatome of core binding factor leukemia S Opatz, SA Bamopoulos, KH Metzeler, T Herold, B Ksienzyk, K Bräundl, ... Leukemia 34 (6), 1553-1562, 2020 | 70 | 2020 |
Acute myeloid leukemia in the elderly is characterized by a distinct genetic and epigenetic landscape P Silva, M Neumann, MP Schroeder, S Vosberg, C Schlee, K Isaakidis, ... Leukemia 31 (7), 1640-1644, 2017 | 69 | 2017 |
Exome sequencing identifies recurring FLT3 N676K mutations in core-binding factor leukemia S Opatz, H Polzer, T Herold, NP Konstandin, B Ksienzyk, E Zellmeier, ... Blood, The Journal of the American Society of Hematology 122 (10), 1761-1769, 2013 | 67 | 2013 |
PAX5 biallelic genomic alterations define a novel subgroup of B-cell precursor acute lymphoblastic leukemia L Bastian, MP Schroeder, C Eckert, C Schlee, JO Tanchez, S Kämpf, ... Leukemia 33 (8), 1895-1909, 2019 | 59 | 2019 |
ZBTB7A mutations in acute myeloid leukaemia with t (8; 21) translocation L Hartmann, S Dutta, S Opatz, S Vosberg, K Reiter, G Leubolt, ... Nature communications 7 (1), 11733, 2016 | 58 | 2016 |
Clonal heterogeneity of FLT3-ITD detected by high-throughput amplicon sequencing correlates with adverse prognosis in acute myeloid leukemia K Schranz, M Hubmann, E Harin, S Vosberg, T Herold, KH Metzeler, ... Oncotarget 9 (53), 30128, 2018 | 42 | 2018 |
DNA methylation epitypes highlight underlying developmental and disease pathways in acute myeloid leukemia B Giacopelli, M Wang, A Cleary, YZ Wu, AR Schultz, M Schmutz, ... Genome research 31 (5), 747-761, 2021 | 26 | 2021 |
FAT1 expression and mutations in adult acute lymphoblastic leukemia M Neumann, M Seehawer, C Schlee, S Vosberg, S Heesch, ... Blood cancer journal 4 (6), e224-e224, 2014 | 25 | 2014 |
Fusion gene detection by RNA-sequencing complements diagnostics of acute myeloid leukemia and identifies recurring NRIP1-MIR99AHG rearrangements P Kerbs, S Vosberg, S Krebs, A Graf, H Blum, A Swoboda, AMN Batcha, ... Haematologica 107 (1), 100, 2022 | 24 | 2022 |
Disease modeling on tumor organoids implicates AURKA as a therapeutic target in liver metastatic colorectal cancer SL Boos, LP Loevenich, S Vosberg, T Engleitner, R Öllinger, J Kumbrink, ... Cellular and Molecular Gastroenterology and Hepatology 13 (2), 517-540, 2022 | 21 | 2022 |
Relapse of acute myeloid leukemia after allogeneic stem cell transplantation is associated with gain of WT1 alterations and high mutation load S Vosberg, L Hartmann, KH Metzeler, NP Konstandin, S Schneider, ... Haematologica 103 (12), e581, 2018 | 18 | 2018 |
Acute myeloid leukemia with del(9q) is characterized by frequent mutations of NPM1, DNMT3A, WT1 and low expression of TLE4 T Herold, KH Metzeler, S Vosberg, L Hartmann, V Jurinovic, S Opatz, ... Genes, Chromosomes and Cancer 56 (1), 75-86, 2017 | 18 | 2017 |