A simplified, Langendorff-free method for concomitant isolation of viable cardiac myocytes and nonmyocytes from the adult mouse heart M Ackers-Johnson, PY Li, AP Holmes, SM O’Brien, D Pavlovic, RS Foo Circulation research 119 (8), 909-920, 2016 | 432 | 2016 |
PITX2 Modulates Atrial Membrane Potential and the Antiarrhythmic Effects of Sodium-Channel Blockers F Syeda, AP Holmes, TY Yu, S Tull, SM Kuhlmann, D Pavlovic, D Betney, ... Journal of the American College of Cardiology 68 (17), 1881-1894, 2016 | 98 | 2016 |
ElectroMap: high-throughput open-source software for analysis and mapping of cardiac electrophysiology C O’Shea, AP Holmes, TY Yu, J Winter, SP Wells, J Correia, BJ Boukens, ... Scientific reports 9 (1), 1389, 2019 | 74 | 2019 |
Reduced left atrial cardiomyocyte PITX2 and elevated circulating BMP10 predict atrial fibrillation after ablation JS Reyat, W Chua, VR Cardoso, A Witten, PM Kastner, SN Kabir, ... JCI insight 5 (16), 2020 | 56 | 2020 |
Cardiac optogenetics and optical mapping–overcoming spectral congestion in all-optical cardiac electrophysiology C O’shea, AP Holmes, J Winter, J Correia, X Ou, R Dong, S He, P Kirchhof, ... Frontiers in physiology 10, 182, 2019 | 53 | 2019 |
AMP-activated protein kinase deficiency blocks the hypoxic ventilatory response and thus precipitates hypoventilation and apnea AD Mahmoud, S Lewis, L Juričić, UA Udoh, S Hartmann, MA Jansen, ... American journal of respiratory and critical care medicine 193 (9), 1032-1043, 2016 | 48 | 2016 |
Cardiac optical mapping–State-of-the-art and future challenges C O’Shea, SN Kabir, AP Holmes, M Lei, L Fabritz, K Rajpoot, D Pavlovic The international journal of biochemistry & cell biology 126, 105804, 2020 | 43 | 2020 |
Adrenaline release evokes hyperpnoea and an increase in ventilatory CO2 sensitivity during hypoglycaemia: a role for the carotid body EL Thompson, CJ Ray, AP Holmes, RL Pye, CN Wyatt, AM Coney, ... The Journal of physiology 594 (15), 4439-4452, 2016 | 42 | 2016 |
A Regional Reduction in Ito and IKACh in the Murine Posterior Left Atrial Myocardium Is Associated with Action Potential Prolongation and Increased Ectopic Activity AP Holmes, TY Yu, S Tull, F Syeda, SM Kuhlmann, SM O’Brien, P Patel, ... PloS one 11 (5), e0154077, 2016 | 38 | 2016 |
An automated system using spatial oversampling for optical mapping in murine atria. Development and validation with monophasic and transmembrane action potentials TY Yu, F Syeda, AP Holmes, B Osborne, H Dehghani, KL Brain, ... Progress in biophysics and molecular biology 115 (2-3), 340-348, 2014 | 29 | 2014 |
Glycogen metabolism protects against metabolic insult to preserve carotid body function during glucose deprivation AP Holmes, PJ Turner, P Carter, W Leadbeater, CJ Ray, D Hauton, ... The Journal of Physiology 592 (20), 4493-4506, 2014 | 23 | 2014 |
Is Carotid Body Physiological O2 Sensitivity Determined by a Unique Mitochondrial Phenotype? AP Holmes, CJ Ray, AM Coney, P Kumar Frontiers in physiology 9, 562, 2018 | 22 | 2018 |
Exploring the neurogenic differentiation of human dental pulp stem cells AA Al-Maswary, M O’Reilly, AP Holmes, AD Walmsley, PR Cooper, ... PLoS One 17 (11), e0277134, 2022 | 21 | 2022 |
Moderate inhibition of mitochondrial function augments carotid body hypoxic sensitivity AP Holmes, PJ Turner, KJ Buckler, P Kumar Pflügers Archiv-European Journal of Physiology 468, 143-155, 2016 | 21 | 2016 |
Bicarbonate-sensitive soluble and transmembrane adenylyl cyclases in peripheral chemoreceptors AR Nunes, APS Holmes, V Sample, P Kumar, MJ Cann, EC Monteiro, ... Respiratory physiology & neurobiology 188 (2), 83-93, 2013 | 21 | 2013 |
Ecto-5′-nucleotidase, adenosine and transmembrane adenylyl cyclase signalling regulate basal carotid body chemoafferent outflow and establish the sensitivity to hypercapnia AP Holmes, AR Nunes, MJ Cann, P Kumar Arterial chemoreceptors in physiology and pathophysiology, 279-289, 2015 | 19 | 2015 |
Revisiting cAMP signaling in the carotid body AR Nunes, AP Holmes, SV Conde, EB Gauda, EC Monteiro Frontiers in physiology 5, 406, 2014 | 19 | 2014 |
Ecto‐5′‐nucleotidase (CD73) regulates peripheral chemoreceptor activity and cardiorespiratory responses to hypoxia AP Holmes, CJ Ray, SA Pearson, AM Coney, P Kumar The Journal of Physiology 596 (15), 3137-3148, 2018 | 18 | 2018 |
Mitochondrial succinate metabolism and reactive oxygen species are important but not essential for eliciting carotid body and ventilatory responses to hypoxia in the rat A Swiderska, AM Coney, AA Alzahrani, HS Aldossary, N Batis, CJ Ray, ... Antioxidants 10 (6), 840, 2021 | 16 | 2021 |
High resolution optical mapping of cardiac electrophysiology in pre-clinical models C O’Shea, J Winter, SN Kabir, M O’Reilly, SP Wells, O Baines, ... Scientific Data 9 (1), 135, 2022 | 15 | 2022 |