| Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large B Beutler, Z Jiang, P Georgel, K Crozat, B Croker, S Rutschmann, X Du, ... Annu. Rev. Immunol. 24 (1), 353-389, 2006 | 1007 | 2006 |
| ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization W Sun, Y Li, L Chen, H Chen, F You, X Zhou, Y Zhou, Z Zhai, D Chen, ... Proceedings of the National Academy of Sciences 106 (21), 8653-8658, 2009 | 869 | 2009 |
| CD14 is required for MyD88-independent LPS signaling Z Jiang, P Georgel, X Du, L Shamel, S Sovath, S Mudd, M Huber, C Kalis, ... Nature immunology 6 (6), 565-570, 2005 | 838 | 2005 |
| Toll-like receptor 3-mediated activation of NF-κB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN-β Z Jiang, TW Mak, G Sen, X Li Proceedings of the National Academy of Sciences 101 (10), 3533-3538, 2004 | 513 | 2004 |
| Manganese increases the sensitivity of the cGAS-STING pathway for double-stranded DNA and is required for the host defense against DNA viruses C Wang, Y Guan, M Lv, R Zhang, Z Guo, X Wei, X Du, J Yang, T Li, Y Wan, ... Immunity 48 (4), 675-687. e7, 2018 | 452 | 2018 |
| Manganese is critical for antitumor immune responses via cGAS-STING and improves the efficacy of clinical immunotherapy M Lv, M Chen, R Zhang, W Zhang, C Wang, Y Zhang, X Wei, Y Guan, ... Cell research 30 (11), 966-979, 2020 | 445 | 2020 |
| Hypersusceptibility to vesicular stomatitis virus infection in Dicer1-deficient mice is due to impaired miR24 and miR93 expression M Otsuka, Q Jing, P Georgel, L New, J Chen, J Mols, YJ Kang, Z Jiang, ... Immunity 27 (1), 123-134, 2007 | 445 | 2007 |
| Activation of STAT6 by STING is critical for antiviral innate immunity H Chen, H Sun, F You, W Sun, X Zhou, L Chen, J Yang, Y Wang, H Tang, ... Cell 147 (2), 436-446, 2011 | 425 | 2011 |
| Poly (dI· dC)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFκB and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway … Z Jiang, M Zamanian-Daryoush, H Nie, AM Silva, BRG Williams, X Li Journal of Biological Chemistry 278 (19), 16713-16719, 2003 | 384 | 2003 |
| Interleukin-1 (IL-1) receptor-associated kinase-dependent IL-1-induced signaling complexes phosphorylate TAK1 and TAB2 at the plasma membrane and activate TAK1 in the cytosol Z Jiang, J Ninomiya-Tsuji, Y Qian, K Matsumoto, X Li Molecular and cellular biology, 2002 | 379 | 2002 |
| PCBP2 mediates degradation of the adaptor MAVS via the HECT ubiquitin ligase AIP4 F You, H Sun, X Zhou, W Sun, S Liang, Z Zhai, Z Jiang Nature immunology 10 (12), 1300-1308, 2009 | 341 | 2009 |
| STING directly activates autophagy to tune the innate immune response D Liu, H Wu, C Wang, Y Li, H Tian, S Siraj, SA Sehgal, X Wang, J Wang, ... Cell Death & Differentiation 26 (9), 1735-1749, 2019 | 294 | 2019 |
| Vesicular stomatitis virus glycoprotein G activates a specific antiviral Toll-like receptor 4-dependent pathway P Georgel, Z Jiang, S Kunz, E Janssen, J Mols, K Hoebe, S Bahram, ... Virology 362 (2), 304-313, 2007 | 272 | 2007 |
| A toll-like receptor 2-responsive lipid effector pathway protects mammals against skin infections with gram-positive bacteria P Georgel, K Crozat, X Lauth, E Makrantonaki, H Seltmann, S Sovath, ... Infection and immunity 73 (8), 4512-4521, 2005 | 240 | 2005 |
| Apoptotic caspases suppress type I interferon production via the cleavage of cGAS, MAVS, and IRF3 X Ning, Y Wang, M Jing, M Sha, M Lv, P Gao, R Zhang, X Huang, ... Molecular cell 74 (1), 19-31. e7, 2019 | 230 | 2019 |
| R‐form LPS, the master key to the activation ofTLR4/MD‐2‐positive cells M Huber, C Kalis, S Keck, Z Jiang, P Georgel, X Du, L Shamel, S Sovath, ... European journal of immunology 36 (3), 701-711, 2006 | 230 | 2006 |
| The structural basis for the sensing and binding of cyclic di-GMP by STING YH Huang, XY Liu, XX Du, ZF Jiang, XD Su Nature structural & molecular biology 19 (7), 728-730, 2012 | 227 | 2012 |
| Inflammasome activation triggers caspase-1-mediated cleavage of cGAS to regulate responses to DNA virus infection Y Wang, X Ning, P Gao, S Wu, M Sha, M Lv, X Zhou, J Gao, R Fang, ... Immunity 46 (3), 393-404, 2017 | 222 | 2017 |
| Pellino 1 is required for interleukin-1 (IL-1)-mediated signaling through its interaction with the IL-1 receptor-associated kinase 4 (IRAK4)-IRAK-tumor necrosis factor receptor … Z Jiang, HJ Johnson, H Nie, J Qin, TA Bird, X Li Journal of Biological Chemistry 278 (13), 10952-10956, 2003 | 217 | 2003 |
| IL-1-induced NFκB and c-Jun N-terminal kinase (JNK) activation diverge at IL-1 receptor-associated kinase (IRAK) X Li, M Commane, Z Jiang, GR Stark Proceedings of the National Academy of Sciences 98 (8), 4461-4465, 2001 | 215 | 2001 |
