Pulmonary macrophages: key players in the innate defence of the airways AJ Byrne, SA Mathie, LG Gregory, CM Lloyd Thorax 70 (12), 1189-1196, 2015 | 477 | 2015 |
Pulmonary macrophages: a new therapeutic pathway in fibrosing lung disease? AJ Byrne, TM Maher, CM Lloyd Trends in molecular medicine 22 (4), 303-316, 2016 | 297 | 2016 |
IFN-λ resolves inflammation via suppression of neutrophil infiltration and IL-1β production K Blazek, HL Eames, M Weiss, AJ Byrne, D Perocheau, JE Pease, ... Journal of Experimental Medicine 212 (6), 845-853, 2015 | 242 | 2015 |
Interleukin-11 is a therapeutic target in idiopathic pulmonary fibrosis B Ng, J Dong, G D’Agostino, S Viswanathan, AA Widjaja, WW Lim, ... Science translational medicine 11 (511), eaaw1237, 2019 | 226 | 2019 |
Pulmonary epithelial cell-derived cytokine TGF-β1 is a critical cofactor for enhanced innate lymphoid cell function L Denney, AJ Byrne, TJ Shea, JS Buckley, JE Pease, GMF Herledan, ... Immunity 43 (5), 945-958, 2015 | 162 | 2015 |
IRF5 controls both acute and chronic inflammation M Weiss, AJ Byrne, K Blazek, DG Saliba, JE Pease, D Perocheau, ... Proceedings of the National Academy of Sciences 112 (35), 11001-11006, 2015 | 142 | 2015 |
IRF5 Is a Specific Marker of Inflammatory Macrophages In Vivo M Weiss, K Blazek, AJ Byrne, DP Perocheau, IA Udalova Mediators of inflammation 2013 (1), 245804, 2013 | 135 | 2013 |
Dynamics of human monocytes and airway macrophages during healthy aging and after transplant AJ Byrne, JE Powell, BJ O’Sullivan, PP Ogger, A Hoffland, J Cook, ... Journal of Experimental Medicine 217 (3), e20191236, 2020 | 123 | 2020 |
IRF5: RelA interaction targets inflammatory genes in macrophages DG Saliba, A Heger, HL Eames, S Oikonomopoulos, A Teixeira, K Blazek, ... Cell reports 8 (5), 1308-1317, 2014 | 111 | 2014 |
Itaconate controls the severity of pulmonary fibrosis PP Ogger, GJ Albers, RJ Hewitt, BJ O’Sullivan, JE Powell, E Calamita, ... Science immunology 5 (52), eabc1884, 2020 | 95 | 2020 |
Antigen-fixed leukocytes tolerize Th2 responses in mouse models of allergy CB Smarr, CL Hsu, AJ Byrne, SD Miller, PJ Bryce The Journal of Immunology 187 (10), 5090-5098, 2011 | 93 | 2011 |
The transferrin receptor CD71 delineates functionally distinct airway macrophage subsets during idiopathic pulmonary fibrosis SJ Allden, PP Ogger, P Ghai, P McErlean, R Hewitt, R Toshner, ... American journal of respiratory and critical care medicine 200 (2), 209-219, 2019 | 92 | 2019 |
Macrophage metabolic reprogramming during chronic lung disease PP Ogger, AJ Byrne Mucosal immunology 14 (2), 282-295, 2021 | 67 | 2021 |
The respiratory microbiome in chronic hypersensitivity pneumonitis is distinct from that of idiopathic pulmonary fibrosis R Invernizzi, BG Wu, J Barnett, P Ghai, S Kingston, RJ Hewitt, J Feary, ... American journal of respiratory and critical care medicine 203 (3), 339-347, 2021 | 56 | 2021 |
Inception of early-life allergen–induced airway hyperresponsiveness is reliant on IL-13+CD4+ T cells S Saglani, LG Gregory, AK Manghera, WJ Branchett, F Uwadiae, ... Science immunology 3 (27), eaan4128, 2018 | 55 | 2018 |
Bacterial burden in the lower airways predicts disease progression in idiopathic pulmonary fibrosis and is independent of radiological disease extent R Invernizzi, J Barnett, B Rawal, A Nair, P Ghai, S Kingston, F Chua, Z Wu, ... European Respiratory Journal 55 (4), 2020 | 50 | 2020 |
Anaphylactic responses to histamine in mice utilize both histamine receptors 1 and 2 JB Wechsler, HA Schroeder, AJ Byrne, KB Chien, PJ Bryce Allergy 68 (10), 1338-1340, 2013 | 37 | 2013 |
Lung macrophages contribute to house dust mite driven airway remodeling via HIF-1α AJ Byrne, CP Jones, K Gowers, SM Rankin, CM Lloyd PLoS One 8 (7), e69246, 2013 | 37 | 2013 |
A critical role for IRF5 in regulating allergic airway inflammation AJ Byrne, M Weiss, SA Mathie, SA Walker, HL Eames, D Saliba, CM Lloyd, ... Mucosal immunology 10 (3), 716-726, 2017 | 33 | 2017 |
CYFRA 21-1 predicts progression in idiopathic pulmonary fibrosis: a prospective longitudinal analysis of the PROFILE cohort PL Molyneaux, WA Fahy, AJ Byrne, R Braybrooke, P Saunders, ... American journal of respiratory and critical care medicine 205 (12), 1440-1448, 2022 | 24 | 2022 |