A focused fragment library targeting the antibiotic resistance enzyme-Oxacillinase-48: Synthesis, structural evaluation and inhibitor design S Akhter, BA Lund, A Ismael, M Langer, J Isaksson, T Christopeit, ... European journal of medicinal chemistry 145, 634-648, 2018 | 35 | 2018 |
Dissemination and characteristics of a novel plasmid-encoded carbapenem-hydrolyzing class D β-lactamase, OXA-436, found in isolates from four patients at six different … Ø Samuelsen, F Hansen, B Aasnæs, H Hasman, BA Lund, HKS Leiros, ... Antimicrobial Agents and Chemotherapy 62 (1), 10.1128/aac. 01260-17, 2018 | 32 | 2018 |
Screening and design of inhibitor scaffolds for the antibiotic resistance oxacillinase-48 (OXA-48) through surface plasmon resonance screening BA Lund, T Christopeit, Y Guttormsen, A Bayer, HKS Leiros Journal of Medicinal Chemistry 59 (11), 5542-5554, 2016 | 31 | 2016 |
Addressing the glycine‐rich loop of protein kinases by a multi‐facetted interaction network: inhibition of PKA and a PKB mimic BS Lauber, LA Hardegger, AK Asraful, BA Lund, O Dumele, M Harder, ... Chemistry–A European Journal 22 (1), 211-221, 2016 | 29 | 2016 |
A high-throughput, restriction-free cloning and screening strategy based on ccd B-gene replacement BA Lund, HKS Leiros, GEK Bjerga Microbial Cell Factories 13, 1-7, 2014 | 28 | 2014 |
Cryptic β-lactamase evolution is driven by low β-lactam concentrations C Fröhlich, JA Gama, K Harms, VHA Hirvonen, BA Lund, ... Msphere 6 (2), 10.1128/msphere. 00108-21, 2021 | 17 | 2021 |
The biological assembly of OXA‐48 reveals a dimer interface with high charge complementarity and very high affinity BA Lund, AM Thomassen, BHB Nesheim, TJO Carlsen, J Isaksson, ... The FEBS Journal 285 (22), 4214-4228, 2018 | 14 | 2018 |
Structure, activity and thermostability investigations of OXA-163, OXA-181 and OXA-245 using biochemical analysis, crystal structures and differential scanning calorimetry analysis BA Lund, AM Thomassen, TJO Carlsen, HKS Leiros Acta Crystallographica Section F: Structural Biology Communications 73 (10 …, 2017 | 13 | 2017 |
Structural origins of AGC protein kinase inhibitor selectivities: PKA as a drug discovery tool E Åberg, B Lund, A Pflug, OA Gani, U Rothweiler, TM de Oliveira, ... Biological chemistry 393 (10), 1121-1129, 2012 | 13 | 2012 |
Structure and mechanism of a cold-adapted bacterial lipase F van der Ent, BA Lund, L Svalberg, M Purg, G Chukwu, M Widersten, ... Biochemistry 61 (10), 933-942, 2022 | 10 | 2022 |
Computational design of the temperature optimum of an enzyme reaction F van der Ent, S Skagseth, BA Lund, J Sočan, JJ Griese, BO Brandsdal, ... Science Advances 9 (26), eadi0963, 2023 | 7 | 2023 |
Side‐Chain Interactions in d/l Peptide Nanotubes: Studies by Crystallography, NMR Spectroscopy and Molecular Dynamics MR Silk, JR Price, B Mohanty, HKS Leiros, BA Lund, PE Thompson, ... Chemistry–A European Journal 27 (58), 14489-14500, 2021 | 7 | 2021 |
Regiodivergent Synthesis of 11H‐Indolo[3,2‐c]quinolines and Neocryptolepine from a Common Starting Material KS Håheim, BA Lund, MO Sydnes European Journal of Organic Chemistry 26 (13), e202300137, 2023 | 5 | 2023 |
Accurate computation of thermodynamic activation parameters in the chorismate mutase reaction from empirical valence bond simulations RS Wilkins, BA Lund, GV Isaksen, J Åqvist, BO Brandsdal Journal of Chemical Theory and Computation 20 (1), 451-458, 2023 | 4 | 2023 |
Conformational tuning improves the stability of spirocyclic nitroxides with long paramagnetic relaxation times MP Sowiński, S Gahlawat, BA Lund, AL Warnke, KH Hopmann, JE Lovett, ... Communications Chemistry 6 (1), 111, 2023 | 3 | 2023 |
ThermoSlope: A software for determining thermodynamic parameters from single steady-state experiments BA Lund, BO Brandsdal Molecules 26 (23), 7155, 2021 | 3 | 2021 |
Biochemical and biophysical characterization of the OXA-48-like carbapenemase OXA-436 BA Lund, AM Thomassen, TJW Carlsen, HKS Leiros Structural Biology and Crystallization Communications 77 (9), 312-318, 2021 | 2 | 2021 |
Full wwPDB X-ray Structure Validation Report i H Wang, E Gouaux Word wide protein data bank, 2009 | 2 | 2009 |
The ambivalence of connexin43 Gap peptides in cardioprotection of the isolated heart against ischemic injury AT Falck, BA Lund, D Johansen, T Lund, K Ytrehus International Journal of Molecular Sciences 23 (17), 10197, 2022 | 1 | 2022 |
Biotech applications of protein kinase affinity interactions BA Lund Tromso, 2013 | 1 | 2013 |