An evolutionarily conserved function of polycomb silences the MHC class I antigen presentation pathway and enables immune evasion in cancer ML Burr, CE Sparbier, KL Chan, YC Chan, A Kersbergen, EYN Lam, ... Cancer cell 36 (4), 385-401. e8, 2019 | 459 | 2019 |
Transmission of a fatal clonal tumor by biting occurs due to depleted MHC diversity in a threatened carnivorous marsupial HV Siddle, A Kreiss, MDB Eldridge, E Noonan, CJ Clarke, S Pyecroft, ... Proceedings of the National Academy of Sciences 104 (41), 16221-16226, 2007 | 337 | 2007 |
Reversible epigenetic down-regulation of MHC molecules by devil facial tumour disease illustrates immune escape by a contagious cancer HV Siddle, A Kreiss, C Tovar, CK Yuen, Y Cheng, K Belov, K Swift, ... Proceedings of the National Academy of Sciences 110 (13), 5103-5108, 2013 | 233 | 2013 |
A second transmissible cancer in Tasmanian devils RJ Pye, D Pemberton, C Tovar, JMC Tubio, KA Dun, S Fox, J Darby, ... Proceedings of the National Academy of Sciences 113 (2), 374-379, 2016 | 231 | 2016 |
Genome sequence of an Australian kangaroo, Macropus eugenii, provides insight into the evolution of mammalian reproduction and development MB Renfree, AT Papenfuss, JE Deakin, J Lindsay, T Heider, K Belov, ... Genome biology 12 (8), R81, 2011 | 204 | 2011 |
MHC gene copy number variation in Tasmanian devils: implications for the spread of a contagious cancer HV Siddle, J Marzec, Y Cheng, M Jones, K Belov Proceedings of the Royal Society B: Biological Sciences 277 (1690), 2001-2006, 2010 | 173 | 2010 |
Reconstructing an ancestral mammalian immune supercomplex from a marsupial major histocompatibility complex K Belov, JE Deakin, AT Papenfuss, ML Baker, SD Melman, HV Siddle, ... PLoS biology 4 (3), 2006 | 164 | 2006 |
Demonstration of immune responses against devil facial tumour disease in wild Tasmanian devils R Pye, R Hamede, HV Siddle, A Caldwell, GW Knowles, K Swift, A Kreiss, ... Biology letters 12 (10), 20160553, 2016 | 112 | 2016 |
The origins and vulnerabilities of two transmissible cancers in Tasmanian devils MR Stammnitz, THH Coorens, KC Gori, D Hayes, B Fu, J Wang, ... Cancer Cell 33 (4), 607-619. e15, 2018 | 107 | 2018 |
The Immune Response of the Tasmanian Devil (Sarcophilus harrisii) and Devil Facial Tumour Disease GM Woods, A Kreiss, K Belov, HV Siddle, DL Obendorf, HK Muller EcoHealth 4 (3), 338-345, 2007 | 90 | 2007 |
Regression of devil facial tumour disease following immunotherapy in immunised Tasmanian devils C Tovar, RJ Pye, A Kreiss, Y Cheng, GK Brown, J Darby, RC Malley, ... Scientific reports 7 (1), 1-14, 2017 | 78 | 2017 |
Characterization of major histocompatibility complex class I and class II genes from the Tasmanian devil (Sarcophilus harrisii) HV Siddle, C Sanderson, K Belov Immunogenetics 59 (9), 753-760, 2007 | 75 | 2007 |
Immunology of naturally transmissible tumours HV Siddle, J Kaufman Immunology 144 (1), 11-20, 2015 | 71 | 2015 |
Antigen-presenting genes and genomic copy number variations in the Tasmanian devil MHC Y Cheng, A Stuart, K Morris, R Taylor, H Siddle, J Deakin, M Jones, ... BMC genomics 13 (1), 87, 2012 | 69 | 2012 |
A tale of two tumours: comparison of the immune escape strategies of contagious cancers HV Siddle, J Kaufman Molecular immunology 55 (2), 190-193, 2013 | 55 | 2013 |
MHC-linked and un-linked class I genes in the wallaby HV Siddle, JE Deakin, P Coggill, E Hart, Y Cheng, ESW Wong, J Harrow, ... BMC genomics 10 (1), 310, 2009 | 52 | 2009 |
The ERBB-STAT3 axis drives Tasmanian devil facial tumor disease L Kosack, B Wingelhofer, A Popa, A Orlova, B Agerer, B Vilagos, P Majek, ... Cancer cell 35 (1), 125-139. e9, 2019 | 48 | 2019 |
The newly-arisen Devil facial tumour disease 2 (DFT2) reveals a mechanism for the emergence of a contagious cancer A Caldwell, R Coleby, C Tovar, MR Stammnitz, YM Kwon, RS Owen, ... Elife 7, e35314, 2018 | 47 | 2018 |
The ecology and evolution of wildlife cancers: Applications for management and conservation R Hamede, R Owen, H Siddle, S Peck, M Jones, AM Dujon, M Giraudeau, ... Evolutionary Applications, 2019 | 42 | 2019 |
Tracing the rise of malignant cell lines: distribution, epidemiology and evolutionary interactions of two transmissible cancers in Tasmanian devils S James, G Jennings, YM Kwon, M Stammnitz, A Fraik, A Storfer, S Comte, ... Evolutionary applications 12 (9), 1772-1780, 2019 | 41 | 2019 |