Immunosuppressive plasma cells impede T-cell-dependent immunogenic chemotherapy S Shalapour, J Font-Burgada, G Di Caro, Z Zhong, E Sanchez-Lopez, ... Nature 521 (7550), 94-98, 2015 | 535 | 2015 |
ER stress cooperates with hypernutrition to trigger TNF-dependent spontaneous HCC development H Nakagawa, A Umemura, K Taniguchi, J Font-Burgada, D Dhar, H Ogata, ... Cancer cell 26 (3), 331-343, 2014 | 500 | 2014 |
Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity S Shalapour, XJ Lin, IN Bastian, J Brain, AD Burt, AA Aksenov, ... Nature 551 (7680), 340-345, 2017 | 493 | 2017 |
Identification of liver cancer progenitors whose malignant progression depends on autocrine IL-6 signaling G He, D Dhar, H Nakagawa, J Font-Burgada, H Ogata, Y Jiang, ... Cell 155 (2), 384-396, 2013 | 485 | 2013 |
DNA methylation markers for diagnosis and prognosis of common cancers X Hao, H Luo, M Krawczyk, W Wei, W Wang, J Wang, K Flagg, J Hou, ... Proceedings of the National Academy of Sciences 114 (28), 7414-7419, 2017 | 436 | 2017 |
Mechanisms of liver fibrosis and its role in liver cancer D Dhar, J Baglieri, T Kisseleva, DA Brenner Experimental Biology and Medicine 245 (2), 96-108, 2020 | 281 | 2020 |
ER stress drives lipogenesis and steatohepatitis via caspase-2 activation of S1P JY Kim, R Garcia-Carbonell, S Yamachika, P Zhao, D Dhar, R Loomba, ... Cell 175 (1), 133-145. e15, 2018 | 281 | 2018 |
Syrian hamster as a permissive immunocompetent animal model for the study of oncolytic adenovirus vectors MA Thomas, JF Spencer, MC La Regina, D Dhar, AE Tollefson, K Toth, ... Cancer research 66 (3), 1270-1276, 2006 | 191 | 2006 |
Liver cancer initiation requires p53 inhibition by CD44-enhanced growth factor signaling D Dhar, L Antonucci, H Nakagawa, JY Kim, E Glitzner, S Caruso, ... Cancer cell 33 (6), 1061-1077. e6, 2018 | 186 | 2018 |
Hexadecyloxypropyl-cidofovir, CMX001, prevents adenovirus-induced mortality in a permissive, immunosuppressed animal model K Toth, JF Spencer, D Dhar, JE Sagartz, RML Buller, GR Painter, ... Proceedings of the National Academy of Sciences 105 (20), 7293-7297, 2008 | 147 | 2008 |
Loss of liver E-cadherin induces sclerosing cholangitis and promotes carcinogenesis H Nakagawa, Y Hikiba, Y Hirata, J Font-Burgada, K Sakamoto, ... Proceedings of the National Academy of Sciences 111 (3), 1090-1095, 2014 | 133 | 2014 |
Stress-activated NRF2-MDM2 cascade controls neoplastic progression in pancreas J Todoric, L Antonucci, G Di Caro, N Li, X Wu, NK Lytle, D Dhar, ... Cancer cell 32 (6), 824-839. e8, 2017 | 121 | 2017 |
IKKα activation of NOTCH links tumorigenesis via FOXA2 suppression M Liu, DF Lee, CT Chen, CJ Yen, LY Li, HJ Lee, CJ Chang, WC Chang, ... Molecular cell 45 (2), 171-184, 2012 | 112 | 2012 |
Activated hepatic stellate cells and portal fibroblasts contribute to cholestatic liver fibrosis in MDR2 knockout mice T Nishio, R Hu, Y Koyama, S Liang, SB Rosenthal, G Yamamoto, D Karin, ... Journal of Hepatology 71 (3), 573-585, 2019 | 109 | 2019 |
Heterogeneity of HSC s in a Mouse Model of NASH SB Rosenthal, X Liu, S Ganguly, D Dhar, MP Pasillas, E Ricciardelli, RZ Li, ... Hepatology 74 (2), 667-685, 2021 | 86 | 2021 |
NADPH oxidase 1 in liver macrophages promotes inflammation and tumor development in mice S Liang, HY Ma, Z Zhong, D Dhar, X Liu, J Xu, Y Koyama, T Nishio, ... Gastroenterology 156 (4), 1156-1172. e6, 2019 | 85 | 2019 |
Oncolytic (replication-competent) adenoviruses as anticancer agents K Toth, D Dhar, WSM Wold Expert opinion on biological therapy 10 (3), 353-368, 2010 | 79 | 2010 |
Effect of preexisting immunity on oncolytic adenovirus vector INGN 007 antitumor efficacy in immunocompetent and immunosuppressed Syrian hamsters D Dhar, JF Spencer, K Toth, WSM Wold Journal of virology 83 (5), 2130-2139, 2009 | 76 | 2009 |
Liver carcinogenesis: from naughty chemicals to soothing fat and the surprising role of NRF2 M Karin, D Dhar Carcinogenesis 37 (6), 541-546, 2016 | 71 | 2016 |
INGN 007, an oncolytic adenovirus vector, replicates in Syrian hamsters but not mice: comparison of biodistribution studies B Ying, K Toth, JF Spencer, J Meyer, AE Tollefson, D Patra, D Dhar, ... Cancer gene therapy 16 (8), 625-637, 2009 | 60 | 2009 |