TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity K Williams, J Christensen, MT Pedersen, JV Johansen, PAC Cloos, ... Nature 473 (7347), 343-348, 2011 | 1103 | 2011 |
JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells D Pasini, PAC Cloos, J Walfridsson, L Olsson, JP Bukowski, JV Johansen, ... Nature 464 (7286), 306-310, 2010 | 628 | 2010 |
YAP/TAZ-dependent reprogramming of colonic epithelium links ECM remodeling to tissue regeneration S Yui, L Azzolin, M Maimets, MT Pedersen, RP Fordham, SL Hansen, ... Cell stem cell 22 (1), 35-49. e7, 2018 | 515 | 2018 |
EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas F Mohammad, S Weissmann, B Leblanc, DP Pandey, JW Højfeldt, ... Nature medicine 23 (4), 483-492, 2017 | 468 | 2017 |
Gene silencing triggers polycomb repressive complex 2 recruitment to CpG islands genome wide EM Riising, I Comet, B Leblanc, X Wu, JV Johansen, K Helin Molecular cell 55 (3), 347-360, 2014 | 449 | 2014 |
Fbxl10/Kdm2b recruits polycomb repressive complex 1 to CpG islands and regulates H2A ubiquitylation X Wu, JV Johansen, K Helin Molecular cell 49 (6), 1134-1146, 2013 | 420 | 2013 |
The histone demethylases JMJD1A and JMJD2B are transcriptional targets of hypoxia-inducible factor HIF S Beyer, MM Kristensen, KS Jensen, JV Johansen, P Staller Journal of Biological Chemistry 283 (52), 36542-36552, 2008 | 385 | 2008 |
Loss of TET2 in hematopoietic cells leads to DNA hypermethylation of active enhancers and induction of leukemogenesis KD Rasmussen, G Jia, JV Johansen, MT Pedersen, N Rapin, FO Bagger, ... Genes & development 29 (9), 910-922, 2015 | 270 | 2015 |
RSK is a principal effector of the RAS-ERK pathway for eliciting a coordinate promotile/invasive gene program and phenotype in epithelial cells U Doehn, C Hauge, SR Frank, CJ Jensen, K Duda, JV Nielsen, ... Molecular cell 35 (4), 511-522, 2009 | 246 | 2009 |
An interactive environment for agile analysis and visualization of ChIP-sequencing data M Lerdrup, JV Johansen, S Agrawal-Singh, K Hansen Nature structural & molecular biology 23 (4), 349-357, 2016 | 243 | 2016 |
Accurate recycling of parental histones reproduces the histone modification landscape during DNA replication N Reverón-Gómez, C González-Aguilera, KR Stewart-Morgan, N Petryk, ... Molecular cell 72 (2), 239-249. e5, 2018 | 208 | 2018 |
Jarid1b targets genes regulating development and is involved in neural differentiation SU Schmitz, M Albert, M Malatesta, L Morey, JV Johansen, M Bak, ... The EMBO journal 30 (22), 4586-4600, 2011 | 195 | 2011 |
The histone methyltransferase and putative oncoprotein MMSET is overexpressed in a large variety of human tumors HR Hudlebusch, E Santoni-Rugiu, R Simon, E Ralfkiær, HH Rossing, ... Clinical cancer research 17 (9), 2919-2933, 2011 | 175 | 2011 |
The chloride channel inhibitor NS3736 prevents bone resorption in ovariectomized rats without changing bone formation S Schaller, K Henriksen, C Sveigaard, AM Heegaard, N Hélix, M Stahlhut, ... Journal of Bone and Mineral Research 19 (7), 1144-1153, 2004 | 175 | 2004 |
The histone demethylase Jarid1b ensures faithful mouse development by protecting developmental genes from aberrant H3K4me3 M Albert, SU Schmitz, SM Kooistra, M Malatesta, C Morales Torres, ... PLoS genetics 9 (4), e1003461, 2013 | 128 | 2013 |
BRPF 3‐HBO 1 regulates replication origin activation and histone H3K14 acetylation Y Feng, A Vlassis, C Roques, ME Lalonde, C González‐Aguilera, ... The EMBO journal 35 (2), 176-192, 2016 | 116 | 2016 |
CRISPR/Cas9 engineering of adult mouse liver demonstrates that the Dnajb1–Prkaca gene fusion is sufficient to induce tumors resembling fibrolamellar hepatocellular carcinoma LH Engelholm, A Riaz, D Serra, F Dagnæs-Hansen, JV Johansen, ... Gastroenterology 153 (6), 1662-1673. e10, 2017 | 104 | 2017 |
Histone H4K20 methylation mediated chromatin compaction threshold ensures genome integrity by limiting DNA replication licensing M Shoaib, D Walter, PJ Gillespie, F Izard, B Fahrenkrog, D Lleres, ... Nature communications 9 (1), 3704, 2018 | 96 | 2018 |
Continual removal of H3K9 promoter methylation by Jmjd2 demethylases is vital for ESC self‐renewal and early development MT Pedersen, SM Kooistra, A Radzisheuskaya, A Laugesen, ... The EMBO journal 35 (14), 1550-1564, 2016 | 93 | 2016 |
The histone lysine demethylase JMJD3/KDM6B is recruited to p53 bound promoters and enhancer elements in a p53 dependent manner K Williams, J Christensen, J Rappsilber, AL Nielsen, JV Johansen, ... PLoS One 9 (5), e96545, 2014 | 93 | 2014 |