G-quadruplex formation within the promoter of the KRAS proto-oncogene and its effect on transcription S Cogoi, LE Xodo Nucleic acids research 34 (9), 2536-2549, 2006 | 827 | 2006 |
Effect pf 5-methylcytosine on the stability of triple-stranded DNA—a thermodynamic study LE Xodo, G Manzini, F Quadrifoglio, GA van der Marel, JH van Boom Nucleic acids research 19 (20), 5625-5631, 1991 | 274 | 1991 |
Evidence for intramolecularly folded i-DNA structures in biologically relevant CCC-repeat sequences G Manzini, N Yathindra, LE Xodo Nucleic acids research 22 (22), 4634-4640, 1994 | 232 | 1994 |
Structural polymorphism within a regulatory element of the human KRAS promoter: formation of G4-DNA recognized by nuclear proteins S Cogoi, M Paramasivam, B Spolaore, LE Xodo Nucleic acids research 36 (11), 3765-3780, 2008 | 193 | 2008 |
Triple helix formation by oligopurine-oligopyrimidine DNA fragments: electrophoretic and thermodynamic behavior G Manzini, LE Xodo, D Gasparotto, F Quadrifoglio, GA van der Marel, ... Journal of molecular biology 213 (4), 833-843, 1990 | 187 | 1990 |
Protein hnRNP A1 and its derivative Up1 unfold quadruplex DNA in the human KRAS promoter: implications for transcription M Paramasivam, A Membrino, S Cogoi, H Fukuda, H Nakagama, LE Xodo Nucleic acids research 37 (9), 2841-2853, 2009 | 160 | 2009 |
The KRAS promoter responds to Myc-associated zinc finger and poly (ADP-ribose) polymerase 1 proteins, which recognize a critical quadruplex-forming GA-element S Cogoi, M Paramasivam, A Membrino, KK Yokoyama, LE Xodo Journal of Biological Chemistry 285 (29), 22003-22016, 2010 | 159 | 2010 |
Spectroscopic and calorimetric investigation on the DNA triplex formed by d (CTCTTCTTTCTTTTCTTTCTTCTC) and d (GAGAAGAAAGA) at acidic pH LE Xodo, G Manzini, F Quadrifoglio Nucleic acids research 18 (12), 3557-3564, 1990 | 146 | 1990 |
HRAS is silenced by two neighboring G-quadruplexes and activated by MAZ, a zinc-finger transcription factor with DNA unfolding property S Cogoi, AE Shchekotikhin, LE Xodo Nucleic acids research 42 (13), 8379-8388, 2014 | 127 | 2014 |
G4-DNA Formation in the HRAS Promoter and Rational Design of Decoy Oligonucleotides for Cancer Therapy A Membrino, S Cogoi, EB Pedersen, LE Xodo PloS one 6 (9), e24421, 2011 | 126 | 2011 |
The regulatory G4 motif of the Kirsten ras (KRAS) gene is sensitive to guanine oxidation: implications on transcription S Cogoi, A Ferino, G Miglietta, EB Pedersen, LE Xodo Nucleic acids research 46 (2), 661-676, 2018 | 124 | 2018 |
MAZ-binding G4-decoy with locked nucleic acid and twisted intercalating nucleic acid modifications suppresses KRAS in pancreatic cancer cells and delays tumor … S Cogoi, S Zorzet, V Rapozzi, I Geci, EB Pedersen, LE Xodo Nucleic acids research 41 (7), 4049-4064, 2013 | 112 | 2013 |
Identification of a New G-Quadruplex Motif in the KRAS Promoter and Design of Pyrene-Modified G4-Decoys with Antiproliferative Activity in Pancreatic Cancer Cells S Cogoi, M Paramasivam, V Filichev, I Géci, EB Pedersen, LE Xodo Journal of medicinal chemistry 52 (2), 564-568, 2009 | 102 | 2009 |
Nitric oxide-mediated activity in anti-cancer photodynamic therapy V Rapozzi, E Della Pietra, S Zorzet, M Zacchigna, B Bonavida, LE Xodo Nitric oxide 30, 26-35, 2013 | 96 | 2013 |
Anticancer activity of cationic porphyrins in melanoma tumour-bearing mice and mechanistic in vitro studies V Rapozzi, S Zorzet, M Zacchigna, E Della Pietra, S Cogoi, LE Xodo Molecular cancer 13, 1-17, 2014 | 94 | 2014 |
Site‐directed inhibition of DNA replication by triple helix formation S Diviacco, V Rapozzi, L Xodo, C Hélène, F Quadrifoglio, ... The FASEB Journal 15 (14), 2660-2668, 2001 | 86 | 2001 |
Cellular uptake and binding of guanidine-modified phthalocyanines to KRAS/HRAS G-quadruplexes A Membrino, M Paramasivam, S Cogoi, J Alzeer, NW Luedtke, LE Xodo Chemical Communications 46 (4), 625-627, 2010 | 85 | 2010 |
Oligodeoxynucleotide folding in solution: loop size and stability of B-hairpins LE Xodo, G Manzini, F Quadrifoglio, GA Van der Marel, JH Van Boom Biochemistry 27 (17), 6321-6326, 1988 | 84 | 1988 |
DNA hairpin loops in solution. Correlation between primary structure, thermostability and reactivity with single-strand-specific nuclease from mung bean LE Xodo, G Manzini, F Quadrifoglio, G van der Marel, J van Boom Nucleic acids research 19 (7), 1505-1511, 1991 | 82 | 1991 |
RNA G-Quadruplexes in Kirsten Ras (KRAS) Oncogene as Targets for Small Molecules Inhibiting Translation G Miglietta, S Cogoi, J Marinello, G Capranico, AS Tikhomirov, ... Journal of Medicinal Chemistry 60 (23), 9448-9461, 2017 | 74 | 2017 |