Fundamental design principles for transcription-factor-based metabolite biosensors AA Mannan, D Liu, F Zhang, DA Oyarzún ACS synthetic biology 6 (10), 1851-1859, 2017 | 185 | 2017 |
Modeling and simulation of the main metabolism in Escherichia coli and its several single-gene knockout mutants with experimental verification TAA Kadir, AA Mannan, AM Kierzek, J McFadden, K Shimizu Microbial cell factories 9, 1-21, 2010 | 109 | 2010 |
Dynamic metabolic control: towards precision engineering of metabolism D Liu, AA Mannan, Y Han, DA Oyarzún, F Zhang Journal of Industrial Microbiology and Biotechnology 45 (7), 535-543, 2018 | 101 | 2018 |
Interrogation of global mutagenesis data with a genome scale model of Neisseria meningitidis to assess gene fitness in vitro and in sera TA Mendum, J Newcombe, AA Mannan, AM Kierzek, J McFadden Genome biology 12, 1-15, 2011 | 45 | 2011 |
Integrating kinetic model of E. coli with genome scale metabolic fluxes overcomes its open system problem and reveals bistability in central metabolism AA Mannan, Y Toya, K Shimizu, J McFadden, AM Kierzek, A Rocco PloS one 10 (10), e0139507, 2015 | 37 | 2015 |
MUFINS: multi-formalism interaction network simulator H Wu, A Von Kamp, V Leoncikas, W Mori, N Sahin, A Gevorgyan, C Linley, ... NPJ systems biology and applications 2 (1), 1-10, 2016 | 25 | 2016 |
Trade-offs in biosensor optimization for dynamic pathway engineering BK Verma, AA Mannan, F Zhang, DA Oyarzún ACS synthetic biology 11 (1), 228-240, 2021 | 18 | 2021 |
Designing an irreversible metabolic switch for scalable induction of microbial chemical production AA Mannan, DG Bates Nature Communications 12 (3419), 2021 | 17 | 2021 |
Metabolite sequestration enables rapid recovery from fatty acid depletion in Escherichia coli CJ Hartline, AA Mannan, D Liu, F Zhang, DA Oyarzún MBio 11 (2), 10.1128/mbio. 03112-19, 2020 | 17 | 2020 |
gcFront: a tool for determining a Pareto front of growth-coupled cell factory designs L Legon, C Corre, DG Bates, AA Mannan Bioinformatics 38 (14), 3657-3659, 2022 | 7 | 2022 |
Multiobjective optimization of gene circuits for metabolic engineering I Otero-Muras, AA Mannan, JR Banga, DA Oyarzún IFAC-PapersOnLine 52 (26), 13-16, 2019 | 7 | 2019 |
Natural host feedback simplifies the design of metabolic switches APS Darlington, AA Mannan, DG Bates 2023 62nd IEEE Conference on Decision and Control (CDC), 2693-2698, 2023 | 1 | 2023 |
Integration of Kinetic and Whole-Cell Stoichiometric Model for Hybrid Simulations of Bacterial Central Metabolism AA Mannan PQDT-Global, 2012 | 1 | 2012 |
In Silico Elucidation of Key Drivers of Staphyloccocus aureus–Staphyloccocus epidermidis–Induced Skin Damage in Atopic Dermatitis Lesions J Lee, AA Mannan, T Miyano, AD Irvine, RJ Tanaka JID Innovations 4 (3), 100269, 2024 | | 2024 |
Design principles for engineering bacteria to maximise chemical production from batch cultures AA Mannan, APS Darlington, RJ Tanaka, DG Bates bioRxiv, 2024.05. 23.595552, 2024 | | 2024 |
1012 In silico prediction of the targeted killing of S. aureus in coinfections with S. epidermidis in atopic dermatitis lesions AA Mannan, J Lee, T Miyano, R Tanaka Journal of Investigative Dermatology 143 (5), S173, 2023 | | 2023 |
Signaling Tug-of-War Delivers the Whole Message AY Weiße, AA Mannan, DA Oyarzún Cell Systems 3 (5), 414-416, 2016 | | 2016 |